****!!!!**** "Our clinical study showed that EBD [ethanol-based disinfectants] effectiveness against IAV [influenza A virus] in mucus was extremely reduced compared to IAV in saline. IAV in mucus remained active despite 120 s of AHR; however, IAV in saline was completely inactivated within 30 s. Due to the low rate of diffusion/convection because of the physical properties of mucus as a hydrogel, the time required for the ethanol concentration to reach an IAV inactivation level and thus for EBDs to completely inactivate IAV was approximately eight times longer in mucus than in saline. On the other hand, AHR inactivated IAV in mucus within 30 s when the mucus dried completely because the hydrogel characteristics were lost. Additionally, AHW [antiseptic hand washing] rapidly inactivated IAV. Until infectious mucus has completely dried, infectious IAV can remain on the hands and fingers, even after appropriate AHR [antiseptic hand rubbing] using EBD, thereby increasing the risk of IAV transmission. We clarified the ineffectiveness of EBD use against IAV in infectious mucus." "IMPORTANCE Antiseptic hand rubbing (AHR) and antiseptic hand washing (AHW) are important to prevent the spread of influenza A virus (IAV). This study elucidated the situations/mechanisms underlying the reduced efficacy of AHR against infectious mucus derived from IAV-infected individuals and indicated the weaknesses of the current hand hygiene regimens. Due to the low rate of diffusion/convection because of the physical properties of mucus as a hydrogel, the efficacy of AHR using ethanol-based disinfectant against mucus is greatly reduced until infectious mucus adhering to the hands/fingers has completely dried. If there is insufficient time before treating the next patient (i.e., if the infectious mucus is not completely dry), medical staff should be aware that effectiveness of AHR is reduced. Since AHW is effective against both dry and nondry infectious mucus, AHW should be adopted to compensate for these weaknesses of AHR."

***A 10-week, open-label, crossover study was performed on 420 elementary school-age children. Students were given a brief orientation immediately prior to the start of the study on the relationship of germs, illness, and hand washing. Each student in the treatment group then received the test product in individual bottles, with instructions to apply one to two ***sprays to the hands*** after coming into the classroom, before eating, and after using the restroom, in addition to their normal hand washing with soap and water... After 4 weeks of treatment and a 2-week wash-out period, the control and experimental groups were reversed. Data gathered on absenteeism were classified as gastrointestinal or respiratory related and normalized for nonillness-related absenteeism and school holidays. ** RESULTS: Compared to the hand washing-only control group, students using CleanHands were found to have 41.9% fewer illness-related absence days, representing a 28.9% and a 49.7% drop in gastrointestinal- and respiratory-related illnesses, respectively. Likewise, absence incidence decreased by 31.7%, consisting of a 44.2% and 50.2% decrease in incidence of gastrointestinal- and respiratory-related illnesses, respectively.

Hand sanitizer must ***only*** contain ethanol alcohol, isopropyl alcohol, Glycerin, Hydrogen peroxide, sterile water

{Advantages} Hand sanitisers for infection prevention. Help and information on choosing the right hand sanitiser for your needs.

Chemical enhanced oil recovery (EOR) and particularly surfactant injection has recently received a great deal of attention. The suggested recovery mec…

Water, sanitation and hygiene interventions (WASH) are commonly implemented as part of emergency response activities (i.e. in response to disease outbreaks) in low and middle-income countries. But what does the existing evidence tell us about what works? How does the use of WASH interventions reduce disease outbreaks? What are the programme design and implementation characteristics associated with more effective programmes? What is the cost effectiveness of WASH interventions in emergency outbreak situations? What are the barriers and facilitators to WASH interventions in outbreaks? This ev...

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