Retinal Abnormalities and COVID
"Retinal microvascular abnormalities and impaired blood flow appear to be emerging as signature ocular manifestations of COVID-19 infections, researchers have found..."
Ocular manifestations of COVID-19 in the pediatric age group
“Episcleritis, conjunctivitis, optic neuritis, cranial nerve palsies, retinal vein occlusion, retinal vasculitis, retinal changes, orbital myositis, orbital cellulitis were reported in the literature with this emerging viral illness.”
In the Eye of the Storm: How Covid-19 Impacts the Eye
“It’s possible retinal injury is a consequence of vascular dysfunction around the eye related to the infection of epithelial cells lining blood vessels…Infected retinal ganglion cells may activate inflammatory signal pathways that damage nearby cells.”
Histopathology and SARS-CoV-2 Cellular Localization in Eye Tissues of COVID-19 Autopsies
Histopathology-SARSCoV2 Cellular Localization in Eye Tissues of COVID19:cytoid bodies,vascular changes,retinal edema,min/no inflam ocular;neuronal cells retinal inner/outer layers,ganglion cells,corneal epithelia,scleral fibroblasts,oligoden optic nerve
Retinal tissue and microvasculature loss in COVID-19 infection
Retinal tissue & microvasculature loss in COVID19 infection: Retinal volume was signif⬇️in outer 3 mm of macula in severe COVID19 group (p = 0.02). Total retinal vessel density was signif⬇️in severe COVID-19 vs normal/ mild COVID19 (p = 0.004 & 0.0057).
Histopathology and SARS-CoV-2 Cellular Localization in Eye Tissues of COVID-19 Autopsies
Autopsies have previously evidenced SARS viral persistence in gastrointestinal tissues including ocular tissues. This study detected SARS RNA in ocular fluids/tissue in 61% of cases; cornea 42%, horoid/sclera 50%, lens 53%, retina 35%, optic nerve 59%.
Chris Turnbull on Twitter
Comprehensive analysis of study thread on Twitter: New Study: Covid found to infect the eyes and replicate with in them: virus found in eyes months after infection:
'our data give us reason to believe that so-called long-Covid symptoms may include degenerative retinal disease.'
Study leader says.
Retinal findings in patients with COVID-19
Retinal findings in patients with COVID-19
COVID-19-Related Retinal Micro-vasculopathy – A Review of Current Evidence
COVID-19-Related Retinal Micro-vasculopathy
HUG on Twitter
The list of damage caused by SARS-CoV-2 infection is growing and now includes retina. This is what a prospective study by the HUG and the @UNIGEnews
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New Concern: COVID-19 could affect your eyesight
“Usually, it’ll cause a decrease in vision,” he said. “It could then cause a secondary cause of glaucoma, can also cause things like cataracts, retinal swelling. All kinds of problems inside the eye.”
Vitritis and Outer Retinal Abnormalities in a Patient with COVID-19 - PubMed
"a unique case of intraocular inflammation, vitritis and outer retinal changes in a patient with coronavirus disease (COVID-19)."
COVID-2019 Associated with Acquired Monocular Blindness - PubMed
Acute viral retinitis in patients with COVID-19 "severe blindness could be associated with SARS-CoV-2 infection... physicians should consider the possibility of coronavirus infection in patients with an abnormal fundus or suddenly vision loss."
Does COVID-19 lead to vision loss?
"Ophthalmologists should have a high index of suspicion for retinal vascular occlusions in patients presenting with decreased vision or blurry vision with a history of COVID-19 infection as prompt intervention may prevent irreversible visual loss:"
Vision-Threatening Retinal Condition Linked to COVID-19
Vision-Threatening Retinal Condition Linked to COVID-19 — Rates of rare retinal vein occlusion jumped after infection,
There is more to Sars-CoV-2 than meets the eye
"Coronavirus not only infects the human retina, but can also replicate in it"