Based on the article, the main threats mentioned include:
Escalation of conflict between Iran and Israel into a wider regional or global war
Formation of an "Axis of Upheaval" by Iran, China, and Russia to challenge American dominance
Middle East potentially becoming a superpower battlefield
Russia's advances in Ukraine and destabilizing influence in Africa
China's imperial ambitions over Taiwan and the South China Sea
Rise of authoritarian models challenging the liberal world order
Europe's industrial decline and economic vulnerability
Potential fragmentation of Europe under pressure from the East
Energy security concerns for Europe
Iran-Russia-China militarism
Dismantling of the liberal world order that has driven social, technological, and economic progress
China's exploitative practices in Africa, including labor abuse and predatory lending
Russia's neo-imperialism in Africa
Threat to globalization and its associated benefits of liberalism, freedom, democracy, and prosperity