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Lonza is pleased to announce the availability of cryopreserved Clonetics® Human Retinal Pigment Epithelial (hRPE) Cells and optimized RtEGM™ Growth Medium BulletKit® for ophthalmologic research including age-related macular degeneration, retinistis pigmentosa, and gene expression profiles of RPE.

Europe PMC is an archive of life sciences journal literature.

Europe PMC is an archive of life sciences journal literature.

Creating fully human monoclonal antibodies that target and neutralize HIV and other infectious diseases.

Creating fully human monoclonal antibodies that target and neutralize HIV and other infectious diseases.

German automotive association VDA on Wednesday said car sales in January rose 17 percent compared with the year-earlier period, driven by strong domestic demand and increasing appetite for diesel vehicles.

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High quality example sentences with “purchased from Clonetics basel switzerland” in context from reliable sources - Ludwig is the linguistic search engine that helps you to write better in English

A portable data recording system that works on the basis of a microcomputer has been developed. The main advantage of this system consists in the carrying out of checks for illogical and contradictory entries during the process of recording. False entries can immediately be corrected. The data are t …

The nervonic acid levels in the CSF did not differ among the patients with MDD, BD, and the healthy controls; however, a significant negative correlation with depressive symptoms and a positive correlation with manic symptoms was observed. Thus, the nervonic acid levels in the CSF may be a candidate …

German automotive association VDA on Wednesday said car sales in January rose 17 percent compared with the year-earlier period, driven by strong domestic demand and increasing appetite for diesel vehicles.

Dynamic contrast-enhanced MRI is a dynamic imaging technique that is now widely used for cancer imaging. Changes in tumour microvasculature are typically quantified by pharmacokinetic modelling of the contrast uptake curves. Reliable pharmacokinetic parameter estimation depends on the measurement of the arterial input function, which can be obtained from arterial blood sampling, or extracted from the image data directly. However, arterial blood sampling poses additional risks to the patient, and extracting the input function from MR intensities is not reliable. In this work, we propose to compute a perfusion CT based arterial input function, which is then employed for dynamic contrast enhanced MRI pharmacokinetic parameter estimation. Here, parameter estimation is performed simultaneously with intra-sequence motion correction by using nonlinear image registration. Ktrans maps obtained with this approach were compared with those obtained using a population averaged arterial input function, i.e. Orton. The dataset comprised 5 rectal cancer patients, who had been imaged with both perfusion CT and dynamic contrast enhanced MRI, before and after the administration of a radiosensitising drug. Ktrans distributions pre and post therapy were computed using both the perfusion CT and the Orton arterial input function. Perfusion CT derived arterial input functions can be used for pharmacokinetic modelling of dynamic contrast enhanced MRI data, when perfusion CT images of the same patients are available. Compared to the Orton model, perfusion CT functions have the potential to give a more accurate separation between responders and non-responders.

Cultured human keratinocytes provide a model to study a number of medically relevant topics such as metabolism, nutrition, toxicity, differentiation, various epidermal diseases, and the treatment of serious burns.

Cultured human keratinocytes provide a model to study a number of medically relevant topics such as metabolism, nutrition, toxicity, differentiation, various epidermal diseases, and the treatment of serious burns.

Concern that lineup administrators can influence eyewitness identifications has led researchers to suggest implementing double-blind testing, an idea that police resist. Using a typical eyewitness paradigm (video event followed by photographic identification test), the present study demonstrated tha …