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Multiomic characterisation of the long-term sequelae of SARS survivors: a clinical observational study
Multiomic characterisation of the long-term sequelae of SARS survivors: a clinical observational study
“Although health outcomes continued to improve, our study suggested that SARS survivors still suffered from physical fatigue, osteoporosis, and necrosis of the femoral head 18 years after discharge, possibly related to plasma metabolic disorders and immunological alterations.”
Although health outcomes continued to improve, our study suggested that SARS survivors still suffered from physical fatigue, osteoporosis, and necrosis of the femoral head 18 years after discharge, possibly related to plasma metabolic disorders and immunological alterations.
Fatigue was the most common symptom in SARS survivors 18 years after discharge, with osteoporosis and necrosis of the femoral head being the main sequelae. The respiratory function and hip function scores of the SARS survivors were significantly lower than those of the controls. Physical and social functioning at 18 years was improved compared to that after 12 years but still worse than the controls. Emotional and mental health were fully recovered. Lung lesions on CT scans remained consistent at 18 years, especially in the right upper lobe and left lower lobe lesions. Plasma multiomics analysis indicated an abnormal metabolism of amino acids and lipids, promoted host defense immune responses to bacteria and external stimuli, B-cell activation, and enhanced cytotoxicity of CD8+ T cells but impaired antigen presentation capacity of CD4+ T cells.
·thelancet.com·
Multiomic characterisation of the long-term sequelae of SARS survivors: a clinical observational study
Great British Bake Off in chaos as two contestants collapse and another quits
Great British Bake Off in chaos as two contestants collapse and another quits

“Great British Bake Off in chaos as two contestants collapse and another quits

Paul Hollywood asked ‘What the hell is going on?’ as the drama unfolded…

…It started with Jeff, a former university lecturer, who was suffering from illness during episode one’s ‘cake week’ and decided “I’ve had enough” in the latest episode…

…Speaking to presenter Alison Hammond, the 57-year-old said “I’m done” due to feeling unwell for a second week running. Consoling Jeff, Hammond said: “You tried man. You tried.”…

…31-year-old midwife Illiyin, who impressed the judges during episode one, told the crew she “felt a bit dizzy”, before being helped to the floor by medics and put in the recovery position…

…final drama came when Dylan fell off his chair - to which Essex car mechanic, Andy, exclaimed, “They’re dropping like flies!”

·independent.co.uk·
Great British Bake Off in chaos as two contestants collapse and another quits
I was an ableist asshole when I first became a teacher. Because that’s what I was taught! In my defense, academic institutions told me a strict attendance policy was required. What changed my perspective & my assessment criteria? Disabled students 🧵
I was an ableist asshole when I first became a teacher. Because that’s what I was taught! In my defense, academic institutions told me a strict attendance policy was required. What changed my perspective & my assessment criteria? Disabled students 🧵
“I was an ableist asshole when I first became a teacher. Because that’s what I was taught! In my defense, academic institutions told me a strict attendance policy was required. What changed my perspective & my assessment criteria? Disabled students 🧵”
·x.com·
I was an ableist asshole when I first became a teacher. Because that’s what I was taught! In my defense, academic institutions told me a strict attendance policy was required. What changed my perspective & my assessment criteria? Disabled students 🧵
U.S. ranks last in health care compared with nine other high-income countries, report finds
U.S. ranks last in health care compared with nine other high-income countries, report finds

“U.S. ranks last in health care compared with nine other high-income countries, report finds People in the U.S. die the youngest and experience the most avoidable deaths, despite spending nearly twice as much on health care as people in 10 developed countries.”

U.S. ranks last in health care compared with nine other high-income countries, report finds People in the U.S. die the youngest and experience the most avoidable deaths, despite spending nearly twice as much on health care as people in 10 developed countries.
·nbcnews.com·
U.S. ranks last in health care compared with nine other high-income countries, report finds