Procalcitonin (PCT) ELISA, BE69219 (RUO) | IBL America
Enzyme-linked immune-sorbent assay (ELISA) for the determination of PCT in human serum, plasma, tissue homogenates or cell culture supernatants. For research use only, not for use in diagnostic procedures.
Intellectual property in India is a subordinate office of the Govt of India & administers the Indian law for Patents, Designs, Trade Marks & Geographical Indica
Computerised Methodologies for Non-Invasive Angiography-Derived Fractional Flow Reserve Assessment: A Critical Review
Fractional flow reserve is the gold standard for assessing the haemodynamic significance of intermediate coronary artery stenoses. Cumulative evidence has shown that FFR-guided revascularisation reduces stent implantations and improves patient outcomes. However, despite the wealth of evidence and guideline recommendations, its use in clinical practice remains minimal. Patient and technical limitations of FFR as well as the need for intracoronary instrumentation, use of adenosine, and increased costs have limited FFR’s applicability in clinical practice. Over the last decade, several angiography-derived FFR software packages have been developed which do not require intracoronary pressure assessment with a guidewire or need for administration of hyperaemic agents. At present, there are 3 commercially available software packages and several other non-commercial technologies that have been described in the literature. These technologies have been validated against invasive FFR showing good accuracy and correlation. However, the methodology behind these solutions is different—some algorithms are based on solving the governing equations of fluid dynamics such as the Navier–Stokes equation while others have opted for a more simplified mathematical formula approach. The aim of this review is to critically appraise the methodology behind all the known angiography-derived FFR technologies highlighting the key differences and limitations.
Noninvasive Fractional Flow Reserve and the Heart Team Decision Process | Circulation: Cardiovascular Interventions
Correspondence to: Julinda Mehilli, MD, Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Ludwig-Maximilians-Universität, Marchioninistr. 15, Munich 81377. Email
Simplified Models of Non-Invasive Fractional Flow Reserve Based on CT Images
Invasive fractional flow reserve (FFR) is the gold standard to assess the functional coronary stenosis. The non-invasive assessment of diameter stenosis (DS) using coronary computed tomography angiography (CTA) has high false positive rate in contrast to FFR. Combining CTA with computational fluid dynamics (CFD), recent studies have shown promising predictions of FFRCT for superior assessment of lesion severity over CTA alone. The CFD models tend to be computationally expensive, however, and require several hours for completing analysis. Here, we introduce simplified models to predict noninvasive FFR at substantially less computational time. In this retrospective pilot study, 21 patients received coronary CTA. Subsequently a total of 32 vessels underwent invasive FFR measurement. For each vessel, FFR based on steady-state and analytical models (FFRSS and FFRAM, respectively) were calculated non-invasively based on CTA and compared with FFR. The accuracy, sensitivity, specificity, positive predictive value and negative predictive value were 90.6% (87.5%), 80.0% (80.0%), 95.5% (90.9%), 88.9% (80.0%) and 91.3% (90.9%) respectively for FFRSS (and FFRAM) on a per-vessel basis, and were 75.0%, 50.0%, 86.4%, 62.5% and 79.2% respectively for DS. The area under the receiver operating characteristic curve (AUC) was 0.963, 0.954 and 0.741 for FFRSS, FFRAM and DS respectively, on a per-patient level. The results suggest that the CTA-derived FFRSS performed well in contrast to invasive FFR and they had better diagnostic performance than DS from CTA in the identification of functionally significant lesions. In contrast to FFRCT, FFRSS requires much less computational time.
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Industrial Minerals and Rocks: (nonmetallics Other Than Fuels) - American Institute of Mining, Metallurgical, and Petroleum Engineers, American Institute of Mining, Metallurgical, and Petroleum Engineers. Committee on the Industrial Minerals Volume - Google Books
* Virus drives risk-averse trade in Asia * China GDP misses expectations, but domestic demand impresses * Powell testimony to continue By Tom Westbrook SINGAPORE, July 15 (Reuters) - Spiking coronavirus cases kept the dollar supported in Asia on Thursday and it clawed back a little of a drop which had followed insistence from Federal Reserve chair Jerome Powell that he isn't in a hurry to withdraw policy support. The dollar was up about half a percent on the New Zealand dollar by midday in Tokyo, up about 0.3% on the Australian dollar and British pound and up roughly 0.1% against the euro. Mixed economic data in China - showing a largely expected growth slowdown, but signs of more resilient domestic demand - also did little to improve the mood.
Valerie P. Jackson, MD, was named president of the Radiological Society of North America (RSNA) Board of Directors, Wednesday, Nov. 28, at its annual meeting in Chicago.
