“Everyone is freaking out about measles because it's "the most contagious virus"... and measles is very dangerous. This concern is warranted, but our vaccines against it are extremely successful.
It has an RO of between 12 and 18.
That's how many people a single infected person can infect (and tbh this is a terrible system because it doesn't include modern rooms packed with people.)
When we were still tracking RO of COVID, it was sitting AROUND 12, and that was in 2022. This was at a point when it was steadily increasing.
So, we can assume it has increased since then.
COVID is just as infectious as Measles, but we vaccinate against Measles extremely well. Measles is also a more visible disease, which makes it easier to identify.
But in the end...
COVID causes much more death.
COVID causes blindness, hearing loss, and developmental delays just like Measles.
And we don't successfully vaccinate for COVID on a wide scale like we can for Measles.
There is no real difference between the folks saying getting Measles is normal and those saying getting COVID is normal.
The main difference though is that we have two millennia of tiny graves from Measles, and we've only just started the grave sites for dead kids from COVID.
Please vaccinate your children, and we need to push for Novavax access for kids... because every child under 12 is not properly vaccinated for COVID...
And this carries many of the same risks as a measles infection...
Kids don't even have access to the better vaccine.
So, for every bit of concern for kids unvaccinated for measles, there should be equal concern for every kid not properly vaccinated for COVID.
The mRNA vaccine simply does not create the safety the measles vaccine does for a virus that can cause almost equal but less visible damage.
Every kid under 12 and most kids in general are just as unvaccinated for COVID as these kids catching measles are, except the concern should be much larger because the outcomes are just as bad or worse, and it's far more children at risk.
Currently, all of our children are at risk.
And people clearly care about that level of risk, but they simply don't know it is present.”
“Intranasal protein vaccine with MF59-like adjuvant protects against SARS-CoV-2, including XBB variants.
In mice, it boosts mucosal immunity with durable neutralizing antibodies.”
PICOBOO randomized trial, evaluating second boosters after mRNA priming. 1) novavax is more durable 2) mRNA vaccines have higher antibody responses 3) novavax has fewer side effects
Pfizer antibody levels drop around 40% between 1 month to 3 months post vax. Moderna is less, w/ a 14% drop in younger adults, 26% decline in older adults. Novavax had only a 3% decline in younger adults and 17% in older adults.
A protein-based vaccine against SARS-CoV-2 has been developed.
It is based on the spike protein containing a modified receptor binding domain (cRBD) with a set of engineered mutations.
It provides broad protection against various SARS-CoV-2 variants.
“China's Wuhan lab accused of Covid leak develops intranasal vaccine to protect against all forms of coronavirus”
Study at KU Leuven on hamsters finds that immunity from XBB.1.5 COVID-19 vaccine favors the original strain, limiting antibody response to newer variants like JN.1.
Highlights the challenge of updating vaccines for evolving SARS-CoV-2.
While effective at preventing severe COVID-19, the protection you get from mRNA vaccines can fade within months.
Long-lasting immune cells that fight SARS-CoV-2 aren't usually found in mRNA-vaccinated people, unlike the immune cells for tetanus and flu.
“Is this the way COVID ends? Next-generation inhaled vaccines could be the key to ending pandemic Existing COVID-19 vaccines can prevent severe disease, but not infection. A new hope comes in the form of needle-free mucosal vaccines…
…Some see mucosal vaccines as the best hope to end the COVID-19 pandemic. They are now in development in labs around the world, including in Canada. The United States and other countries are investing heavily in the development of mucosal vaccines for COVID-19 and beyond.”
“I think anybody who tells you COVID-19 isn’t a surprise is not being truthful,” said Matthew Miller, who is co-director of the Canadian Pandemic Preparedness Hub, Canada Research Chair in Viral Pandemics and an associate professor in biochemistry at McMaster University in Hamilton. He is part of the research team that is developing an inhaled COVID-19 vaccine.
“I have studied pandemic viruses for a long time. I completely expected we would be in a place by now where COVID-19 was exhibiting seasonal trends (similar to influenza and other seasonal viruses that generally occur in the fall and winter). Clearly I was wrong.”
“A new study from researchers at the Mayo Clinic suggests that being vaccinated against COVID-19 does little to prevent long COVID.
The findings contradict what has become conventional wisdom in the last 3 years—that vaccines offer a chance to significantly reduce the risk of long COVID, or new or persistent symptoms 3 months or more after infection, most likely by reducing the severity of infection.
Melanie Swift, MD, MPH, was the lead author of the study, which was published in Open Forum Infectious Diseases. She said despite the current thinking that vaccines reduce the risk of developing long COVID, she wasn’t surprised she found no association.”
“Overhyping Vaccines Wasn’t Pro-Vaccine. It Was Pro-Stop-Worrying-About-COVID. Overselling the vaccine in 2021 was not being pro-vaccine. It was pro-stop-worrying-about-the pandemic, from the doctors who assured us herd immunity was imminent.”
We will never get this vaccine.
"The [live-attenuated intranasal] vaccine offers potent protection against transmission, prevents reinfection and the spread of the virus, while also reducing the generation of new variants."
So naturally we will never get it.
unlike limited and quickly waning efficacy of MRNA, “innovative vector vaccine developed at the Helmholtz Center for Infection Research (HZI) presents a compelling alternative. It elicits prolonged immune response in animal models, and maintains its efficacy over extended time.”
August, 2024: South Korea: COVID-19 vaccinations to resume amid surge in cases
"Just 4 months after fully shifting to endemic approach, gov’t scrambles to contain virus."
The Korea Times