Medical

The cross-cultural study of alcohol represents a classic natural experiment: a single species (Homo Sapiens), a single drug substance (ethanol) and a great diversity of behavioural outcomes.

Lots of people are disabled but undiagnosed, so why don’t we ever hear stories about that experience?

During non–rapid eye movement sleep, low-frequency oscillations in neural activity support memory consolidation and neuronal computation. Sleep is also associated with increased interstitial fluid volume and clearance of metabolic waste products. It is unknown why these processes co-occur and how they are related. Fultz et al. simultaneously measured electrophysiological, hemodynamic, and flow signals in the human brain (see the Perspective by Grubb and Lauritzen). Large oscillations of fluid inflow to the brain appeared during sleep and were tightly coupled to functional magnetic resonance imaging signals and entrained to electroencephalogram slow waves. Slow oscillatory neuronal activity thus leads to oscillations in blood volume, drawing cerebrospinal fluid into and out of the brain. Science , this issue p. [628][1]; see also p. [572][2] Sleep is essential for both cognition and maintenance of healthy brain function. Slow waves in neural activity contribute to memory consolidation, whereas cerebrospinal fluid (CSF) clears metabolic waste products from the brain. Whether these two processes are related is not known. We used accelerated neuroimaging to measure physiological and neural dynamics in the human brain. We discovered a coherent pattern of oscillating electrophysiological, hemodynamic, and CSF dynamics that appears during non–rapid eye movement sleep. Neural slow waves are followed by hemodynamic oscillations, which in turn are coupled to CSF flow. These results demonstrate that the sleeping brain exhibits waves of CSF flow on a macroscopic scale, and these CSF dynamics are interlinked with neural and hemodynamic rhythms. [1]: /lookup/doi/10.1126/science.aax5440 [2]: /lookup/doi/10.1126/science.aaz5191

The synchronized brain waves of non-REM sleep may play a key role in preventing toxins from accumulating in a person's brain.

U-M researchers are seeing success with anti-aging drugs in the lab. Potential exists to postpone age-related diseases in humans and extend lifespan.

The American Migraine Foundation provides education, support and resources for the millions of men, women and children living with migraine.

Thirty years after scientists discovered the defective gene that causes cystic fibrosis, two new trials show a therapy could help 90 percent of patients. The FDA approved the triple drug, Trikafta, five months ahead of its deadline.

Ron Davis, a geneticist at Stanford, is one of our era's greatest inventors. Now, with his son ravaged by an incurable disease, Davis is leading a dream team of Nobel-winning scientists to find a cure.

Addiction exerts a long and powerful influence on the brain that manifests in three distinct ways: craving for the object of addiction, loss of control over its use, and continuing involvement with it despite adverse consequences. While overcoming ad...

A pilot study offers “a very promising start” in the effort to help people recover from traumatic brain injuries.

Old brains from people who didn't have dementia have much higher rates of neurogenesis than the brains of people with Alzheimer’s disease, the study found.

By David Tuller, DrPH Over the years, I’ve slammed U.S. medical and health care institutions that have championed the GET/CBT treatment paradigm for the illness or cluster of illnesses variously known as ME, CFS, ME/CFS or CFS/ME. I have done this both before and after the U.S. Centers for Disease Control and Prevent

Given these hurdles, it's hardly surprising that researchers hesitate to submit grant applications, or perhaps even move to entirely different fields.

Brown researchers find that different ALS-affected neurons degrade for different reasons in worm models.

Brain changes, visible on scans, are also associated with Alzheimer’s precursors

Younger hypothesized that because inflammation produces temperature increases, he could create a heat map of the brain

For decades, the medical community has ignored mountains of evidence to wage a cruel and futile war on fat people, poisoning public perception and ruining millions of lives. It's time for a new paradigm.

Researchers say depression can increase your risk for dementia. Here’s why and some simple steps you can take to reduce the odds.

Research into this debilitating disease has a rocky past. Now scientists may finally be finding their footing.

The decision ushers in what many experts believe will be a new era in treatment for people who suffer the most severe form of the headaches.

OMF Founder Linda Tannenbaum is the catalyst for increased ME/CFS research, renewing hope for millions of patients.

New research suggests that post-menopausal women who walk at an average pace for 40 minutes several times per week decrease risk of heart disease by 25 percent.

In Out of My Head, a filmmaker, seeking treatment for her daughter's migraine attacks, discovers a confounding neurological disease and learns why a devastating condition, afflicting nearly a billion people worldwide, remains so deeply misunderstood.

Find out how low dose naltrexone may help in fibromyalgia and chronic fatigue syndrome including doses, finding pharmacies and doctors, treatment regimens, side effects, patient stories and more.

Immune Effects of Low-dose Naltrexone in ME/CFS - Full Text View.

Almost two years after Dr. Collins announced that the NIH would reinvigorate ME/CFS, the NIH has finally provided funding for three research centers and one data center. - ProHealth.com

Griffith University, the home of the NCNED group in Australia, has produced a “groundbreaking” study. - ProHealth.com