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Are stents better for blocked arteries than medications and a healthy lifestyle? Angina, stroke and other vascular conditions are often caused by atherosclerosis ('arteriosclerosis') and treated by stenting, where doctors open up a blocked artery in the heart by inserting a sliver of metal into the artery to keep it open. However, there are allegations that far too many stents are being put in when medications and lifestyle changes could do the job just as well if not better. Norman Swan speaks to leading cardiologist Associate Professor David Playford about treating the person rather than the artery. From the Tonic series produced with the assistance of NPS MedicineWise. Asking the right questions enables you to get the most out of medicines and make better informed decisions about them. Find out what you should know about your medicines and the questions to ask at http://www.nps.org.au/topics/how-to-be-medicinewise/making-wise-choices-about-medicines/questions-to-ask-your-doctor

Scientific teaching requires scientifically constructed, field-tested instruments to accurately evaluate student thinking and gauge teacher effectiveness. We have developed a 23-question, multiple select-format assessment of student understanding of the essential concepts of the central dogma of mol …

Researchers have developed a type of 'smart stent' that monitors even subtle changes in the flow of blood through the artery, detecting the narrowing in its earliest stages and making early diagnosis and treatment possible.

Researchers have developed a type of 'smart stent' that monitors even subtle changes in the flow of blood through the artery, detecting the narrowing in its earliest stages and making early diagnosis and treatment possible.

Brain stents, which are placed to open up a blocked artery and are designed to prevent strokes in high-risk individuals, actually increase the risk of stroke and death considerably, researchers...

Mental techniques, similar to surgical implants, that are used in therapy and are based on the brain's suggestibility and plasticity.

As radiology departments become filmless, they are discovering that some areas are particularly difficult to deliver images. Many departments have found that the operating room is one such area. There are space constraints and difficulty in manipulating the images by a sterile surgeon. This report d …

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Mental techniques, similar to surgical implants, that are used in therapy and are based on the brain's suggestibility and plasticity.

Scientific teaching requires scientifically constructed, field-tested instruments to accurately evaluate student thinking and gauge teacher effectiveness. We have developed a 23-question, multiple select-format assessment of student understanding of the essential concepts of the central dogma of mol …

Molecular docking is central to rational drug design. Current docking techniques suffer, however, from limitations in protein flexibility and solvation models and by the use of simplified scoring functions. All-atom molecular dynamics simulations, on the other hand, feature a realistic representation of protein flexibility and solvent, but require knowledge of the binding site. Recently we showed that coarse-grained molecular dynamics simulations, based on the most recent version of the Martini force field, can be used to predict protein/ligand binding sites and pathways, without requiring any a priori information, and offer a level of accuracy approaching all-atom simulations. Given the excellent computational efficiency of Martini, this opens the way to high-throughput drug screening based on dynamic docking pipelines. In this opinion article, we sketch the roadmap to achieve this goal.

Molecular docking is central to rational drug design. Current docking techniques suffer, however, from limitations in protein flexibility and solvation models and by the use of simplified scoring functions. All-atom molecular dynamics simulations, on the other hand, feature a realistic representation of protein flexibility and solvent, but require knowledge of the binding site. Recently we showed that coarse-grained molecular dynamics simulations, based on the most recent version of the Martini force field, can be used to predict protein/ligand binding sites and pathways, without requiring any a priori information, and offer a level of accuracy approaching all-atom simulations. Given the excellent computational efficiency of Martini, this opens the way to high-throughput drug screening based on dynamic docking pipelines. In this opinion article, we sketch the roadmap to achieve this goal.

Brain stents, which are placed to open up a blocked artery and are designed to prevent strokes in high-risk individuals, actually increase the risk of stroke and death considerably, researchers...

Concept inventories (CIs) are valuable tools for educators that assess student achievement and identify misconceptions held by students. Results of student responses can be used to adjust or develop new instructional methods for a given topic. The regulation of gene expression in both prokaryotes an …

Trying to change a variable name of an XDF with rxSetVarInfo. I want to merge several data sets with common var names. (I know rxMerge can/will append to filenames where needed. I want to have m...

Brain stents, which are placed to open up a blocked artery and are designed to prevent strokes in high-risk individuals, actually increase the risk of stroke and death considerably, researchers...

Absorbable stents, a new angioplasty technology undergoing testing, may lead to fewer repeat procedures to keep arteries clear.

Trying to change a variable name of an XDF with rxSetVarInfo. I want to merge several data sets with common var names. (I know rxMerge can/will append to filenames where needed. I want to have m...