Descriptive study of the challenges when implementing an app for patients with neovascular age-related macular degeneration to monitor their vision at home - PubMed
CardioMEMS monitoring device migration: A rare complication - PubMed
We present a rare case of CardioMEMS device migration six years post-implantation. Much is still being learned about endothelization of pulmonary vasculature and this case highlights the importance of device surveillance and device-related complications.
Implementation of an epicardial implantable MEMS sensor for continuous and real-time postoperative assessment of left ventricular activity in adult minipigs over a short- and long-term period - PubMed
The sensing of left ventricular (LV) activity is fundamental in the diagnosis and monitoring of cardiovascular health in high-risk patients after cardiac surgery to achieve better short- and long-term outcome. Conventional approaches rely on noninvasive measurements even if, in the latest years, inv …
Millimeter-scale magnetic implants paired with a fully integrated wearable device for wireless biophysical and biochemical sensing - PubMed
Implantable sensors can directly interface with various organs for precise evaluation of health status. However, extracting signals from such sensors mainly requires transcutaneous wires, integrated circuit chips, or cumbersome readout equipment, which increases the risks of infection, reduces bioco …
Digital health care solution for proactive heart failure management with the Cordella Heart Failure System: results of the SIRONA first-in-human study - PubMed
The initial experience of the CHFS incorporating comprehensive vital signs and pulmonary artery pressure monitoring enables safe and accurate monitoring of HF status.
PAR-08-023: Predictive Multiscale Models of the Physiome in Health and Disease (R01)
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Predictive Multiscale Models of the Physiome in Health and Disease (R01) PAR-08-023. NIBIB
NOT-OD-08-118: Announcing Initial Implementation Timeline for Enhancing Peer Review
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Announcing Initial Implementation Timeline for Enhancing Peer Review NOT-OD-08-118. NIH
RFA-EB-09-001: Development and Translation of Medical Technologies that Reduce Health Disparities (SBIR [R43/R44])
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Development and Translation of Medical Technologies that Reduce Health Disparities (SBIR [R43/R44]) RFA-EB-09-001. NIBIB
RFA-DK-09-001: Small Business Innovation Research to Develop New Therapeutics and Monitoring Technologies for Type 1 Diabetes (T1D). Towards an Artificial Pancreas (SBIR) [R43/R44])
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Small Business Innovation Research to Develop New Therapeutics and Monitoring Technologies for Type 1 Diabetes (T1D). Towards an Artificial Pancreas (SBIR) [R43/R44]) RFA-DK-09-001. NIDDK
Eight Stories of Locked-In Syndrome | Mental Floss
Imagine losing control over everything. You can't move on your own. You can't scratch an itch. And worse still, you can't tell anyone around you that you have an itch. You can feel pain, hunger, loneliness, and fear, but you can't react to those sensations. You are totally aware of your surroundings, but you can't communicate your feelings or desires, or even your basic needs. The term for this horror is locked-in syndrome. Someone with locked-in syndrome suffers from paralysis of all voluntary muscles
Survival of Persons With Locked-In Syndrome - Archives of Physical Medicine and Rehabilitation
In a 1987 study, Haig et al1 reported on 27 patients with locked-in syndrome (LIS). A slightly expanded group of 29 patients was studied by Katz2 and Doble3 and colleagues. To our knowledge, these are the largest follow-up studies of persons with LIS, and the only ones to report survival probabilities. Their findings on longevity were summarized by Doble as follows: “Five-, 10-, and 20-year survival were 83%, 83%, and 40% respectively.”3(p438)
Frontiers | Locked-in Syndrome in a Young Patient Due to SARS-CoV-2: A Case Report | Medicine
Coronavirus disease 2019 (COVID-19), apart from commonly involving the respiratory system, has its impact on the central nervous system, with a wide spectrum of clinical presentations ranging from headaches to ischemic strokes. The ongoing research regarding this novel disease has found that there is a very high prevalence of thrombotic episodes especially in critically ill patients when compared to severe presentation of other viral illnesses. This COVID-19-associated coagulopathy has a very complex etiology with the ability to form thrombus in arteries, veins, and microvasculatures of different organs. We present a unique case of a young woman with underlying COVID-19 who unfortunately developed locked-in syndrome due to bilateral pontine infarction during the course of her illness.
Surviving locked-in syndrome: How one man confounded expectations of death - YouTube
Rushed to a Massachusetts emergency room four years ago, 28-year-old Jacob Haendel exhibited signs of stroke. Doctors thought Haendel was in a vegetative state and would soon die, but the one-time chef was very much awake and conscious, suffering from locked-in syndrome – a purgatory between life and death. Correspondent Lee Cowan talks with Haendel about his extraordinarily rare medical trauma, and about his remarkable recovery.
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Locked-in syndrome after brain stem stroke | Stroke Association
A stroke in the brain stem can cause the very rare condition of locked-in syndrome, where the person is conscious but unable to move apart from their eyes.