Long Covid/PASC (general)

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The Gut-Centric Pathogenesis of Long COVID: A Synthesis of Mechanistic and Clinical Evidence Linking SARS-CoV-2, Microbiome Dysbiosis, and Post-Acute Sequelae
The Gut-Centric Pathogenesis of Long COVID: A Synthesis of Mechanistic and Clinical Evidence Linking SARS-CoV-2, Microbiome Dysbiosis, and Post-Acute Sequelae

The gastrointestinal tract is a central driver of Long COVID pathogenesis, w/ SARS-CoV-2 infecting intestinal cells and causing inflammation, microbiome dysbiosis, and more.

Persistent viral reservoirs in the gut lead to systemic and metabolic disruption.

#Viral Persistence#Gut microbiome#long covid#Post-Acute Conditions#microbiome
·davidlingenfelter.substack.com·
The Gut-Centric Pathogenesis of Long COVID: A Synthesis of Mechanistic and Clinical Evidence Linking SARS-CoV-2, Microbiome Dysbiosis, and Post-Acute Sequelae
A single-cell RNA sequencing dataset of peripheral blood cells in long COVID patients on herbal therapy
A single-cell RNA sequencing dataset of peripheral blood cells in long COVID patients on herbal therapy
New study shows Long Covid is marked by dendritic cell and monocyte dysfunction. Classic TCM formulas like Bu Zhong Yi Qi Tang & Tian Wang Bu Xin Dan may restore APC integrity & immune balance by modulating cytokines, Qi, & metabolism.
#Long Covid#Immune Dysregulation#blood cell#Traditional Chinese Medicine#Long Covid blood markers#Immune system#Cytokines#dendritic cells#monocyte dysfunction
·nature.com·
A single-cell RNA sequencing dataset of peripheral blood cells in long COVID patients on herbal therapy
Inside long COVID’s war on the body: Researchers are trying to find out whether the virus has the potential to cause cancer - Carolyn Barber
Inside long COVID’s war on the body: Researchers are trying to find out whether the virus has the potential to cause cancer - Carolyn Barber
“Extensive tissue damage, chronic inflammation, low levels of oxygen in the tissues, oxidative stress, impaired T-Cell responses, & elevated levels of cytokines are all mechanisms through which, it is postulated, SARS-CoV-2 may increase the risk of cancer development."
#Long Covid#cancer#Viral Persistence#organ damage#Immune system
·carolynbarbermd.com·
Inside long COVID’s war on the body: Researchers are trying to find out whether the virus has the potential to cause cancer - Carolyn Barber
Review of organ damage from COVID and Long COVID: a disease with a spectrum of pathology
Review of organ damage from COVID and Long COVID: a disease with a spectrum of pathology

Organ damage might affect over 50 % of post-COVID-19 individuals and perhaps more in adolescents and children.

Review of organ damage from COVID and Long COVID: a disease with a spectrum of pathology - PMC

#Long Covid#Post-Acute Conditions#consequences#organ damage#vascular#lung#KIdney#long covid#Heart#lungs#Kids
·pmc.ncbi.nlm.nih.gov·
Review of organ damage from COVID and Long COVID: a disease with a spectrum of pathology
Thread by @SalvMattera on Thread Reader App
Thread by @SalvMattera on Thread Reader App
“I continue to remain 90-95% recovered from my Long COVID. But what did I recover from? I went back through my symptom journals, and here's a list of all the Long COVID symptoms I had at one point then recovered from:”
I continue to remain 90-95% recovered from my Long COVID. But what did I recover from? I went back through my symptom journals, and here's a list of all the Long COVID symptoms I had at one point then recovered from:
#Long Covid#Post-Acute Conditions#Anecdote
·threadreaderapp.com·
Thread by @SalvMattera on Thread Reader App
Country legend opens up about health battle and treatment that changed her life
Country legend opens up about health battle and treatment that changed her life
“But it really messed with my smell and taste. I’d say I’m a longCOVID person. I had all the brain fog… people were like, 'You are in menopause,’ and I would be like, 'Yeah, but this is different because I’m looking at a rolling pin and I can’t name it.’”
#Long Covid#Post-Acute Conditions#Covid effects on the arts#musicians with Covid#brain abnormalities#brain fog#memory loss#working memory#cognitive decline#cognition#treatment#LENS Therapy#Trisha Yearwood
·the-express.com·
Country legend opens up about health battle and treatment that changed her life
Thread by @ffp34thewin on Thread Reader App
Thread by @ffp34thewin on Thread Reader App

“Famous people confirmed with Long COVID: Gwyneth Paltrow - Fatigue, brain fog Alyssa Milano - Shortness of breath, hair loss Colin Farrell - Headaches, temperature issues Dave Navarro - Ongoing fatigue Christina Applegate - Heart palpitations, dizziness (1/4)”

Famous people confirmed with Long COVID: Gwyneth Paltrow - Fatigue, brain fog Alyssa Milano - Shortness of breath, hair loss Colin Farrell - Headaches, temperature issues Dave Navarro - Ongoing fatigue Christina Applegate - Heart palpitations, dizziness (1/4)
#Long Covid#Post-Acute Conditions#compilations#Covid effects on the arts#musicians with Covid
·threadreaderapp.com·
Thread by @ffp34thewin on Thread Reader App
The SARS-CoV-2 trigger highlights host interleukin 1 genetics in Epstein-Barr virus reactivation
The SARS-CoV-2 trigger highlights host interleukin 1 genetics in Epstein-Barr virus reactivation

A new Czech study (Cell Reports, 2025): SARS-CoV-2 can trigger Epstein-Barr virus (EBV) reactivation - and in some people, that leads to long-term lung damage in long COVID.

#Post-Acute Conditions#EBV#Viral Persistence#Long Covid#reactivation of other viruses#lung#lung fibrosis#risks#Post-Acute Sequelae of COVID-19
·cell.com·
The SARS-CoV-2 trigger highlights host interleukin 1 genetics in Epstein-Barr virus reactivation