****!!!!****!!!!**** "Decontamination of Category A Viruses on Porous Surfaces and Sensitive Equipment: ...The prototype will ultimately be evaluated in accordance with an EPA-approved protocol entitled “Efficacy of a Disinfectant Applied to a Room Via a Fogger or Misting Device” against a panel of organisms. The results will be submitted to the EPA to register the technology as a room disinfection device and claim “hospital and broad-spectrum” and “virucide” efficacy." "METSS is currently conducting a Phase II SBIR project for the EPA to develop a safe, robust, rapid, and effective chlorine dioxide (ClO2) gas dispersion system to be used for on-site room decontamination in hospital and non-hospital settings. This technology will meet the demands of the health care market to decontaminate porous materials and sensitive equipment in rooms or vehicles used for patient care or transport. This need was evident during the care and treatment of Ebola patients in the United States several years ago. At that time, it was clear that many facilities did not have the means to properly disinfect large items, like furniture, on-site; therefore, the items required transport off-site for proper treatment and disposal; a process that has inherent safety risks and associated costs. The ability to decontaminate a room containing porous materials and sensitive equipment on-site and in a non-destructive manner would be invaluable to the health care industry and meet a critical need for low-cost, simple solutions to decontaminate non-medical spaces as well. Based on feedback from potential end-users and results of development testing conducted during the first year of the project, a functional prototype is currently being designed, constructed, and tested. The prototype will ultimately be evaluated in accordance with an EPA-approved protocol entitled “Efficacy of a Disinfectant Applied to a Room Via a Fogger or Misting Device” against a panel of organisms. The results will be submitted to the EPA to register the technology as a room disinfection device and claim “hospital and broad-spectrum” and “virucide” efficacy."

"There are three main preventive measures for airborne infectious diseases, one is to find and eliminate the source of infectious diseases; The second is to use vaccines or increase immunity to resist the invasion of infectious diseases; The third is to block or eliminate the transmission route of infectious diseases. Since severe acute respiratory syndrome (Severe Acute Respiratory Syndrome) related pathogenesis and vaccines have not yet made breakthrough progress, the main way to prevent the spread of this malignant infectious disease is to block its effective transmission route, and air sterilization is one of the more effective means."

"supplying chlorine dioxide gas into a space where floating virus can be present by a gas concentration which allows the animal to live or stay, but deactivates the virus."

****!!!!!***** Using a methodology that can maintain low chlorine dioxide concentration in air even under high humidity, examined the effect of humidity on airborne influenza virus inactivation at a very low gas concentration. It was shown that chlorine dioxide at less than 0.02-0.03 ppm has an ability to inactivate airborne influenza virus under 50% and 70% RH conditions. However, from a viewpoint of infection control, these researchers believed it is a minor effect which is merely additional to the major effect by the humidity itself, when considering the actual load of viruses released from an influenza patient in a room space and still active after certain time. Low concentrations of chlorine dioxide also make much less difference under 30% relative humidity levels common in winter." Original paper https://www.semanticscholar.org/paper/Inactivation-of-Airborne-Influenza-Virus-Using-Low-Nishimura-Hayashi/3cc74aad740dc6e036e76a3e4fdaee02a159a309 https://pdfs.semanticscholar.org/3cc7/4aad740dc6e036e76a3e4fdaee02a159a309.pdf