Covid General Articles, Discussions, Videos

Covid General Articles, Discussions, Videos

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Over 300 COVID outbreaks hit Alberta acute care facilities last year
Over 300 COVID outbreaks hit Alberta acute care facilities last year

“Thousands of patients and health care workers were infected during COVID-19 outbreaks in acute care facilities in Alberta in the last year, raising questions about why more isn’t being done to prevent in-hospital transmission… …’The reality is that people are dying from COVID in our hospitals, and we really are doing very little to prevent them getting ill and getting infected. And we wouldn't do the same for any other infectious disease,’”

Thousands of patients and health care workers were infected during COVID-19 outbreaks in acute care facilities in Alberta in the last year, raising questions about why more isn’t being done to prevent in-hospital transmission.
#Covid Statistics#hospital acquired infection
·stalbertgazette.com·
Over 300 COVID outbreaks hit Alberta acute care facilities last year
High Frequency of Prior Severe Acute Respiratory Syndrome Coronavirus 2 Infection by Sensitive Nucleocapsid Assays | The Journal of Infectious Diseases | Oxford Academic
High Frequency of Prior Severe Acute Respiratory Syndrome Coronavirus 2 Infection by Sensitive Nucleocapsid Assays | The Journal of Infectious Diseases | Oxford Academic
“In this study, we show that the Simoa serology assay and T-cell intracellular cytokine staining assay are more sensitive than the clinical Elecsys assay for detection of nucleocapsid-specific immune responses. These data suggest that the prevalence of prior SARS-CoV-2 infection in the population may be higher than currently appreciated.”
In this study, we show that the Simoa serology assay and T-cell intracellular cytokine staining assay are more sensitive than the clinical Elecsys assay for detection of nucleocapsid-specific immune responses. These data suggest that the prevalence of prior SARS-CoV-2 infection in the population may be higher than currently appreciated.
#nucleocapside#antibodies#antibody test#Simoa#Covid Statistics
·academic.oup.com·
High Frequency of Prior Severe Acute Respiratory Syndrome Coronavirus 2 Infection by Sensitive Nucleocapsid Assays | The Journal of Infectious Diseases | Oxford Academic
Review of infective dose, routes of transmission and outcome of COVID-19 caused by the SARS-COV-2: comparison with other respiratory viruses | Epidemiology & Infection | Cambridge Core
Review of infective dose, routes of transmission and outcome of COVID-19 caused by the SARS-COV-2: comparison with other respiratory viruses | Epidemiology & Infection | Cambridge Core

Higher doses of SarsCov2 at exposure correlate with higher viral loads and severe symptoms in animals.

The more virus you are exposed to the more severe your disease. (HINT: masks work to lower viral loads)

#transmission#viral load#masks#masks work
·cambridge.org·
Review of infective dose, routes of transmission and outcome of COVID-19 caused by the SARS-COV-2: comparison with other respiratory viruses | Epidemiology & Infection | Cambridge Core
“It is literally, actively killing me that people don’t mask. No one cares.”
“It is literally, actively killing me that people don’t mask. No one cares.”

“‘It is literally, actively killing me that people don’t mask. No one cares.’

Tinu died less than two months later. She spent her final days sounding the alarm, pleading for healthcare staff to take her safety seriously.

I fight for you, Tinu. I miss you.”

#Discussion#Mortality#anecdote#masks#Tinu Abayomi-Paul#activism#Advocacy#broken healthcare systems#masks in healthcare#Clean Air#RIP#inevitable effects of Forever Covid
·x.com·
“It is literally, actively killing me that people don’t mask. No one cares.”
Covid fell to 10th leading cause of death in the U.S. last year, down from 4th
Covid fell to 10th leading cause of death in the U.S. last year, down from 4th
“Whereas American Indian and Alaska Native people had the highest rate of Covid deaths during the pandemic, white people had the highest rate last year: nearly 20 out of every 100,000 people. “
Whereas American Indian and Alaska Native people had the highest rate of Covid deaths during the pandemic, white people had the highest rate last year: nearly 20 out of every 100,000 people.
#Covid Statistics#Mortality#analysis
·nbcnews.com·
Covid fell to 10th leading cause of death in the U.S. last year, down from 4th
Covid still a risk to vulnerable people - Essex matron says
Covid still a risk to vulnerable people - Essex matron says

“An NHS matron said that too often people were mistaking Covid for a common cold and a lack of testing could be putting vulnerable people at risk. Lana Goodwin, who works in Covid services at Mid and South Essex NHS Foundation Trust in Billericay, Essex, said she believed people who were not high risk ‘feel that Covid has gone.’…Ms Goodwin said that her clinic had people testing positive for the virus every day and vulnerable people were ‘unfortunately still dying from Covid.’”

