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Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts
Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts
Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts
Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts
#Mitochondria#acute Covid#mitochondrial damage#mitochondrial dysfunction#Post-Acute Conditions
·pmc.ncbi.nlm.nih.gov·
Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts
COVID is still around and a risk to vulnerable people. What are the symptoms in 2025? And how long does it last?
COVID is still around and a risk to vulnerable people. What are the symptoms in 2025? And how long does it last?
“However, loss of smell still seems to be associated with some newer variants. A recent French study found anosmia was more frequently reported in people with JN.1.”
#Covid Isn't Over#risks#anosmia#Post-Acute Conditions#acute Covid#organ damage#Immune system#Smell loss
·search.app·
COVID is still around and a risk to vulnerable people. What are the symptoms in 2025? And how long does it last?
Elevated serum mtDNA in COVID-19 patients is linked to SARS-CoV-2 envelope protein targeting mitochondrial VDAC1, inducing apoptosis and mtDNA release
Elevated serum mtDNA in COVID-19 patients is linked to SARS-CoV-2 envelope protein targeting mitochondrial VDAC1, inducing apoptosis and mtDNA release
“These findings suggest that SARS-CoV-2 E-protein induces mitochondrial dysfunction, apoptosis, and mtDNA release via VDAC1 modulation. mtDNA that accumulates in the blood activates the cGAS-STING pathway, triggering inflammatory cytokine and chemokine expression that contribute to the cytokine storm and tissue damage”
These findings suggest that SARS-CoV-2 E-protein induces mitochondrial dysfunction, apoptosis, and mtDNA release via VDAC1 modulation. mtDNA that accumulates in the blood activates the cGAS-STING pathway, triggering inflammatory cytokine and chemokine expression that contribute to the cytokine storm and tissue damage
#Cell Damage#apoptosis#mitochondrial damage#Mitochondria#mtDNA#Post-Acute Conditions#acute Covid
·link.springer.com·
Elevated serum mtDNA in COVID-19 patients is linked to SARS-CoV-2 envelope protein targeting mitochondrial VDAC1, inducing apoptosis and mtDNA release
If anyone thinks musicians dropped like this before covid they are lying to themselves
If anyone thinks musicians dropped like this before covid they are lying to themselves
“Bieber cancelling his tour due to long covid complications, Harry Styles recently cancelling shows due to covid and now Springsteen cancelling shows just 3 weeks into their world tour, 2023 will be the year touring musicians show us there is no return to normal with endemic covid”
#musicians with Covid#Covid effects on the arts#inevitable effects of Forever Covid#Long Covid#Post-Acute Conditions#acute Covid#superspreader#Nate Bear
·x.com·
If anyone thinks musicians dropped like this before covid they are lying to themselves
She’s had covid “20-25” times since covid started—and that’s with confirmed positive tests at urgent care or the hospital because she has terrible symptoms with covid each and every time she’s had it. The doctor said “maybe your body’s not making the antibodies to fight it.”😭
She’s had covid “20-25” times since covid started—and that’s with confirmed positive tests at urgent care or the hospital because she has terrible symptoms with covid each and every time she’s had it. The doctor said “maybe your body’s not making the antibodies to fight it.”😭
“She’s had covid ‘20-25’ times since covid started—and that’s with confirmed positive tests at urgent care or the hospital because she has terrible symptoms with covid each and every time she’s had it. The doctor said ‘maybe your body’s not making the antibodies to fight it.’”😭
#Immune system#anecdote#Long Covid#Post-Acute Conditions#Video#acute Covid
·x.com·
She’s had covid “20-25” times since covid started—and that’s with confirmed positive tests at urgent care or the hospital because she has terrible symptoms with covid each and every time she’s had it. The doctor said “maybe your body’s not making the antibodies to fight it.”😭
This is my 15th semester teaching RN and NP students about Covid 19 pathophysiology. Not a lot has changed except for how much damage we now know the virus causes. It still baffles me that people don’t know it’s airborne, don’t know the risks. 1
This is my 15th semester teaching RN and NP students about Covid 19 pathophysiology. Not a lot has changed except for how much damage we now know the virus causes. It still baffles me that people don’t know it’s airborne, don’t know the risks. 1

“#CovidIsNotOver This is my 15th semester teaching RN and NP students about Covid 19 pathophysiology. Not a lot has changed except for how much damage we now know the virus causes. It still baffles me that people don’t know it’s airborne, don’t know the risks. 1”

Educational Thread:

#acute Covid#airborne#Post-Acute Conditions#Long Covid#risks#education#analysis#Discussion
·x.com·
This is my 15th semester teaching RN and NP students about Covid 19 pathophysiology. Not a lot has changed except for how much damage we now know the virus causes. It still baffles me that people don’t know it’s airborne, don’t know the risks. 1
SARS-CoV-2 Infection Dysregulates Cilia and Basal Cell Homeostasis in the Respiratory Epithelium of Hamsters
SARS-CoV-2 Infection Dysregulates Cilia and Basal Cell Homeostasis in the Respiratory Epithelium of Hamsters

Hamster study:

“severe" loss of cilia following a COVID infection. Cilia are small, hair-like structures that are an important part of the mucosal system.

#cilia#respiratory epithelium#mucociliary clearance#nasal damage#nasal epithelium#ciliary loss#Post-Acute Conditions#acute Covid
·mdpi.com·
SARS-CoV-2 Infection Dysregulates Cilia and Basal Cell Homeostasis in the Respiratory Epithelium of Hamsters
SARS-CoV-2 can cause lasting damage to cells’ energy production
SARS-CoV-2 can cause lasting damage to cells’ energy production

“SARS-CoV-2, the virus that causes COVID-19, can cause lasting damage to energy production by mitochondria in many organs of the body. Stopping the virus from hijacking mitochondrial energy production may be a novel way to prevent serious complications from SARS-CoV-2 infection.”

#Mitochondria#mitochondrial damage#Cell Damage#Post-Acute Conditions#acute Covid
·nih.gov·
SARS-CoV-2 can cause lasting damage to cells’ energy production
SARS-CoV-2 Delta variant induces severe damages in the nasal cavity from the first day post-infection in the Syrian hamster model.
SARS-CoV-2 Delta variant induces severe damages in the nasal cavity from the first day post-infection in the Syrian hamster model.
“SARS-CoV-2 variant severe damages in the nasal cavity from the first day post-infection”
SARS-CoV-2 Delta variant induces severe damages in the nasal cavity from the first day post-infection
#nasal damage#acute Covid#Post-Acute Conditions#nose
·biorxiv.org·
SARS-CoV-2 Delta variant induces severe damages in the nasal cavity from the first day post-infection in the Syrian hamster model.