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Planning virtual residency interviews as a result of COVID-19: insight from residency applicants and physicians conducting interviews | Postgraduate Medical Journal
Planning virtual residency interviews as a result of COVID-19: insight from residency applicants and physicians conducting interviews | Postgraduate Medical Journal
Background In response to the COVID-19 pandemic, the 2020–2021 residency interview process will undergo significant changes. Residency programme stakeholders would benefit from knowledge on what students and physicians expect from this process. Objective The purpose of the study was to describe and contrast the perspectives of student applicants and interviewing physicians related to the residency programme virtual interview process. Methods A survey consisting of 24 Likert statements was administered across listservs in summer 2020 to physicians (attendings and residents who interview medical students). Medical students also received an anonymous survey and were recruited via email to participate. Results A total of 155 individuals (104 fourth-year medical students and 51 physicians) completed a survey. Results showed students would prefer in-person interviews over virtual. Residency applicants had high agreement on the limited ability to fully assess the programme and city due to virtual interviews. Individuals with lower step 1 scores had higher agreement on preferring in-person interviews. Individuals in the lowest and highest scoring groups appear more worried about the representation of themselves as a result of virtual interviews. Furthermore, applicants feel that more weight will be placed on steps 1 and 2 scores and class ranks, and they may not be able to fully demonstrate their personality compared with interviewers. Conclusion The result of COVID-19 has created challenges and subsequent reshuffling of medical education requiring careful preparation and planning. This study provides insight for residency programmes to better understand the applicants’ expectations for the 2020–2021 residency interview and matching process. No data are available.
·pmj.bmj.com·
Planning virtual residency interviews as a result of COVID-19: insight from residency applicants and physicians conducting interviews | Postgraduate Medical Journal
Leveraging Virtual Residency Applications to Advantage All - Neurology Blogs
Leveraging Virtual Residency Applications to Advantage All - Neurology Blogs
Commentary on: Maximizing Inclusiveness and Diversity through Virtual Residency Applications and Interviews by Budhu et al As medical students and residency programs enter the second year of virtual recruitment and interviews, much has been learned but much still needs to be addressed. In the recent Resident and Fellow Section of Neurology article by Budhu et...
·blogs.neurology.org·
Leveraging Virtual Residency Applications to Advantage All - Neurology Blogs
Planning virtual residency interviews as a result of COVID-19: insight from residency applicants and physicians conducting interviews | Postgraduate Medical Journal
Planning virtual residency interviews as a result of COVID-19: insight from residency applicants and physicians conducting interviews | Postgraduate Medical Journal
Background In response to the COVID-19 pandemic, the 2020–2021 residency interview process will undergo significant changes. Residency programme stakeholders would benefit from knowledge on what students and physicians expect from this process. Objective The purpose of the study was to describe and contrast the perspectives of student applicants and interviewing physicians related to the residency programme virtual interview process. Methods A survey consisting of 24 Likert statements was administered across listservs in summer 2020 to physicians (attendings and residents who interview medical students). Medical students also received an anonymous survey and were recruited via email to participate. Results A total of 155 individuals (104 fourth-year medical students and 51 physicians) completed a survey. Results showed students would prefer in-person interviews over virtual. Residency applicants had high agreement on the limited ability to fully assess the programme and city due to virtual interviews. Individuals with lower step 1 scores had higher agreement on preferring in-person interviews. Individuals in the lowest and highest scoring groups appear more worried about the representation of themselves as a result of virtual interviews. Furthermore, applicants feel that more weight will be placed on steps 1 and 2 scores and class ranks, and they may not be able to fully demonstrate their personality compared with interviewers. Conclusion The result of COVID-19 has created challenges and subsequent reshuffling of medical education requiring careful preparation and planning. This study provides insight for residency programmes to better understand the applicants’ expectations for the 2020–2021 residency interview and matching process. No data are available.
·pmj.bmj.com·
Planning virtual residency interviews as a result of COVID-19: insight from residency applicants and physicians conducting interviews | Postgraduate Medical Journal
EMRA Virtual Residency Program Fair EMRA
EMRA Virtual Residency Program Fair EMRA
EMRA is offering our Virtual Residency Program Fair at NO COST to EMRA medical student members. To take care of our members preparing for Match, MSIVs will have first access. As space allows, we will open registration to all medical student members.
·emra.org·
EMRA Virtual Residency Program Fair EMRA
Metastatic castration-sensitive prostate cancer: Abiraterone, docetaxel, or… - PubMed
Metastatic castration-sensitive prostate cancer: Abiraterone, docetaxel, or… - PubMed
For decades, the management of patients with advanced prostate cancer has been hormonal therapy, known as androgen deprivation therapy, which is intended to lower testosterone levels. Further incremental progress in the treatment of men with metastatic hormone-sensitive prostate cancer (mHSPC) has c …
·pubmed.ncbi.nlm.nih.gov·
Metastatic castration-sensitive prostate cancer: Abiraterone, docetaxel, or… - PubMed
Using CAR T Cell Therapy to Target Metastatic Castration-Resistant Prostate Cancer in a Phase 1 Trial
Using CAR T Cell Therapy to Target Metastatic Castration-Resistant Prostate Cancer in a Phase 1 Trial
Associate professor of medicine in the Department of Medical Oncology & Therapeutics Research, Tanya Dorff, M.D., is leading a Phase 1 clinical trial that is studying chimeric antigen receptor (CAR) T cells with specificity to prostate stem cell antigen positive (PSCA+) mCRPC.