An NHS matron said that too often people were mistaking Covid for a common cold and a lack of testing could be putting vulnerable people at risk.Lana Goodwin, who works in Covid services at Mid and South Essex NHS Foundation Trust in Billericay, Essex, said she believed people who were not high risk "feel that Covid has gone".
#risks#minimizing and outright propaganda#Covid Isn't Over
·bbc.com·
Covid still a risk to vulnerable people - Essex matron says
Do you still think the government has been transparent with you about SARS-CoV-2 (COVID-19) or H5N1 (bird flu, a subtype of influenza A found in nearly every animal species)?
Do you still think the government has been transparent with you about SARS-CoV-2 (COVID-19) or H5N1 (bird flu, a subtype of influenza A found in nearly every animal species)?
“You stopped masking when Biden said it was okay—but it never was. COVID never disappeared, never became ‘milder.’ It’s still spreading to brains, seeding reservoirs in bone marrow, and altering lives permanently. You believe it all started with a bat at a wet market? Natural, huh? Even though the Wuhan lab studying coronaviruses was only 280 meters from the alleged outbreak site? Face it: U.S. research collaborations were involved. What killed your friends, disabled you, and affected your pets was engineered in a lab. No wonder they’d cover it up.”
#Discussion#Sean Mullen#media and government lies#minimizing and outright propaganda#Joe Biden
·x.com·
Do you still think the government has been transparent with you about SARS-CoV-2 (COVID-19) or H5N1 (bird flu, a subtype of influenza A found in nearly every animal species)?
British gran fighting for life after getting Covid on 'dream' holiday
British gran fighting for life after getting Covid on 'dream' holiday

“A beloved British nan has been left fighting for her life in the USA after she caught Covid on a dream trip she spent more than two years saving up for.

Patricia Bunting, 76, is currently bedbound and unresponsive in a critical care unit in Orlando, Florida, after contracting the virus during what was supposed to be a joyful final trip abroad with her sons and grandson.”

A beloved British nan has been left fighting for her life in the USA after she caught Covid on a dream trip she spent more than two years saving up for. Patricia Bunting, 76, is currently bedbound and unresponsive in a critical care unit in Orlando, Florida, after contracting the virus during what was supposed to be a joyful final trip abroad with her sons and grandson.
·mirror.co.uk·
British gran fighting for life after getting Covid on 'dream' holiday
Comprehensive method for producing high-affinity mouse monoclonal antibodies of various isotypes against (4-hydroxy-3-nitrophenyl)acetyl (NP) hapten
Comprehensive method for producing high-affinity mouse monoclonal antibodies of various isotypes against (4-hydroxy-3-nitrophenyl)acetyl (NP) hapten

New protocol from Japan enables high-affinity monoclonal antibody production from single B cells in 6 days.

Cost-effective and works across antibody types, including for SARS-CoV-2 spike protein.

