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The percentage difference between the reported number of weekly or monthly deaths in 2020–2021 and the average number of deaths in the same period over the years 2015–2019. The reported number might not count all deaths that occurred due to incomplete coverage and delays in reporting.

The CDC had previously said that reporting rates of myocarditis for boys aged 16 to 17 could be more than 69 cases per million second doses administered and around 40 cases per million second doses in boys aged 12-15 years old. The CDC did not say whether it believes there is a link between the myocarditis cases and the vaccine, or disclose the rate of myocarditis in the age group without vaccination.

Before the emergence of more contagious coronavirus variants, estimates placed the threshold for herd immunity at between 60 to 70 percent of the population.

Sir Andrew Pollard, director of the Oxford Vaccine Group, said herd immunity is 'not a possibility' with the current Delta variant.

Review of the first batch of documents released by the FDA including the full scope of reported adverse events from Pfizer. Data collected was from the first 2.5 months of the public roll-out. The document was submitted to the FDA March 2021. Direct link to the FDA released document can be found in the report above. Full Document Released by the FDA can be found here:

The injured deserve healthcare! Where there's risk, there should be choice!

Background: Ivermectin is a drug that has been shown to be active against coronavirus disease 19 (COVID-19) in previous studies. Healthcare personnel are highly exposed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Therefore, ...

Abstract. The development of effective SARS-CoV-2 mRNA vaccines has been a significant accomplishment. Adverse events are extremely rare, but continued surveill

An ongoing outbreak of coronavirus disease 2019 (COVID-19) has spread around the world. It is debatable whether asymptomatic COVID-19 virus carriers a…

Nature Communications - Large-scale population screening can provide insights to levels of ongoing SARS-CoV-2 transmission. Here, the authors report a citywide screening of ~10,000,000 residents of...

Codon optimization describes the process used to increase protein production by use of alternative but synonymous codon changes. In SARS-CoV-2 mRNA vaccines codon optimizations can result in differential secondary conformations that inevitably affect a protein’s function with significant consequences to the cell. Importantly, when codon optimization increases the GC content of synthetic mRNAs, there can be an inevitable enrichment of G-quartets which potentially form G-quadruplex structures. The emerging G-quadruplexes are favorable binding sites of RNA binding proteins like helicases that inevitably affect epigenetic reprogramming of the cell by altering transcription, translation and replication. In this study, we performed a RNAfold analysis to investigate alterations in secondary structures of mRNAs in SARS-CoV-2 vaccines due to codon optimization. We show a significant increase in the GC content of mRNAs in vaccines as compared to native SARS-CoV-2 RNA sequences encoding the spike protein. As the GC enrichment leads to more G-quadruplex structure formations, these may contribute to potential pathological processes initiated by SARS-CoV-2 molecular vaccination.

Altom Maglio says his law firm in recent years has litigated more vaccine-related injury claims than any other in the United States.

This article examines issues related to COVID-19 inoculations for children. The bulk of the official COVID-19-attributed deaths per capita occur in th…

High COVID-19 vaccination rates were expected to reduce transmission of SARS-CoV-2 in populations by reducing the number of possible sources for transmission and thereby to reduce the burden of COVID-19 disease. Recent data, however, indicate that the epidemiological relevance of COVID-19 vaccinated individuals is increasing. In the UK it was described that secondary attack rates among household contacts exposed to fully vaccinated index cases was similar to household contacts exposed to unvaccinated index cases (25% for vaccinated vs 23% for unvaccinated).

Vaccination reduces the risk of delta variant infection and accelerates viral clearance. Nonetheless, fully vaccinated individuals with breakthrough infections have peak viral load similar to unvaccinated cases and can efficiently transmit infection in household settings, including to fully vaccinated contacts. Host–virus interactions early in infection may shape the entire viral trajectory.

In the USA and Germany, high-level officials have used the term pandemic of the unvaccinated, suggesting that people who have been vaccinated are not relevant in the epidemiology of COVID-19. Officials’ use of this phrase might have encouraged one scientist to claim that “the unvaccinated threaten the vaccinated for COVID-19”.1 But this view is far too simple.

All about COVID-19 vaccines including how to get vaccinations, searching for vaccination sites and vaccine type in Japan. Vaccinations are free of charge to anyone eligible.

The efforts from Japan's health authority offer stark contrast to coercive measures used in other countries.

At least 69 athletes collapse in one month, many dead |

Matthew Memoli favors vaccinations in vulnerable populations but argues population level vaccination could hinder the development of a natural, robust immunity gained through infection.

A Yale University doctor took aim at Dr. Anthony Fauci for the infectious disease expert’s dismissal of hydroxychloroquine as a potential treatment for COVID-19.

If the case that SARS2 originated in a lab is so substantial, why isn’t this more widely known? As is now obvious, there are many people who have reason not to talk about it.

The federal agency told a G.O.P. House member that it had notified EcoHealth Alliance, a group criticized for its U.S.-funded work with Wuhan scientists, to file data within five days.

The CDC admitted it has no record of an unvaccinated person spreading COVID after having previously recovered from the virus.

Moderna Therapeutics, the most highly valued private company in biotech, has run into troubling safety problems with its most ambitious therapy, STAT found.

CECC says approval of COVID vaccines for children under 12 will not be considered until 2nd dose issue settled | 2021-11-10 15:42:00

The world has bet the farm on vaccines as the solution to the pandemic, but the trials are not focused on answering the questions many might assume they are. Peter Doshi reports As phase III trials of covid-19 vaccines reach their target enrolments, officials have been trying to project calm. The US coronavirus czar Anthony Fauci and the Food and Drug Administration leadership have offered public assurances that established procedures will be followed.1234 Only a “safe and effective” vaccine will be approved, they say, and nine vaccine manufacturers issued a rare joint statement pledging not to prematurely seek regulatory review.5 But what will it mean exactly when a vaccine is declared “effective”? To the public this seems fairly obvious. “The primary goal of a covid-19 vaccine is to keep people from getting very sick and dying,” a National Public Radio broadcast said bluntly.6 Peter Hotez, dean of the National School of Tropical Medicine at Baylor College of Medicine in Houston, said, “Ideally, you want an antiviral vaccine to do two things . . . first, reduce the likelihood you will get severely ill and go to the hospital, and two, prevent infection and therefore interrupt disease transmission.”7 Yet the current phase III trials are not actually set up to prove either (table 1). None of the trials currently under way are designed to detect a reduction in any serious outcome such as hospital admissions, use of intensive care, or deaths. Nor are the vaccines being studied to determine whether they can interrupt transmission of the virus. View this table: Table 1 Characteristics of ongoing phase III covid-19 vaccine trials In a September interview Medscape editor in chief Eric Topol pondered what counts as a recorded “event” in the vaccine trials. “We’re not talking about just a PCR [polymerase …

Despite being one of the largest proponents of presently-available COVID-19 vaccines, Gates admits to the failure of the vaccine industry that he has worked tirelessly to prop up.

County also has highest rate of vaccination take-up in the Republic