Research

Rush University’s Office of Research Affairs has two institutional review boards (IRBs) as part of its human research protections program (HRPP). Each IRB is equally constituted and reviews the same types and levels of research. Each IRB meets once a week, every week throughout the calendar year. All research studies, including those that may qualify for exemption, must be

The Treatment Intervention Advisory Committee (TIAC) was formed early in 2011 to support the Department of Health Services (DHS) in ensuring quality services are available to the citizens of Wisconsin.

The following applications and guidance documents are meant to assist new researchers in completing their IRB applications. PI permission has been obtained and PIs had the option of retaining their names on the application or removing identifying information. These sample applications are meant for training University researchers in completing a Montclair State University IRB application. For […]

Answer (1 of 5): Intervention Review Boards look at grant proposals to make sure that any proposed human subjects intervention has informed consent, is not harmful, and is consistent with a sound methodology. All projects that meet the federal definition of research with human subjects (45 CFR 46...

The Cessation of Smoking Trial in the Emergency Department (COSTED) study demonstrates that a brief intervention including e-cigarette starter kits can significantly help smokers in emergency departments quit, offering a new avenue to tackle smoking rates and associated health inequalities.

A single trial is complex, with numerous regulations, administrative processes, medical procedures, deadlines and specific protocol instructions to follow. And yet, there has existed no single-volume, comprehensive clinical research reference manual for investigators, medical institutions, and national and international research personnel to keep on the shelf as a ready reference to navigate through trial complexities and ensure compliance with U.S. Federal Regulations and ICH GCP until The Sourcebook for Clinical Research. An actionable, step-by-step guide through beginning to advanced topics in clinical research with forms, templates and checklists to download from a companion website, so that study teams will be compliant and will find all the necessary tools within this book. Additionally, the authors developed Display Posters for Adverse Events Plus Reporting and Medicare Coverage Analysis that can be purchased separately here: https://www.elsevier.com/books-and-journals/book-companion/9780128162422/order-display-posters. Moreover, The Sourcebook for Clinical Research contains clear information and guidance on the newest changes in the industry to keep seasoned investigators and staff current and compliant, in addition to providing detailed information regarding the most complex topics. This book serves as a quick, actionable, off-the-shelf resource to keep by your side at the medical clinic. Makes vital trial conduct information easy to understand and instructs on how to practically apply current Federal regulations and Good Clinical Practice (ICH GCP) Offers extensive guidance that is crucial for guaranteeing compliance to clinical research regulations during each step of the clinical research process Provides up-to-date and extensive coverage of beginning to advanced topics, and, step-by-step actions to take during exceptional circumstances, including compassionate use, emergency use, human subjects protections for vulnerable populations, and federal audits Furnishes a detailed clinical research Glossary, and a comprehensive Appendix containing ready-to-use forms, templates, and checklists for clinical trial personnel to download and begin using immediately. Written for the fast-paced clinic environment with action steps and forms in the book to respond to a research subject’s needs urgently and compliantly

Scientific Reports - Effect of CHST11, a novel biomarker, on the biological functionalities of clear cell renal cell carcinoma

Our study confirms that even a lower dose of drugs can induce a clinically useful result. This study confirms that the useful effect of mesotherapy is only partly due to the pharmacological action. Further randomized prospective studies are needed to standardize the technique in the various pain syn …

Intradermal (ID) vaccination can offer improved immunity and simpler logistics of delivery, but its use in medicine is limited by the need for simple, reliable methods of ID delivery. ID injection by the Mantoux technique requires special training and ...

Opens pdf to download Opens document to download Opens in a new window External link will open in a new window.  Click link to exit Virginia Department of Health Website.

Intradermal Injection Because little systemic absorption of intradermally injected agents takes place, this type of injection is used primarily to produce a local effect, as in allergy or tuberculi…

Intradermal injection, often abbreviated ID, is a shallow or superficial injection of a substance into the dermis, which is located between the epidermis and the hypodermis. This route is relatively rare compared to injections into the subcutaneous tissue or muscle. Due to the more complex use, ID injections are not...

Cancer patients are experiencing an increase in overall survival as a consequence of earlier diagnosis and newer effective anticancer therapies. However, cancer survivors often face long-term consequences from their original cancer diagnosis and long-term ...

While rare, complications do occur with the esthetic use of dermal fillers. Careful attention to patient factors and technique can do much to avoid these complications, and a well-informed practitioner can mitigate problems when they do occur. Since cosmetic ...

Procedural sedation may be needed in many diagnostic and therapeutic procedures in children. To make pediatric procedural sedation as safe as possible, protocols should be developed by institutions. Response to sedation in children is highly variable, ...

"Another step toward a dystopian future unimaginable just five years ago..."