A brain perfusion scan is a type of brain test that shows the amount of blood taken up in certain areas of your brain. This can provide information on how your brain is functioning. There are several different types of brain perfusion scans.
Could procalcitonin (PCT) be a marker of effectiveness of antibiotic treatment (ABT) in pregnant with not severe community-acquired pneumonia (CAP)? | European Respiratory Society
There is no data on changes of PCT on the background of ABT in pregnant with not severe CAP. Aim: to study the role of dynamic of PCT in pregnant with not severe CAP as a marker of effective ABT. Materials: we studied PCT levels in 35 pregnant with CAP which formed the main group (age (Med [25–75%]) 25 [19–30] yrs, gestational age 30 [27–33] wks) and in a control group of 15 healthy pregnant (age 31 [25–37] yrs, gestational age 35 [34–37] wks). Methods: in pregnant with CAP PCT was measured on admission, before starting ABT (PCT-1) and on the 5th day of therapy (PCT-2). We used SMRT-CO scale to estimate the severity of CAP and respiratory rate (RR), body temperature (BT) and leukocyte count – to monitor clinical status. Results: on admission all patients had high BT (37,9 [37–38,2]°C ), increased RR (28 [24–31] per min.) and leukocytosis (11,9 [8,3–14,3]*109/l), also they had 2 or less points on the SMRT-CO scale which corresponds to not severe CAP. They were prescribed standard ABT with amoxicillin/clavulonate. On the 5th day of ABT we observed a significant decrease of BT, RR and leukocyte count. Dynamics of PCT is shown in [Table 1][1]. View this table: Table 1 Changes of PCT on the background of ABT Conclusion: dynamics of PCT can be used as a marker of effectiveness of ABT in pregnant with not severe CAP. [1]: #T1
Recombinant human granulocyte colony-stimulating factor (filgrastim) following high-dose chemotherapy and peripheral blood progenitor cell rescue in high-grade non-Hodgkin's lymphoma: clinical benefits at no extra cost - PubMed
In order to evaluate the potential clinical and economic benefits of granulocyte colony-stimulating factor (G-CSF, filgrastim) following peripheral blood progenitor cells (PBPC) rescue after high-dose chemotherapy (HDCT), 23 consecutive patients aged less than 60 years with poor-prognosis, high-grad …
An important issue in the health care sector is the collection of information about adverse incidents relative to medical devices and the exchange of this information among Health Care Institutions, Manufacturers and Competent Authorities. We present an Electronic Post Market Surveillance System, wh …
Peripheral blood progenitor cells (PBPCs) have become increasingly popular over the last 15 years as the source of hematopoietic stem cells for transplantation. In the early 1990s, PBPCs replaced bone marrow (BM) as the preferred source of autologous stem cells, and recently the same phenomenon is s …
Stem and progenitor cells: the premature desertion of rigorous definitions: Trends in Neurosciences
A current disturbing trend in stem cell biology is the abandonment of rigorous definitions of stem and progenitor cells in favor of more ambiguous, all-encompassing concepts. However, recent studies suggest that there are consistent, functional differences in the biology of these two cell types. Admittedly, it can be difficult to harmonize the in vivo and in vitro functional differences between stem and progenitor cells. Nonetheless, these distinctions between cell types should be emphasized rather than ignored, as they can be used to test specific hypotheses in neural stem cell biology.
Rational Selection of Bio-Enabling Oral Drug Formulations - A PEARRL Commentary - PubMed
New drug candidates often require bio-enabling formation technologies such as lipid-based formulations, solid dispersions, or nanosized drug formulations. Development of such more sophisticated delivery systems generally requires higher resource investment compared to a conventional oral dosage form …
Local environmental factors determine hematopoietic differentiation of neural stem cells - PubMed
Stem cells exhibit unique properties and hold high therapeutic promise, but factors influencing their differentiation after transplantation need to be recognized and defined for this promise to be fully met. Here, we demonstrate that endogenous colony-forming unit spleen (CFU-S) colonies are not gen …
These results indicate that transplantation of spheroid-loaded tsADMs significantly improved cell delivery. These findings suggest that a combined approach with other cells, drugs, and nanoparticles may improve cell delivery and therapeutic efficacy.
Nervonic acid level in cerebrospinal fluid is a candidate biomarker for depressive and manic symptoms: A pilot study - PubMed
The nervonic acid levels in the CSF did not differ among the patients with MDD, BD, and the healthy controls; however, a significant negative correlation with depressive symptoms and a positive correlation with manic symptoms was observed. Thus, the nervonic acid levels in the CSF may be a candidate …
Strategies to enhance efficacy of SPION-labeled stem cell homing by magnetic attraction: a systemic review with meta-analysis - PubMed
Stem cells possess a promising potential in the clinical field. The application and effective delivery of stem cells to the desired target organ or site of injury plays an important role. This review describes strategies on understanding the effective delivery of stem cells labeled with superparamag …
Low‐dose dynamic myocardial perfusion CT imaging using a motion adaptive sparsity prior - Bian - 2017 - Medical Physics - Wiley Online Library
Medical Physics is an international journal publishing original, high impact physics, imaging science, and engineering research that advances patient diagnosis and therapy.
Physical models can provide superior learning opportunities beyond the benefits of active engagements - PubMed
The essence of molecular biology education lies in understanding of gene expression, with subtopics including the central dogma processes, such as transcription and translation. While these concepts are core to the discipline, they are also notoriously difficult for students to learn, probably becau …
IU - A Digital Application for the Graphical Examination of Interpersonal Attachment - PubMed
Human attachment describes the establishment of contact between two or more people leading to a closer interpersonal relationship. For measuring attachment, the use of nonverbal assessments tools including art and drawing tasks has been shown to be an alternative to conventional assessment approache …
Too much of a good thing? Curvilinear relationships between self-calming and autonomic responses in paediatric patients - PubMed
Based on the theory of self-regulation and the polyvagal theory, we hypothesise a curvilinear relationship between self-regulation and autonomic responses. We report findings of a pilot study that provides support for the proposed hypothesis. For some of the observed cases, the quadratic polynomial …
Piloting a Mindfulness-Based Intervention to Veterinary Students: Learning and Recommendations - PubMed
Veterinary students experience high levels of psychological distress including anxiety, stress, perceived stress and depression. The inability to cope with the demands of veterinary training has personal and professional consequences. Existing evidence shows that mindfulness-based interventions (MBI …
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