·cityofhope.org·
Using CAR T Cell Therapy to Target Metastatic Castration-Resistant Prostate Cancer in a Phase 1 Trial
Frontiers | Prostate Cancer Stem Cells and Nanotechnology: A Focus on Wnt Signaling
Frontiers | Prostate Cancer Stem Cells and Nanotechnology: A Focus on Wnt Signaling
Prostate cancer is the most common cancer among men worldwide. However, current treatments for prostate cancer patients in advanced stage often fail because of relapse. Prostate cancer stem cells (PCSCs) are resistant to most standard therapies, and are considered to be a major mechanism of cancer metastasis and recurrence. In this review, we summarized current understanding of PCSCs and their self-renewal signaling pathways with a specific focus on Wnt signaling. Although multiple Wnt inhibitors have been developed to target PCSCs, their application is still limited by inefficient delivery and toxicity in vivo. Recently, nanotechnology has opened a new avenue for cancer drug delivery, which significantly increases specificity and reduces toxicity. These nanotechnology-based drug delivery methods showed great potential in targeting PCSCs. Here, we summarized current advancement of nanotechnology-based therapeutic strategies for targeting PCSCs and highlighted the challenges and perspectives in designing future therapies to eliminate PCSCs.
·frontiersin.org·
Frontiers | Prostate Cancer Stem Cells and Nanotechnology: A Focus on Wnt Signaling
The Contributions of Prostate Cancer Stem Cells in Prostate Cancer Initiation and Metastasis - PMC
The Contributions of Prostate Cancer Stem Cells in Prostate Cancer Initiation and Metastasis - PMC
Research in the last decade has clearly revealed a critical role of prostate cancer stem cells (PCSCs) in prostate cancer (PC). Prostate stem cells (PSCs) reside in both basal and luminal layers, and are the target cells of oncogenic transformation, suggesting ...
·ncbi.nlm.nih.gov·
The Contributions of Prostate Cancer Stem Cells in Prostate Cancer Initiation and Metastasis - PMC
Targeting prostate cancer stem-like cells by an immunotherapeutic platform based on immunogenic peptide-sensitized dendritic cells-cytokine-induced killer cells | Stem Cell Research & Therapy | Full Text
Targeting prostate cancer stem-like cells by an immunotherapeutic platform based on immunogenic peptide-sensitized dendritic cells-cytokine-induced killer cells | Stem Cell Research & Therapy | Full Text
Background Autologous cellular immunotherapy or immune enhancement therapy has demonstrated some promising benefits for prostate cancer. T cell-based immunotherapy or sipuleucel-T therapy has yielded certain beneficial responses and a slight improvement on the overall survival of patients with metastatic castration-resistant prostate cancer (mCRPC) as shown in some clinical trials, suggesting that prostate cancer is immunoresponsive. Methods In this study, we developed an adaptive cytokine-induced killer cell (CIK)-based immunotherapeutic application targeting the prostate cancer stem-like cells (PCSCs). In this therapeutic platform, dendritic cells (DC) were isolated from the peripheral blood mononuclear cells (PBMCs) and preloaded or sensitized with immunogenic peptides derived from two PCSC-associated cell membrane molecules, CD44 and EpCAM, followed by co-culture with the expanded peripheral blood lymphocyte (PBL)-derived CIK cells. The in vitro cytotoxic activity of DC-activated CIK cells against PCSCs was determined by CCK8 and TUNEL assays, and the in vivo anti-tumor effect of DC-activated CIK cells on prostate cancer xenograft tumors was evaluated in subcutaneous and orthotopic xenograft models. Results Our results showed that the peptide-sensitized DC-CIK cell preparation manifested significant in vitro cytotoxic activity against the PCSC-enriched prostatospheroids and also in vivo anti-tumor effect against prostate cancer xenografts derived from the PCSC-enriched prostatospheroids. Conclusions Together, our established immunogenic peptide-sensitized DC-CIK-based cell preparation platform manifests its potential immunotherapeutic application in targeting the PCSCs and also prostate cancer.
·stemcellres.biomedcentral.com·
Targeting prostate cancer stem-like cells by an immunotherapeutic platform based on immunogenic peptide-sensitized dendritic cells-cytokine-induced killer cells | Stem Cell Research & Therapy | Full Text
Stem Cell Treatment for Prostate Cancer | Stem Cell Mexico
Stem Cell Treatment for Prostate Cancer | Stem Cell Mexico
Stem Cell Cellular Therapy for Prostate Cancer Patients (Immunotherapy) Cellular therapy for prostate cancer patients also known as immunotherapy*, is a natural autologous cellular treatment that employs the use of dendritic cells, natural killer cells (NK cells), and lymphokine-activated killer cells (LAK cells) to suppress
·stemcellmexico.org·
Stem Cell Treatment for Prostate Cancer | Stem Cell Mexico