Pilot Programs in Medical Research

A new study by Duke University researchers shows that electrical stimulation of the vagus nerve can reduce the inflammation improve the cognitive outcomes of patients after surgery.

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A device developed by a collaborative team of researchers could turn PET imaging on its head.

A paper-and-string whirligig that costs 20 cents to make could change the game and help end malaria and other worldwide epidemics.

Researchers at UCLA have developed a “nanoblade” that can cut and slice cells, taking the precision of biological research to a level few considered possible.

New biosensing contact lenses are designed to detect glucose levels for diabetics and hold thousands of other possibilities.

A cancer research company's "No Cell Left Behind" technology can identify just five cells in a sample of 30 million.

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Engineers, researchers at Northwestern University and Washington University School of Medicine produced the firstbioelectronic medicine—an implantable device that stimulates nerve regeneration.

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Your source for content, tools and resources to support Growth, Innovation and Collaboration in the Augmented and Virtual Reality community.

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Ischemic stroke results from occlusion of a cerebral artery, and it is the leading cause of disability and the fifth leading cause of death in the United States.1 Cerebral artery occlusion results in irreversible death of a component of cerebral tissue, which is referred to as the core infarction. There is an additional component of brain tissue that is ischemic, but viable, which is commonly referred to as the penumbra. The penumbra is at risk of irreversible infarction if timely restoration of blood flow is not achieved, and the preservation of the penumbra by restoration of arterial blood flow is the target of reperfusion therapy in the treatment of ischemic stroke.

Clinical specimens are each inherently unique, limited and non-renewable. As such, small samples such as tissue biopsies are often completely consumed after a limited number of analyses. Here we present a method that enables fast and reproducible conversion ...

Nature Communications - Whether accelerated Arctic warming is favorable for more frequent severe winter weather remains controversial. Here the authors present an observational analysis that links...

Ischemic stroke results from occlusion of a cerebral artery, and it is the leading cause of disability and the fifth leading cause of death in the United States.1 Cerebral artery occlusion results in irreversible death of a component of cerebral tissue, which is referred to as the core infarction. There is an additional component of brain tissue that is ischemic, but viable, which is commonly referred to as the penumbra. The penumbra is at risk of irreversible infarction if timely restoration of blood flow is not achieved, and the preservation of the penumbra by restoration of arterial blood flow is the target of reperfusion therapy in the treatment of ischemic stroke.

This patent search tool allows you not only to search the PCT database of about 2 million International Applications but also the worldwide patent collections. This search facility features: flexible search syntax; automatic word stemming and relevance ranking; as well as graphical results.

Background Early sepsis diagnosis is crucial for the correct management of burn patients, and it clearly influences outcomes. The systemic inflammatory response triggered by burns mimics sepsis presentation and complicates early sepsis diagnosis. Biomarkers were advocated to aid the diagnosis of early sepsis. Serum procalcitonin (PCT) exhibits fair accuracy and good correlation with sepsis severity, being used in diverse clinical settings. However, few studies have evaluated perioperative changes in PCT levels in burn patients. The present study evaluated PCT kinetics during the first days after burn injury and subsequent surgical interventions to assess PCT utility in distinguishing septic from non-septic inflammatory responses. Methods This study was a retrospective observational study of all burn patients admitted to the Coimbra Burns Unit (Portugal) between January 2011 and December 2014 who presented with a total burn surface area ≥ 15% and who underwent subsequent surgery. PCT kinetics were investigated a) during the first five days after burn injury and b) preoperatively during the five days after surgery in three subsets of patients, including those with no preoperative and no postoperative sepsis (NN), no preoperative but postoperative sepsis (NS), and preoperative and postoperative sepsis (SS). A total of 145 patients met the selection criteria and were included in the analysis. Results PCT levels in the first five days after burn injury were significantly higher in patients who developed at least one sepsis episode (n = 85) compared with patients who did not develop sepsis (n = 60). PCT values > 1.00 ng/mL were clearly associated with sepsis. Study participants (n = 145) underwent a total of 283 surgical interventions. Their distribution by preoperative/postoperative sepsis status was 142 (50.2%) in NN; 62 (21.9%) in NS; and 79 (27.9%) in SS. PCT values exhibited a parallel course in the three groups that peaked on the second postoperative day and returned to preoperative levels on the third day or later. The lowest PCT values were found in NN, and the highest values were observed in SS; the NS values were intermediate. Conclusions PCT kinetics coupled with a clinical examination may be helpful for sepsis diagnosis during the first days after burn injury and burn surgery.

Metallurgical and Materials Transactions A - Ballistic impact experiments were conducted on 12.5 mm thick commercial purity titanium and Ti-6 pct Al-4 pct V alloy plates using steel...

The Gallery at Penn College is dedicated to promoting art appreciation through exhibitions of contemporary art and accompanying programs.

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Procalcitonin concentrations are considered as a component of the inflammatory response and as an acute-phase marker, after shock or tissue injury (i.e. burn, trauma, surgery) or infections and sepsis. No data are so far available on the dynamics of procalcitonin ...

Treasurer Josh Frydenberg says a fall in the unemployment rate below five per cent is a further sign...

Tel: 01773 304700 Quote / Testimonial: Eastwood Primary Care Centre sits at the heart of the community and we are proud to be rated outstanding by CQC and for the contribution we make to healthcare…

* Virus drives risk-averse trade in Asia * China GDP misses expectations, but domestic demand impresses * Powell testimony to continue By Tom Westbrook SINGAPORE, July 15 (Reuters) - Spiking coronavirus cases kept the dollar supported in Asia on Thursday and it clawed back a little of a drop which had followed insistence from Federal Reserve chair Jerome Powell that he isn't in a hurry to withdraw policy support. The dollar was up about half a percent on the New Zealand dollar by midday in Tokyo, up about 0.3% on the Australian dollar and British pound and up roughly 0.1% against the euro. Mixed economic data in China - showing a largely expected growth slowdown, but signs of more resilient domestic demand - also did little to improve the mood.