Found 710 bookmarks
Newest
R c15up
R c15up
·flip.it·
R c15up
Effectiveness of the 2023-to-2024 XBB.1.5 COVID-19 Vaccines Over Long-Term Follow-up: A Target Trial Emulation: Annals of Internal Medicine: Vol 0, No 0
Effectiveness of the 2023-to-2024 XBB.1.5 COVID-19 Vaccines Over Long-Term Follow-up: A Target Trial Emulation: Annals of Internal Medicine: Vol 0, No 0
“C-19 vaccines targeting the XBB.1.5 variant of Omicron were NOT effective in preventing infection and had relatively low VE against hospitalization and death, which declined rapidly over time."
·acpjournals.org·
Effectiveness of the 2023-to-2024 XBB.1.5 COVID-19 Vaccines Over Long-Term Follow-up: A Target Trial Emulation: Annals of Internal Medicine: Vol 0, No 0
Active surveillance of cats and dogs from households with human COVID-19 cases reveals over one quarter of pets infected with SARS-CoV-2 in 2020-2021 in Texas, United States
Active surveillance of cats and dogs from households with human COVID-19 cases reveals over one quarter of pets infected with SARS-CoV-2 in 2020-2021 in Texas, United States
“Active surveillance of cats and dogs from households with human COVID-19 cases reveals over one quarter of pets infected with SARS-CoV-2 in 2020-2021 in Texas, United States”
Active surveillance of cats and dogs from households with human COVID-19 cases reveals over one quarter of pets infected with SARS-CoV-2 in 2020-2021 in Texas, United States
·biorxiv.org·
Active surveillance of cats and dogs from households with human COVID-19 cases reveals over one quarter of pets infected with SARS-CoV-2 in 2020-2021 in Texas, United States
Elevated serum mtDNA in COVID-19 patients is linked to SARS-CoV-2 envelope protein targeting mitochondrial VDAC1, inducing apoptosis and mtDNA release
Elevated serum mtDNA in COVID-19 patients is linked to SARS-CoV-2 envelope protein targeting mitochondrial VDAC1, inducing apoptosis and mtDNA release
“These findings suggest that SARS-CoV-2 E-protein induces mitochondrial dysfunction, apoptosis, and mtDNA release via VDAC1 modulation. mtDNA that accumulates in the blood activates the cGAS-STING pathway, triggering inflammatory cytokine and chemokine expression that contribute to the cytokine storm and tissue damage”
These findings suggest that SARS-CoV-2 E-protein induces mitochondrial dysfunction, apoptosis, and mtDNA release via VDAC1 modulation. mtDNA that accumulates in the blood activates the cGAS-STING pathway, triggering inflammatory cytokine and chemokine expression that contribute to the cytokine storm and tissue damage
·link.springer.com·
Elevated serum mtDNA in COVID-19 patients is linked to SARS-CoV-2 envelope protein targeting mitochondrial VDAC1, inducing apoptosis and mtDNA release
COVID-19 Remains Major Health Threat in U.S.
COVID-19 Remains Major Health Threat in U.S.
continues to be a threat to America’s health, causing more illness and death than either influenza or respiratory syncytial virus (RSV), a new study suggests.COVID accounted for 3 of 5 (60%) respiratory illnesses among military veterans treated by the U.S. Veterans Health Administration during the 2023-2024 cold and flu season, researchers reported Jan. 27 in JAMA Internal Medicine.COVID also caused more deaths than either influenza or RSV during that period
·healthday.com·
COVID-19 Remains Major Health Threat in U.S.
Study links long COVID severity with white blood cell count
Study links long COVID severity with white blood cell count

“A simple blood test might determine which patients are at risk for long COVID, a new study says.

Higher levels of leukocytes -- a form of white blood cell -- are associated with more severe symptoms of long COVID among older women, researchers reported in a new study published Wednesday in the journal Menopause.”

·msn.com·
Study links long COVID severity with white blood cell count
SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3
SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3
“Senescent cells, which arise due to damage-associated signals, are apoptosis-resistant and can express a pro-inflammatory, tissue-destructive senescence-associated secretory phenotype (SASP). We recently reported that a component of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) surface protein, S1, can amplify the SASP of senescent cultured human cells”
Senescent cells, which arise due to damage-associated signals, are apoptosis-resistant and can express a pro-inflammatory, tissue-destructive senescence-associated secretory phenotype (SASP). We recently reported that a component of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) surface protein, S1, can amplify the SASP of senescent cultured human cells
·pmc.ncbi.nlm.nih.gov·
SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3