- From Cytochromes P450 And Exosomes To Hiv Medicine...

Scientific Reports - Multifunctional Nanotherapeutics for the Treatment of neuroAIDS in Drug...

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Neuroscience Research on Drug Abuse (R21) PA-13-337. NIDA

HIV Associated Neurocognitive Disorder (HAND) is one of the most common and clinically important complications of HIV infection. Neurotoxicity is due to the acc...

The latest statistics on the world epidemic of AIDS &HIV report that are at least 40 million people are infected with HIV with nearly 6 million cases of AIDS wo...

In a task oriented domain, recognizing the intention of a speaker is important so that the conversation can proceed in the correct direction. This is possible only if there is a way to label the ut...

HIV associated neurocognitive disorders (HAND) are the spectrum of cognitive impairments present in patients infected with human immunodeficiency virus type 1 (HIV-1). The number of patients affected with HAND ranges from 30 to 50% of HIV infected individuals and although the development of combinational antiretroviral therapy (cART) has improved longevity, HAND continues to pose a significant clinical problem as the current standard of care does not alleviate or prevent HAND symptoms. At present, the pathological mechanisms contributing to HAND remain unclear, but evidence suggests that it stems from neuronal injury due to chronic release of neurotoxins, chemokines, viral proteins, and proinflammatory cytokines secreted by HIV-1 activated microglia, macrophages and astrocytes in the central nervous system (CNS). Furthermore, the blood–brain barrier (BBB) not only serves as a route for HIV-1 entry into the brain but also prevents cART therapy from reaching HIV-1 brain reservoirs, and therefore could play an important role in HAND. The goal of this review is to discuss the current data on the epidemiology, pathology and research models of HAND as well as address the potential pharmacological treatment approaches that are being investigated.

Remember the Gilligan’s Island episode where Gilligan could pick up radio signals from the fillings in his teeth? That is happening all the time. Voice To Skull makes it all possible.  Once t…

Europe PMC is an archive of life sciences journal literature.

The metal-oxide (SiO2)-semiconductor (Si) is the most common microelectronic structures nowadays. The two terminals of MOS-Capacitor consist of the main structures in MOS devices and it is the …

Element is a Matrix-based end-to-end encrypted messenger and secure collaboration app. It’s decentralised for digital sovereign self-hosting, or through a hosting service such as Element Matrix Services. Element operates on the open Matrix network to provide interoperability and easy connections.

Yonhap news articles produced by building a network covering domestic supplies in various newspapers, broadcasting and government departments, major institutions, major corporations, media ,K-pop, K-wave, Hallyu, Korean Wave, Korean pop, Korean pop culture, Korean culture, Korean idol, Korean movies, Internet media and international agreements of the Republic of Korea.

The powder is perfectly lined on the table. With no straw handy, you roll up a Washington and seconds later, the snow is gone. Inhaled into your nostril, it has started a trip that will change your brain...forever.

Audit Risk Assessment: The Why and the How Are you looking for a way to be more efficient and effective in your audits? A proper use of audit risk assessment procedures and the risk of material misstatement formula is your best opportunity. Click here to learn how.

The mental health workforce in the United States is a leader in mental health and substance abuse treatment innovation. Currently, the vast majority of treatment focus is on the relatively small portion of the population that is substance dependent, but those with an “at-risk” level of use may go untreated. Only 5 percent of the...continue reading

CM Furnace makes high throughput production and batch furnaces, lab furnaces, ceramic kilns, box, tube, & muffle furnaces capable of 2200C in multiple atmospheres. USA Made.

Click or tap to learn more.

“People that have been identified as Targeted Individuals are the first waves of humans being secretly experimented upon for testing out this AI surveillance system, by using an assortment of…

Advanced Colloidal Micelles Nano-technology Insecticide and Fungicide uses USP grade oil, plant extracts, and organic acid mixed into colloidal micelles (supramolecular surfactants). These micelles attract large particles using encapsulation. This encapsulation covers, maintains plant surface efficacy long-term, while increasing general plant health and BRIX score. Insect Control - Kills sap-sucking insects on several different levels: dissolves

A police report has been lodged against a Telegram group comprising 40,000 male members, sharing photos and personal details of women, without their consent.