“The most serious symptom is the potential for sudden, acute respiratory failure in individuals who may have previously only experienced mild to moderate symptoms.. Someone can appear to be recovering and suddenly face a rapid decline, often due to microvascular complications in the lungs, leading to severe oxygen deprivation.."
“Every one of these subvariants is distinct enough that a whole swathe of people are no longer immune to it and it can infect them. That’s why you see this constant undulatory pattern which doesn’t look seasonal at all,” he says. Adding in seasonal factors, such as cooler weather forcing people indoors and children returning to school, and the conditions are frequently conducive to a new wave.”
“SARS-CoV-2, the virus that causes COVID-19, can cause lasting damage to energy production by mitochondria in many organs of the body. Stopping the virus from hijacking mitochondrial energy production may be a novel way to prevent serious complications from SARS-CoV-2 infection.”
“After a year of the pandemic in Arkhangelsk, 59.7% 95% confidence intervals (CI) (56.7; 62.6) of the surveyed population had had COVID-19. Among those who had been infected, symptomatic cases comprised 47.1% 95% CI (43.2; 51.0), with 8.6% 95% CI (6.6; 11.1) of them having been hospitalized. Of the asymptomatic cases, 96.2% were not captured by the healthcare system. Older age was positively associated, while smoking showed a negative association with symptomatic COVID-19. Individuals older than 65 years, and those with poor self-rated health were more likely to be hospitalized. Conclusion More than half of the infected individuals were not captured by the healthcare-based registry, mainly those with asymptomatic infections.”
“If you were comfortable with catching it and spreading it, you were comfortable with killing people.
At no point in this ongoing pandemic did Covid stop killing people.”
“this study investigated the airborne transmission of respiratory diseases in the hospital elevator by comparison to the conference room.”
“The results showed that the infection probability in the elevator with 5 min was higher than that in the conference room with 50 min.”
Anti-Viral Impact of Metformin “When AMPK was activated in Calu3 and Caco2 cell lines using metformin, there was a remarkable suppression of SARS-CoV-2 infectious titers, with up to 99% reduction observed in infected cells.”
Metformin suppresses SARS-CoV-2 in cell culture
“Just so people reading this know:
When you have covid, you exhale covid particles into the air. Even with just ordinary breathing.
Those particles can then float on the air for hours.”
"It [pandemic} wasn't over. It still isn't over."
Nurse who nearly died from Covid sues NHS for negligence.
Rebecca Firth, 42, is seeking damages from the NHS.
She spent 21 days in the ICU, a month on a ventilator, suffered 3 cardiac arrests, sepsis & multiple organ failure as a result of COVID.
“It's been ~5yrs since 𝑆𝐀𝑅𝑆-𝐂𝑂𝑉-𝟐, the virus that causes 𝐂𝑂𝑉𝐈𝐃, made its fateful jump into humans. Now seems as good a time as any to ask "is it over yet?" (For the 10th time, but who's counting?)
Let's talk about how this ends, shall we? (1/)
“data piles up that #LongCovid harms the workforce (esp in healthcare, education too), WHERE ARE THE UNIONS?
Dire shortages are worsened by govt’s refusal to provide clean air to ASHRAE 241 standards & laissez-faire approach to infections.
Unions need to GET LOUD, pronto. 🧵:
“I’m only a GP. And I’m shocked at how some of my specialist colleagues think they are not harming patients by not masking.
I’m not smart. But come on! Covid is airborne and Covid HARMS every bit of your body. How can a highly intelligent Dr NOT KNOW THIS???”
Next generation medicines in fight against Covid:
Focusing specifically on the receptor-binding domain (RBD) rather than the entire SARS-CoV-2 spike protein provides enhanced, long-lasting protection against viral mutations
“At the peak of the late-summer Covid wave, U.S. health systems were testing approximately evenly for COVID, flu, & RSV.
Yet, nearly all positive cases were Covid.
“Is this the way COVID ends? Next-generation inhaled vaccines could be the key to ending pandemic Existing COVID-19 vaccines can prevent severe disease, but not infection. A new hope comes in the form of needle-free mucosal vaccines…
…Some see mucosal vaccines as the best hope to end the COVID-19 pandemic. They are now in development in labs around the world, including in Canada. The United States and other countries are investing heavily in the development of mucosal vaccines for COVID-19 and beyond.”
“I think anybody who tells you COVID-19 isn’t a surprise is not being truthful,” said Matthew Miller, who is co-director of the Canadian Pandemic Preparedness Hub, Canada Research Chair in Viral Pandemics and an associate professor in biochemistry at McMaster University in Hamilton. He is part of the research team that is developing an inhaled COVID-19 vaccine.
“I have studied pandemic viruses for a long time. I completely expected we would be in a place by now where COVID-19 was exhibiting seasonal trends (similar to influenza and other seasonal viruses that generally occur in the fall and winter). Clearly I was wrong.”
“How is COVID-19 spread? When people cough, sneeze or talk, viral particles can be sent through the air and via droplets. Masking helps to prevent droplet spread, and keeping more than two metres apart and staying in a well-ventilated area can help to limit aerosol spread.
While not a predominant cause of transmission, COVID-19 can also be spread through objects contaminated with secretions from an infected person. The incubation period for COVID-19 — the time from exposure to developing an infection — is about two to four days with the current variant.”
