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Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts
Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts
Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts
Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts
·pmc.ncbi.nlm.nih.gov·
Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts
Elevated serum mtDNA in COVID-19 patients is linked to SARS-CoV-2 envelope protein targeting mitochondrial VDAC1, inducing apoptosis and mtDNA release
Elevated serum mtDNA in COVID-19 patients is linked to SARS-CoV-2 envelope protein targeting mitochondrial VDAC1, inducing apoptosis and mtDNA release
“These findings suggest that SARS-CoV-2 E-protein induces mitochondrial dysfunction, apoptosis, and mtDNA release via VDAC1 modulation. mtDNA that accumulates in the blood activates the cGAS-STING pathway, triggering inflammatory cytokine and chemokine expression that contribute to the cytokine storm and tissue damage”
These findings suggest that SARS-CoV-2 E-protein induces mitochondrial dysfunction, apoptosis, and mtDNA release via VDAC1 modulation. mtDNA that accumulates in the blood activates the cGAS-STING pathway, triggering inflammatory cytokine and chemokine expression that contribute to the cytokine storm and tissue damage
·link.springer.com·
Elevated serum mtDNA in COVID-19 patients is linked to SARS-CoV-2 envelope protein targeting mitochondrial VDAC1, inducing apoptosis and mtDNA release
SARS-CoV-2 can cause lasting damage to cells’ energy production
SARS-CoV-2 can cause lasting damage to cells’ energy production

“SARS-CoV-2, the virus that causes COVID-19, can cause lasting damage to energy production by mitochondria in many organs of the body. Stopping the virus from hijacking mitochondrial energy production may be a novel way to prevent serious complications from SARS-CoV-2 infection.”

·nih.gov·
SARS-CoV-2 can cause lasting damage to cells’ energy production
This video about Long COVID and ME/CFS is now trending #5 on YouTube 🇩🇪
This video about Long COVID and ME/CFS is now trending #5 on YouTube 🇩🇪

translation/analysis thread on German Long Covid video which equates it with MECFS and calls ME “the most serious form of long covid.”

“currently it looks like an autoimmune disease where something has gone wrong with the vasculature, and both the mitochondrial dynamics and glycolytic metabolism are disturbed.

There are at least 500k patients in Germany.”

·x.com·
This video about Long COVID and ME/CFS is now trending #5 on YouTube 🇩🇪