#Monoclonal Antibodies#early treatment#treatment#protocols
·cell.com·
Comprehensive method for producing high-affinity mouse monoclonal antibodies of various isotypes against (4-hydroxy-3-nitrophenyl)acetyl (NP) hapten
For the love of God, Covid isn't over - so can people please wear masks?
For the love of God, Covid isn't over - so can people please wear masks?
“I want to use this piece to spark a debate about who we are as people. Are we kind and virtuous, or are we selfish and indifferent? Writing an article about what stops people from wearing masks, while I live with the pain caused by my wife not masking, feels like an oddly meta activity.”
I want to use this piece to spark a debate about who we are as people. Are we kind and virtuous, or are we selfish and indifferent? Writing an article about what stops people from wearing masks, while I live with the pain caused by my wife not masking, feels like an oddly meta activity.
#masks#Discussion#anecdote
·thecanary.co·
For the love of God, Covid isn't over - so can people please wear masks?
COVID Dystopia: Semi Finalist at Serbest International Film Festival – Analog Artist Digital World
COVID Dystopia: Semi Finalist at Serbest International Film Festival – Analog Artist Digital World
“COVID Dystopia was a Semi – Finalist at the Serbest International Film Festival. That means the jury liked the film but would not dare to show it to an audience”
COVID Dystopia was a Semi – Finalist at the Serbest International Film Festival. That means the jury liked the film but would not dare to show it to an audience
#Covid effects on the arts#covid reflected in the arts#Covid represented in art#films
·analogartistdigitalworld.com·
COVID Dystopia: Semi Finalist at Serbest International Film Festival – Analog Artist Digital World
Golgi-derived extracellular vesicle production induced by SARS-CoV-2 envelope protein
Golgi-derived extracellular vesicle production induced by SARS-CoV-2 envelope protein
“Extracellular vesicles facilitate cell-to-cell communication, and some enveloped viruses utilize these vesicles as carriers to mediate viral transmission. SARS-CoV-2 envelope protein (2-E) forms a cation channel and overexpression of 2-E led to the generation of a distinct type of large extracellular vesicles (2-E-EVs). Although 2-E-EVs have been demonstrated to facilitate viral transmission in a receptor-independent way, the characteristics and biogenesis mechanism remain enigmatic.”
Extracellular vesicles facilitate cell-to-cell communication, and some enveloped viruses utilize these vesicles as carriers to mediate viral transmission. SARS-CoV-2 envelope protein (2-E) forms a cation channel and overexpression of 2-E led to the generation of a distinct type of large extracellular vesicles (2-E-EVs). Although 2-E-EVs have been demonstrated to facilitate viral transmission in a receptor-independent way, the characteristics and biogenesis mechanism remain enigmatic.
#Golgi-derived extracellular vesicle production#Extracellular vesicles#transmission
·link.springer.com·
Golgi-derived extracellular vesicle production induced by SARS-CoV-2 envelope protein
It doesn't get much more macho or conservative than the Marines. Nice of them to demonstrate even cotton masks reduce disease transmission in November 2024.
It doesn't get much more macho or conservative than the Marines. Nice of them to demonstrate even cotton masks reduce disease transmission in November 2024.

“It doesn't get much more macho or conservative than the Marines. Nice of them to demonstrate even cotton masks reduce disease transmission in November 2024.

They require masks in Phase 1, because they have new recruits gathered together.”

#masks#marines#mask mandate#Video#analysis#Discussion#Lazarus Long
·x.com·
It doesn't get much more macho or conservative than the Marines. Nice of them to demonstrate even cotton masks reduce disease transmission in November 2024.
MCRDSD Graduation Program
MCRDSD Graduation Program

“All personnel must wear a mask while indoors at the Branch Medical Clinic and the Branch Dental Clinic.

All Recruits must wear masks during Phase 1 of Recruit Training.”

All personnel must wear a mask while indoors at the Branch Medical Clinic and the Branch Dental Clinic. All Recruits must wear masks during Phase 1 of Recruit Training.
#marines#mask mandate#masks
·mcrdsd.marines.mil·
MCRDSD Graduation Program
Covid-19 may lead to longest period of peacetime excess mortality, says new Swiss Re report | Swiss Re
Covid-19 may lead to longest period of peacetime excess mortality, says new Swiss Re report | Swiss Re

“Report suggests potential excess mortality in the general population of up to 3% for the US by 2033 and 2.5% in the UK, the longest period of elevated peacetime excess mortality in the US Key driver of excess mortality is the lingering impact of COVID-19; both as a direct cause of death, and as a contributor to cardiovascular mortality”

Report suggests potential excess mortality in the general population of up to 3% for the US by 2033 and 2.5% in the UK, the longest period of elevated peacetime excess mortality in the US Key driver of excess mortality is the lingering impact of COVID-19; both as a direct cause of death, and as a contributor to cardiovascular mortality
·swissre.com·
Covid-19 may lead to longest period of peacetime excess mortality, says new Swiss Re report | Swiss Re
Discovery of orally bioavailable SARS-CoV-2 papain-like protease inhibitor as a potential treatment for COVID-19
Discovery of orally bioavailable SARS-CoV-2 papain-like protease inhibitor as a potential treatment for COVID-19

Chinese researchers:

GZNL-P36 is a promising drug candidate for COVID-19 targeting a conserved viral enzyme, showing broad antiviral and anti-inflammatory effects.

