Novavax
“New RCT study shows the ‘conventional’ Novavax COVID vaccine has a similar side effect profile to the routine meningococcal vaccine, and fewer side effects than the mRNA options. Side effects are a leading cause of COVID vaccine hesitancy. This can help.”
Novavax data from South Korea 2022, 2 doses Novavax vs 3 doses of Pfizer.
Novavax - 19,485 infected within 6 months out of 104,004.
Pfizer - 10,445 infected out of 33,841, within 6 months. Severe infection was similar.
August, 2024
Excellent broad cross neutralization to variants with the upcoming JN.1 Novavax COVID vaccine, including some of the best responses to variants that are likely to be dominant this late fall and early winter
excellent explanation thread of differences between Novavax and MRNA vaccines.
“Novavax, likely because its stimulation method is slow and steady, instead of creating a hot and heavy pseudoinfection in your muscles like RNA, does not induce the IgG4 isotype switch. It instead generates more IgG3, with the most Fc effector function.”