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For the past decade, the number of molecular targets for approved drugs has been debated. Here, we reconcile apparently contradictory previous reports into a comprehensive survey, and propose a consensus number of current drug targets for all classes of approved therapeutic drugs. One striking featu …

The increasing use of azole antifungals for the treatment of mucosal and systemic Candida glabrata infections has resulted in the selection and/or emergence of resistant strains. The main mechanisms of azole resistance include alterations in the C. glabrata ERG11 gene (CgERG11), which encodes the az …

Announcing Hazelcast Striim Hot Cache. Reduce the latency of propagation of data from a backend database into a Hazelcast cache to milliseconds.

Mitoxantrone (Novantrone®) is an anthracenedione agent used in the treatment of several types of cancer.

SCHAUMBURG, Ill. — Generic drug maker Sagent Pharmaceuticals has appointed James Hussey as its president, the company said. Sagent said the board of directors' appointment of Hussey, 53, would be effective Monday. Hussey will be responsible for the company's commercial operations, including development, regulatory affairs, supply chain activities, sales, marketing and human resources.

NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine.

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Origene. A GENE CENTRIC LIFE SCIENCE TOOLS COMPANY   OriGene Technologies was founded as a research tool company focused on the creation of the largest commercial collection...

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AbstractBACKGROUND. After spinal cord injury (SCI), most men cannot ejaculate without medical assistance. A major advance in the knowledge of the spinal control