With little fanfare, Biden administration stacked vaccine advisory committee with new members
Covid General Articles, Discussions, Videos
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Unlike Chloroquine, Mefloquine Inhibits SARS-CoV-2 Infection in Physiologically Relevant Cells
Evidence from whole genome sequencing of aerosol transmission of SARS-CoV-2 almost 5 hours after hospital room turnover
“Airborne SARS-CoV-2 may transmit infection after more than 4 hours.”
Experimental evidence suggests that Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) remains viable within aerosols with a half-life of approximately 3 hours; however, it remains unclear how long airborne SARS-CoV-2 can transmit infection. Whole genome sequencing during an outbreak suggested in-room transmission of SARS-CoV-2 to two patients admitted nearly 2 and 5 hours, respectively, after discharge of an asymptomatic infected patient. These findings suggest that airborne SARS-CoV-2 may transmit infection for over 4 hours, even in a hospital setting.
‘Unacceptable’: Covid runs rampant in Aussie aged care facilities
Unacceptable’: Doctors raise alarm as Covid runs rampant in Aussie aged care facilities
Americans Still Consider COVID Major Public Health Threat
Inactivated SARS-CoV-2 induces acute skeletal muscle damage in human K18-hACE2 transgenic mice
Elevated serum mtDNA in COVID-19 patients is linked to SARS-CoV-2 envelope protein targeting mitochondrial VDAC1, inducing apoptosis and mtDNA release
“These findings suggest that SARS-CoV-2 E-protein induces mitochondrial dysfunction, apoptosis, and mtDNA release via VDAC1 modulation. mtDNA that accumulates in the blood activates the cGAS-STING pathway, triggering inflammatory cytokine and chemokine expression that contribute to the cytokine storm and tissue damage”
These findings suggest that SARS-CoV-2 E-protein induces mitochondrial dysfunction, apoptosis, and mtDNA release via VDAC1 modulation. mtDNA that accumulates in the blood activates the cGAS-STING pathway, triggering inflammatory cytokine and chemokine expression that contribute to the cytokine storm and tissue damage
The “pandemic of abandonment”: Navigating friendships five years into COVID-19 - The Sick Times
Study: Air purifier use at daycare centres cut kids' sick days by a third | Yle News | Yle
“Use of air purifiers at two daycare centres in Helsinki led to a reduction in illnesses and absences among children and staff, according to preliminary findings of a new study led by E3 Pandemic Response.”
‘Quad-demic’ Hitting US With Flu, COVID-19, RSV, Norovirus Surging
“The Centers for Disease Control and Prevention Respiratory Virus Activity Levels website shows that COVID-19, influenza A and respiratory syncytial virus have all been on the upswing since November.”
Surveillance tool can detect fast-spreading SARS-CoV-2 variants before they take off
Couples help researchers discover gene that may afford protection against COVID-19
COVID-19 Remains Major Health Threat in U.S.
continues to be a threat to America’s health, causing more illness and death than either influenza or respiratory syncytial virus (RSV), a new study suggests.COVID accounted for 3 of 5 (60%) respiratory illnesses among military veterans treated by the U.S. Veterans Health Administration during the 2023-2024 cold and flu season, researchers reported Jan. 27 in JAMA Internal Medicine.COVID also caused more deaths than either influenza or RSV during that period
How covid contributed to a crisis of trust in America
Covid inquiry live: Kemi Badenoch and Nadhim Zahawi giving evidence
What to Know About the CIA's Conclusion that COVID-19 Came From a Lab
Study links long COVID severity with white blood cell count
“A simple blood test might determine which patients are at risk for long COVID, a new study says.
Higher levels of leukocytes -- a form of white blood cell -- are associated with more severe symptoms of long COVID among older women, researchers reported in a new study published Wednesday in the journal Menopause.”
WATCH: RFK Jr. commits to prioritizing funding for long COVID research
SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3
“Senescent cells, which arise due to damage-associated signals, are apoptosis-resistant and can express a pro-inflammatory, tissue-destructive senescence-associated secretory phenotype (SASP). We recently reported that a component of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) surface protein, S1, can amplify the SASP of senescent cultured human cells”
Senescent cells, which arise due to damage-associated signals, are apoptosis-resistant and can express a pro-inflammatory, tissue-destructive senescence-associated secretory phenotype (SASP). We recently reported that a component of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) surface protein, S1, can amplify the SASP of senescent cultured human cells
VA study shows COVID more severe than RSV, flu | CIDRAP
“VA study shows COVID more severe than RSV, flu”
Some U.S. COVID-19 data are down amid “pause” to federal health communications - The Sick Times
“Some U.S. COVID-19 data are down amid “pause” to federal health communications”
SARS-CoV-2 cellular coinfection is limited by superinfection exclusion.
The 1st hour after SarsCov2 infection is the most vulnerable window for potential coinfection of already infected cells…?
Surveillance of SARS‐CoV‐2 in Pets of Harris County, Texas, Revealed More Common Pet Infections in Households With Human COVID‐19 Cases
Surveillance of SARS-CoV-2 in Pets of Harris County, Texas, Revealed More Common Pet Infections in Households With Human COVID-19 Cases
COVID, Flu, and RSV: Which Virus Has the Worst Outcomes?
“COVID, Flu, and RSV: Which Virus Has the Worst Outcomes? — COVID-19 still worse, but differences narrowed in 2023-2024 season compared with prior year”
CDC Ordered to Halt WHO Collaboration: What It Means for Infection Prevention and Global Health
“CDC Ordered to Halt WHO Collaboration: What It Means for Infection Prevention and Global Health”
CDC ordered to stop working with WHO immediately, upending expectations of an extended withdrawal
This breaks protocol which requires the approval of Congress and a one-year notice to leave the WHO.
Ultraviolet radiation vs air filtration to mitigate virus laden aerosol in an occupied clinical room
“Ultraviolet radiation vs air filtration to mitigate virus laden aerosol in an occupied clinical room”
Ultraviolet radiation vs air filtration to mitigate virus laden aerosol in an occupied clinical room
SARS-CoV-2 mRNA vaccine-related myocarditis and pericarditis: An analysis of the Japanese Adverse Drug Event Report database - PubMed
“In the Japanese population, SARS-CoV-2 mRNA vaccination was significantly associated with the onset of myocarditis/pericarditis. The influencing factors included age of ≤30 years and male. Furthermore, although most adverse events occurred early after vaccination, overall outcomes were good.”
In the Japanese population, SARS-CoV-2 mRNA vaccination was significantly associated with the onset of myocarditis/pericarditis. The influencing factors included age of ≤30 years and male. Furthermore, although most adverse events occurred early after vaccination, overall outcomes were good.
NEW: Columbia University leadership is considering banning masks on campus.