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One big, very basic issue is that most docs don't know what bird flu/avian flu/hpai is and that it's an Influenza A
One big, very basic issue is that most docs don't know what bird flu/avian flu/hpai is and that it's an Influenza A

“One big, very basic issue is that most docs don't know what bird flu/avian flu/hpai is and that it's an Influenza A

So then it can't even cross their mind to consider HPAI if they get a flu A+ patient

Add to that fact that many are not aware of the growing h5n1 issue.”

·x.com·
One big, very basic issue is that most docs don't know what bird flu/avian flu/hpai is and that it's an Influenza A
⚠️BREAKING
⚠️BREAKING

“December 26, 2024: BREAKING

H5N1 D1.1 is adapting to humans.

There are now two CRITICAL cases BOTH with multiple human adaptive mutations (BC teen,Louisiana case). A BirdFlu pandemic is coming our way.”

·x.com·
⚠️BREAKING
A few thoughts on public health risks ahead🧵👇: Since my story on US govt's botched response last month, things have gotten worse: 616 dairy herds in 15 states infected; 53 human cases including today's news of a child /1
A few thoughts on public health risks ahead🧵👇: Since my story on US govt's botched response last month, things have gotten worse: 616 dairy herds in 15 states infected; 53 human cases including today's news of a child /1
“A few thoughts on public health risks ahead🧵👇: Since my @VanityFair story on US govt's botched #H5N1 response last month, things have gotten worse: 616 dairy herds in 15 states infected; 53 human cases including today's news of a child”
·x.com·
A few thoughts on public health risks ahead🧵👇: Since my story on US govt's botched response last month, things have gotten worse: 616 dairy herds in 15 states infected; 53 human cases including today's news of a child /1
They’ll be testing to see if the H5N1 virus in the BC teen is binding the sialic acid-α2,6-galactose (SAα2,6Gal) receptor with high affinity. If so, the leap necessary for efficient human to human has been made.
They’ll be testing to see if the H5N1 virus in the BC teen is binding the sialic acid-α2,6-galactose (SAα2,6Gal) receptor with high affinity. If so, the leap necessary for efficient human to human has been made.

“They’ll be testing to see if the H5N1 virus in the BC teen is binding the sialic acid-α2,6-galactose (SAα2,6Gal) receptor with high affinity. If so, the leap necessary for efficient human to human has been made.

In order for efficient H-H transmission of avian viruses there needs to be a change from preferential recognition by the virus hemagglutinin of α2-3-sialyl-galactose-terminating host cell receptors, predominant in avian respiratory and gastrointestinal epithelia, to those terminating in α2-6-sialyl-galactose, which predominate in the human upper respiratory tract.”

·x.com·
They’ll be testing to see if the H5N1 virus in the BC teen is binding the sialic acid-α2,6-galactose (SAα2,6Gal) receptor with high affinity. If so, the leap necessary for efficient human to human has been made.