“Histamine levels in alcoholic beverages may be underlying lower alcohol sales. Many individuals with Long Covid develop MCAS, where mast cells release excessive histamine and other inflammatory mediators, leading to symptoms like flushing, itching, headaches, and gastrointestinal issues. This can heighten sensitivity to histamine-rich foods and beverages, compounding histamine intolerance.”
Study in the US during the Omicron wave followed 248 metformin users over 6 months.
Starting metformin within a week of COVID reduced the risk of Long COVID or death by 53%.
Safe and inexpensive with results aligning with earlier data.
“Professional goalkeeper⚽️for West Ham, Sophie Hillyerd, contracted SARS-CoV-2 in September of 2021.
She developed Long COVID & autonomic issues because of it, which was ongoing at last a year later. She said it's like nothing she's ever experienced…” Thread:
UCSF study of 35 people with Long COVID had fewer mature NK cells 4 months after infection.
Lower NK cell levels linked to more symptoms like fatigue and brain fog.
NK cells clear infected cells, which may explain lasting symptoms.
“We hypothesize that the key to LC pathogenesis lies in the presence of chronic functional damage to the main anti-inflammatory mechanisms of our body:
“The three reflexes mediated by
“Physics Girl’s illness is marked by a range of debilitating symptoms that disrupt even the simplest aspects of daily life. She battles extreme fatigue, a persistent and overwhelming exhaustion that never seems to fade, no matter how much rest she gets. In addition, she suffers from severe brain fog, making it difficult to concentrate or perform basic cognitive tasks. Activities that once came naturally, such as researching scientific concepts or filming videos, now feel insurmountable. Moreover, she experiences sensory hypersensitivities to light, sound, and odors, which exacerbate her discomfort and limit her ability to engage with the world around her.
Dianna also experiences muscle pain and other physical limitations.”
“PASC patients showed differences in brain activation in fatigue-related and additional regions. • PASC patients also had increased frontal task-related activation compared to controls. • Findings suggest PASC patients may exert more mental effort during demanding tasks.”
“Vaccination prior to SARS-CoV-2 infection does not affect the neurologic manifestations of long COVID.
While vaccination decreases the severity of acute COVID infection, the sobering conclusion of our study is that vaccination prior to infection did not alter the subsequent neurologic manifestations of long COVID in our clinic population."
From a cohort of 172,303 in the UK, researchers found long COVID (PCC) has 4 subtypes: ENT (30.1%), cardiopulmonary (10.4%), neurological (23.5%), and fatigue (38%).
Vaccination lowered risks, and severe cases or multiple infections worsened outcomes.
Up to 70% of SARS-CoV-2 infected have reduced organ function for 4 months or more after infection, which leads to an increased risk of developing chronic diseases in e.g. lungs, kidneys and the cardiovascular system.
“Even though the etiology of COVID-19 is complex and there are multiple factors involved, decreased organ function has been associated with mitochondrial dysfunction for both the acute phase and post-acute phase of COVID”
“Between 2% and 14% of COVID survivors develop a syndrome called postural orthostatic tachycardia syndrome (POTS) (1).
However, it is commonly attributed to stress and anxiety.
This is the surprising story of how POTS (and possibly Long COVID) might be linked to an even rarer syndrome...🧵”
A vaccine that prevents tuberculosis & other mycobacterial infections as well as bladder cancer may prevent Long Covid.
A Phase 3 clinical trial found it decreased the likelihood of hearing/sleeping/concentration/memory/vision issues after COVID:
“Video art pieces name: ‘Trapped in Body and Time: Living the Reality of Severe ME/CFS and Long COVID’
This exhibition is especially meaningful because The Holy Art Gallery has a strong reputation and significant reach on social media, which means this piece has the potential to bring much-needed visibility to severe ME/CFS and Long COVID. I hope it helps amplify our voices.”
