gov.ie - Claim system open for Multi-Species Sward and Red Clover Silage Measure Applicants
The Department of Agriculture, Food and the Marine has advised that eligible applicant’s participating in the Multi-Species Sward and Red Clover Silage Measures can now up-load their claims for payment
Stomach-affecting intestinal parasites as a precursor model of Pheretima posthuma treated with anthelmintic drug from Dodonaea viscosa Linn.
The preponderance of helminth contagions is constrained to tropical regions and can cause massive vulnerability to malnutrition, anemia, pneumonia, and eosinophilia. Many human parasitic diseases cause severe illness in endemic populations. The helminths transmitting through the gastro-intestinal tract may develop resistance to anthelmintic drugs. The phytotherapy, anthelmintic, and antimicrobial efficacy of Dodonaea viscosa leaf solvent extracts were examined. Phytochemical screening was carried out by ultraviolet (UV) and Fourier transform infrared spectroscopy (FTIR). The anthelmintic activity was performed against a South Indian earth worm as a model by measuring the paralytic time. The antibacterial activity was performed against Bacillus subtilis , Escherichia coli , Klebsiella pneumoniae , and Staphylococcus aureus , which stimulate the stomach helminths. Phytochemical screening revealed the presence of chemical compounds from the UV spectrum, and alkenes and aromatic compounds were confirmed by FTIR. Higher concentrations of the D. viscosa extract showed a rapid paralytic effect with a rapid death rate and histopathology. The zone-of-inhibition study indicated the potent antibacterial activity of the ethanolic and methanolic extracts of D. viscosa against different bacterial species. The current research revealed that D. viscosa has significant anthelmintic and antibacterial activities and it can be used for further elucidation and characterization. Graphical abstract
Compliance with anthelmintic treatment in the neglected tropical diseases control programmes: a systematic review | Parasites & Vectors | Full Text
Preventive chemotherapy (PCT) programmes are used to control five of the highest burden neglected tropical diseases (NTDs): soil-transmitted helminth infections (hookworm, ascariasis, and trichuriasis), lymphatic filariasis, schistosomiasis, onchocerciasis, and trachoma. Over the past decade, new resource commitments for the NTDs have enabled such programmes to intensify their control efforts, and for some diseases, to shift from goals of morbidity control to the interruption of transmission and elimination. To successfully eliminate the parasite reservoir, these programmes will undoubtedly require prolonged, high treatment coverage. However, it is important to consider that even when coverage levels reach an acceptable proportion of the target population, there may be a considerable gap between coverage (those who receive the drug) and compliance (those who actually consume the drug)—a topic of fundamental and perhaps underestimated importance. We conducted a systematic review of published literature that investigated compliance to PCT programmes for NTD control and elimination. Databases searched included PubMed/Medline, Web of Knowledge (including Web of Science), OVID, and Scopus. Data were collected on compliance rates, reasons for non-compliance, as well as the heterogeneity of compliance definitions and calculations across programmes and studies. A total of 112 studies were selected for inclusion. The findings of the review revealed substantial heterogeneity across compliance terms and definitions; an imbalance of available studies for particular disease areas and countries; and finally, a lack of longitudinal compliance studies to properly investigate the role of systematic non-compliance. The lack of consistency among reporting of compliance data can result in under- or over-estimating compliance in a population, and therefore has serious implications for setting and reaching elimination targets. Reframing of the guidelines on compliance definitions coupled with an urgent call for longitudinal research in systematic non-compliance should be essential elements in the programmatic shift from control to elimination.
