Long Covid/PASC (general)

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Immunoglobulin G Complexes from Post-infectious ME/CFS, including post-COVID ME/CFS Disrupt Cellular Energetics and Alter Inflammatory Marker Secretion
Immunoglobulin G Complexes from Post-infectious ME/CFS, including post-COVID ME/CFS Disrupt Cellular Energetics and Alter Inflammatory Marker Secretion
·sciencedirect.com·
Immunoglobulin G Complexes from Post-infectious ME/CFS, including post-COVID ME/CFS Disrupt Cellular Energetics and Alter Inflammatory Marker Secretion
Long COVID Defense Series II featuring 4 Virtual Q&A Sessions — Mask Together America
Long COVID Defense Series II featuring 4 Virtual Q&A Sessions — Mask Together America
400M people worldwide have #LongCOVID. Is it appropriate or excessive to routinely wear a close-fitting respirator in public for protection?  Prof. Iwasaki @VirusesImmunity said it makes sense to #MaskUp, get boosted and clean the air. Watch the forum:
·masktogetheramerica.org·
Long COVID Defense Series II featuring 4 Virtual Q&A Sessions — Mask Together America
Dual use of combustible and heated tobacco products associates persistent symptoms with a history of COVID-19: a JASTIS 2023 cross‑sectional study
Dual use of combustible and heated tobacco products associates persistent symptoms with a history of COVID-19: a JASTIS 2023 cross‑sectional study
“persistent symptoms were significantly elevated for four symptoms—arthralgia, chest pain, dyspnea, and dysosmia—compared to never smokers.”
·flip.it·
Dual use of combustible and heated tobacco products associates persistent symptoms with a history of COVID-19: a JASTIS 2023 cross‑sectional study
Metformin at the time of Covid-19 infection and risk of Long Covid: A Target Trial Emulation Study
Metformin at the time of Covid-19 infection and risk of Long Covid: A Target Trial Emulation Study

A new study finds that people on #metformin at the time of COVID-19 infection had a significantly lower risk of developing #LongCOVID.

➡️ Compared with non-users, metformin users saw a ~53% reduction in LongCOVID risk — a major drop, if confirmed.

·authorea.com·
Metformin at the time of Covid-19 infection and risk of Long Covid: A Target Trial Emulation Study
Long-COVID research just got a big funding boost: will it find new treatments?
Long-COVID research just got a big funding boost: will it find new treatments?

“the German government has announced that it will provide €500 million (US$582 million) in research funding to support a National Decade Against Post-Infectious Diseases from 2026 to 2036.. Germany is one of many countries facing an unprecedented health burden owing to long COVID and other post-infection syndromes since the COVID-19 pandemic.. Almost one in five people in a German cohort had long COVID in 2022.. The German government aims to fund research into a wide variety of post-infectious diseases, including Long COVID and ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome).."

·nature.com·
Long-COVID research just got a big funding boost: will it find new treatments?
Don't accept an incomplete and nonspecific diagnosis any longer, of just:
Don't accept an incomplete and nonspecific diagnosis any longer, of just:

“Don't accept an incomplete and nonspecific diagnosis any longer, of just: Long COVID Take the next step in identifying if your symptoms are due to tissue Hypoxia (associated with persistent endotheliitis)= hLC. We have simplified how to make this diagnosis, using the HHM Test Questionnaire, which you can answer from home. It only takes a few minutes:”

·x.com·
Don't accept an incomplete and nonspecific diagnosis any longer, of just:
Exploring predictors of post-COVID-19 condition among 810 851 individuals in Sweden
Exploring predictors of post-COVID-19 condition among 810 851 individuals in Sweden
“In this large population-based cohort study, our exploratory analysis reveals several risk factors for being diagnosed with PCC. Our findings can serve as a basis for future targeting of preventive measures against PCC.”
·flip.it·
Exploring predictors of post-COVID-19 condition among 810 851 individuals in Sweden
Immunological associations in post-infective fatigue syndromes including Long COVID—a systematic review and meta-analysis
Immunological associations in post-infective fatigue syndromes including Long COVID—a systematic review and meta-analysis
“These findings provide cautious support for persistent immune activation in PIFS, but warrant further replication. Future studies should include better documentation of acute infection and PIFS case characterisation.”
·flip.it·
Immunological associations in post-infective fatigue syndromes including Long COVID—a systematic review and meta-analysis
Beyond all reason
Beyond all reason
“Long COVID patients are constantly harangued about our requests for COVID safety. Yet what we're asking for is far less than what we're called on to do to survive.”ju
·thegauntlet.news·
Beyond all reason
Long COVID in a highly vaccinated but largely unexposed Australian population following the 2022 SARS‐CoV‐2 Omicron wave: a cross‐sectional survey
Long COVID in a highly vaccinated but largely unexposed Australian population following the 2022 SARS‐CoV‐2 Omicron wave: a cross‐sectional survey
"56% of Australians suffering from long COVID still had persistent symptoms 6 months after their initial infection, according to a new study from the Australian National University (ANU)"
·onlinelibrary.wiley.com·
Long COVID in a highly vaccinated but largely unexposed Australian population following the 2022 SARS‐CoV‐2 Omicron wave: a cross‐sectional survey
Factors associated with persistence or recovery from long COVID 6 months post-SARS-CoV-2 infection | Epidemiology & Infection | Cambridge Core
Factors associated with persistence or recovery from long COVID 6 months post-SARS-CoV-2 infection | Epidemiology & Infection | Cambridge Core
"56% of Australians suffering from long COVID still had persistent symptoms 6 months after their initial infection, according to a new study from the Australian National University (ANU)"
·cambridge.org·
Factors associated with persistence or recovery from long COVID 6 months post-SARS-CoV-2 infection | Epidemiology & Infection | Cambridge Core
Thread by @cbarbermd on Thread Reader App
Thread by @cbarbermd on Thread Reader App

Potential Long Covid treatment: “About 6 weeks ago, he started Dr. Skip Pridgen’s antiviral protocol: Valtrex, Celebrex & Paxlovid.”

About 6 weeks ago, he started Dr. Skip Pridgen’s antiviral protocol: Valtrex, Celebrex & Paxlovid.
·threadreaderapp.com·
Thread by @cbarbermd on Thread Reader App
Soluble IL‐2R: A potential therapeutic target for mitochondrial dysfunction in post‐COVID fatigue syndrome
Soluble IL‐2R: A potential therapeutic target for mitochondrial dysfunction in post‐COVID fatigue syndrome

Kentucky researchers studied 11 people with post-COVID fatigue and 17 healthy adults.

They found a five-log rise in soluble IL-2 receptor levels that directly damaged muscle mitochondria, suggesting a new drug target for long COVID fatigue.

·onlinelibrary.wiley.com·
Soluble IL‐2R: A potential therapeutic target for mitochondrial dysfunction in post‐COVID fatigue syndrome