Mouse trials: it reduces viral load, inflammation, and lung damage

#treatment#antiviral#GZNL-P36#papain-like protease inhibitor#protease inhibitors
·nature.com·
Discovery of orally bioavailable SARS-CoV-2 papain-like protease inhibitor as a potential treatment for COVID-19
U.S. May See A Healthy Thanksgiving—But Covid, RSV Could Spike Before Christmas, CDC Warns
U.S. May See A Healthy Thanksgiving—But Covid, RSV Could Spike Before Christmas, CDC Warns

November 22, 2024 “On Wednesday, the CDC warned it expects to see an increase in Covid and RSV levels in the coming weeks as large gatherings, travel and more time indoors allow disease to spread more easily person-to-person. The CDC recommends opening windows and doors for ventilation, wearing masks in crowded areas, practicing regular handwashing and being up-to-date on Covid and flu vaccinations to avoid getting sick. “

On Wednesday, the CDC warned it expects to see an increase in Covid and RSV levels in the coming weeks as large gatherings, travel and more time indoors allow disease to spread more easily person-to-person. The CDC recommends opening windows and doors for ventilation, wearing masks in crowded areas, practicing regular handwashing and being up-to-date on Covid and flu vaccinations to avoid getting sick.
#Covid Statistics#CDC
·forbes.com·
U.S. May See A Healthy Thanksgiving—But Covid, RSV Could Spike Before Christmas, CDC Warns
Flu and COVID-19 cases continue to climb in Arizona
Flu and COVID-19 cases continue to climb in Arizona

Nov 22, 2024: “Respiratory viruses continue to spread in Arizona. The Arizona Department of Health Services reported more than 1,000 cases of influenza last week and more than 2,100 cases of COVID-19.

Respiratory viruses continue to spread in Arizona. The Arizona Department of Health Services reported more than 1,000 cases of influenza last week and more than 2,100 cases of COVID-19.
#Covid Statistics#influenza
·kjzz.org·
Flu and COVID-19 cases continue to climb in Arizona
I was a music journalist for years and have been going to gigs for over 20 years and the amount of tour cancellations is unprecedented
I was a music journalist for years and have been going to gigs for over 20 years and the amount of tour cancellations is unprecedented
“I was a music journalist for years and have been going to gigs for over 20 years and the amount of tour cancellations is unprecedented”
#Anecdote#superspreader#musicians with Covid#Covid effects on the arts#inevitable effects of Forever Covid#Discussion
·x.com·
I was a music journalist for years and have been going to gigs for over 20 years and the amount of tour cancellations is unprecedented
If anyone thinks musicians dropped like this before covid they are lying to themselves
If anyone thinks musicians dropped like this before covid they are lying to themselves
“Bieber cancelling his tour due to long covid complications, Harry Styles recently cancelling shows due to covid and now Springsteen cancelling shows just 3 weeks into their world tour, 2023 will be the year touring musicians show us there is no return to normal with endemic covid”
#musicians with Covid#Covid effects on the arts#inevitable effects of Forever Covid#Long Covid#Post-Acute Conditions#acute Covid#superspreader#Nate Bear
·x.com·
If anyone thinks musicians dropped like this before covid they are lying to themselves
An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo
An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo

Researchers at The University of Hong Kong developed TMP1, an oral drug blocking coronavirus entry and replication.

Tested in mice and hamsters, it was effective against SARS-CoV-2 variants and drug-resistant strains.

#antiviral#Treatment#Mpro/TMPRSS2 bispecific inhibitor
·researchsquare.com·
An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo