SARS-CoV-2 Transmission From People Without COVID-19 Symptoms
59% of all transmission came pre/asymptomatic transmission,
35% presymptomatic individuals 24% asymptomatic.
SARS-CoV-2 variants induce increased inflammatory gene expression but reduced interferon responses and heme synthesis as compared with wild type strains
This study provides some insights into why some people remain asymptomatic when infected with SARS-CoV-2, particularly the newer variants
Spectrum of COVID-19 cases in Arkhangelsk, Northwest Russia: Findings from a population-based study linking serosurvey, registry data, and self-reports of symptoms | PLOS ONE
“After a year of the pandemic in Arkhangelsk, 59.7% 95% confidence intervals (CI) (56.7; 62.6) of the surveyed population had had COVID-19. Among those who had been infected, symptomatic cases comprised 47.1% 95% CI (43.2; 51.0), with 8.6% 95% CI (6.6; 11.1) of them having been hospitalized. Of the asymptomatic cases, 96.2% were not captured by the healthcare system. Older age was positively associated, while smoking showed a negative association with symptomatic COVID-19. Individuals older than 65 years, and those with poor self-rated health were more likely to be hospitalized. Conclusion More than half of the infected individuals were not captured by the healthcare-based registry, mainly those with asymptomatic infections.”
I'm on day 15 COVID + and I NEVER had a fever. Nor did my partner. COVID guidelines aren't prevention guides, they're "how to stay in a pandemic" playbook.
“I'm on day 15 COVID + and I NEVER had a fever. Nor did my partner.
@CDC COVID guidelines aren't prevention guides, they're ‘how to stay in a pandemic’ playbook.”