Compliance with anthelmintic treatment in the neglected tropical diseases control programmes: a systematic review | Parasites & Vectors | Full Text
Preventive chemotherapy (PCT) programmes are used to control five of the highest burden neglected tropical diseases (NTDs): soil-transmitted helminth infections (hookworm, ascariasis, and trichuriasis), lymphatic filariasis, schistosomiasis, onchocerciasis, and trachoma. Over the past decade, new resource commitments for the NTDs have enabled such programmes to intensify their control efforts, and for some diseases, to shift from goals of morbidity control to the interruption of transmission and elimination. To successfully eliminate the parasite reservoir, these programmes will undoubtedly require prolonged, high treatment coverage. However, it is important to consider that even when coverage levels reach an acceptable proportion of the target population, there may be a considerable gap between coverage (those who receive the drug) and compliance (those who actually consume the drug)—a topic of fundamental and perhaps underestimated importance. We conducted a systematic review of published literature that investigated compliance to PCT programmes for NTD control and elimination. Databases searched included PubMed/Medline, Web of Knowledge (including Web of Science), OVID, and Scopus. Data were collected on compliance rates, reasons for non-compliance, as well as the heterogeneity of compliance definitions and calculations across programmes and studies. A total of 112 studies were selected for inclusion. The findings of the review revealed substantial heterogeneity across compliance terms and definitions; an imbalance of available studies for particular disease areas and countries; and finally, a lack of longitudinal compliance studies to properly investigate the role of systematic non-compliance. The lack of consistency among reporting of compliance data can result in under- or over-estimating compliance in a population, and therefore has serious implications for setting and reaching elimination targets. Reframing of the guidelines on compliance definitions coupled with an urgent call for longitudinal research in systematic non-compliance should be essential elements in the programmatic shift from control to elimination.
Med barna i fokus - besteforeldre for en ansvarlig klimapolitikkbesteforeldre for en ansvarlig klimapolitikk
BKA var eneste organisasjon som fokuserte på barnas klima under Arendalsuka, forteller Bente Bakke fra Mysen. Selv sto hun på stand og delte ut materiell hele uka, sammen med deltakere fra flere steder i landet. - Noen av oss gikk også rundt i bygatene med hatter og plakatvester, og ble heiet på av
With the children in focus - grandparents for a responsible climate policygrandparents for a responsible climate policy
BKA var eneste organisasjon som fokuserte på barnas klima under Arendalsuka, forteller Bente Bakke fra Mysen. Selv sto hun på stand og delte ut materiell hele uka, sammen med deltakere fra flere steder i landet. - Noen av oss gikk også rundt i bygatene med hatter og plakatvester, og ble heiet på av
Lagos -- Morrow Batteries (Morrow) and Siva are building a battery factory that will contribute to value creation far beyond the battery coast of southern
It is very important for scientists all over the globe to enhance drug discovery research for better human health. This book demonstrates that various expertise are essential for drug discovery including synthetic or natural drugs, clinical pharmacology, receptor identification, drug metabolism, pharmacodynamic and pharmacokinetic research. The following 5 sections cover diverse chapter topics in drug discovery: Natural Products as Sources of Leading Molecules in Drug Discovery; Oncology and Drug Discovery; Receptors Involvement in Drug Discovery; Management and Development of Drugs against Infectious Diseases; Advanced Methodology.
Pattern of complications and burden of disease in patients affected by beta thalassemia major
A free platform for explaining your research in plain language, and managing how you communicate around it – so you can understand how best to increase its impact.
EJP RD’s ERN Workshops: “Modelling & Simulation: Research Methodologies for Small Populations in Rare Diseases” - Fondation Maladies Rares
In the context of EJP RD’s ERN Workshops, a face-to-face workshop entitled “Modelling & Simulation: Research Methodologies for Small Populations in Rare
G Bonifazi, F Cauteruccio, E Corradini, M Marchetti, G Terracina, D Ursino, L Virgili…, Atti del Trentunesimo Convegno Nazionale su Sistemi Evoluti per Basi di Dati …, 2023
Smart carpet using differential piezoresistive pressure sensors for elderly fall detection | Semantic Scholar
A simple smart carpet design is developed to detect falls using a novel sensing technique that employs differential piezoresistive pressure sensors and can be also integrated in beds to alert patients from falling during sleep. Falls are events that affect almost every aging human being above the age of 65. These incidents can have major consequences on the physiological, psychological and socio-economical levels. In this paper, a simple smart carpet design is developed to detect falls using a novel sensing technique. Conventional sensing methods use either inertial measurement sensors (accelerometers, gyroscopes) or environmental sensors (infrared, force, vibration, acoustic, etc.). The proposed technique employs differential piezoresistive pressure sensors. The prototype of the system is implemented and tested using statistical methods. Experimental results show the sensitivity and the specificity of the system to be 88.8% and 94.9% respectively. The system could be deployed in home care environment as a final product. Our proposed sensing technique can be also integrated in beds to alert patients from falling during sleep.
