Aggressive use of antiretroviral therapy has led to excellent viral suppression within the systemic circulation. However, despite these advances, HIV …

A novel macromolecular prodrug strategy was developed for the combinatorial delivery of two poorly water-soluble drugs, dexamethasone and doxorubicin.…

Cationic nanohydrogel particles have become an attractive tool for systemic siRNA delivery, but improvement of their in vivo tolerance is desirable, e…

Prevention and early intervention strategies can reduce the impact of substance use and mental disorders in America’s communities.

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Answer (1 of 2): v2k doesnt work on me. im sure they try that with the people it does work on, though. I.m.o.I dont think they have the ability to control what youre actually thinking they just try to brainwash and hypnotize people to commit crimes.or place suggestive subliminal messaging eve...

This is a sub dedicated to the topics of Gangstalking, electronic harassment/torture, Microwave RF, V2K, MK Ultra, evidence of these things and my...

One of the most powerful things about ANSYS Mechanical is the fact that it creates an input file that is sent to ANSYS Mechanical APDL (MAPDL) to solve. This is awesome because you as a user have c…

Interventions for auditory hallucinations in schizophrenia should be coordinated with patients to fit their needs.

What is the Risk Matrix and how can project managers use it for risk assessment in project management? We explore in our latest blog post.

Abstract VOL: 99, ISSUE: 47, PAGE NO: 38 Charlie Place, RMN, is community mental health nurse, South Leeds Intensive Home Treatment Team, Leeds Mental

The National Institute of Mental Health (NIMH) and the Ragon Institute of MGH, MIT, and Harvard conducted a virtual meeting, Macrophage Infection by HIV: Implications for Pathogenesis and Cure, from October 13-14, 2021. This video is Day 2.

The NIMH, National Institute of Neurological Disorders and Stroke, and National Institute on Aging conducted a virtual meeting on the neurologic and psychiatric effects of SARS-CoV-2 infection.

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We posit that improvements in pharmacokinetics and biodistributions of antiretroviral therapies (ART) for human immunodeficiency virus-type one infected people can be achieved through developments in nanoformulations. To this end, we manufactured nanoparticles ...

F-652 is a recombinant fusion protein consisting of two human interleukin-22 (IL-22) molecules linked to an immunoglobulin constant region (IgG[2] -Fc). IL-22 plays critical roles in promoting tissue repair and suppressing bacterial infection. The safety, ...

While PTEN-induced kinase 1 (PINK1) is well characterized for its role in mitochondrial homeostasis, much less is known concerning its ability to prevent synaptodendritic degeneration. Using unbiased proteomic methods, we identified valosin-containing ...

Dysfunctional macrophages underlie the development of several diseases including atherosclerosis where accumulation of cholesteryl esters and persistent inflammation are 2 of the critical macrophage processes that regulate the progression as well as stability ...

Excitatory synapses are specialized cell–cell contacts located on actin-rich dendritic spines that mediate information flow and storage in the brain. The postsynaptic adhesion-G protein-coupled receptor (A-GPCR) BAI1 is a critical regulator of ...

There are few tissue-based biomarkers that can accurately predict prostate cancer (PCa) progression and aggressiveness. We sought to evaluate the clinical utility of prostate and breast overexpressed 1 (PBOV1) as a potential PCa biomarker.Patient tumor ...