"Why Use CloSYS or ProFresh? The chlorine dioxide ingredient in both products offers 2 benefits. It complements Listerine by more effectively killing the oxygen hating anaerobic bacteria. Focus on bathing your back teeth and tongue. This is where anaerobic bacteria live, and deeper pockets usually form around your back teeth first."

"One mouth rinse growing in use and popularity among cancer patients contains stabilized chlorine dioxide (SCD)and has shown no adverse side effects. This article presents the results of patient interviews conducted to determinethe effectiveness of SCD products in alleviating medically-induced oral mucositis. Included are 5 case histories thatreflect positive, yet diverse, experiences of cancer patients using SCD oral health products during, and after, theircancer treatments"

A sinus flush, or nasal irrigation, is one way to clear out your sinuses at home. All you need is a saline solution and a neti pot or bulb syringe. We'll explain how to do a sinus flush and safety tips.

This literature review supports the use of phosphate buffer-stabilized 0.1% chlorine dioxide mouthrinse in the management of MRONJ lesions

{Dental White & Fresh mouthwash} Sodium chlorite: "The general toxicological findings found : acute oral LD 50 = 150 mg/kg, chronic no effect level = 7.4 mg/kg, chronic mild effect level = 19 mg/kg. Based on these data, a normal use pattern of a mouthrinse product (5,000 mg/L NaCLO2 concentration-about5 times the amount in Dental White & Fresh), 3x per day, 90% expectoration) for a 150 lb person maintains a > 150 fold safety margin for acute toxicity effects."

White Papers and Studies available on Frontier's Active Chlorine Dioxide Mouthwash, Toothpaste, Periodontal Gel, and other DioxiCare® products.

BACKGROUND: COVID-19 infection poses a serious risk to patients and - due to its contagious nature - to those healthcare workers (HCWs) treating them. If the mouth and nose of patients with...

DioxiCare System developed by Howard Alliger, founder of Frontier & pioneer in the chemistry of chlorine dioxide. first to patent chlorine dioxide for use on the body,1978. Company now led by his daughter Valerie. "If interested in learning more about this research, feel free to contact us. "

{Full paper} {Probably Solonium} "First of all, it is used to disinfect the root canal instead of sodium hypochlorite, but it is also used to treat aphthous, herpes and other oral infections and to reduce inflammation. The positive experiences are reported in a series of articles published in Dental News in 2009. In our opinion, in the near future, hyperpure chlorine dioxide will have many other applications in addition to dentistry as medical, hospital and industrial disinfectants."

****!!!**** "medicines (drugs) or medical devices may be used for the treatment (prevention, alleviation, etc.) of human diseases. A drug penetrates inside the body, and influences the processes within the human tissues. However, hyperpure chlorine dioxide is not able to penetrate into the human body but exerts its antimicrobial action only on its surface, against microbial biofims, for example. Therefore, Solumium solutions are not drugs but *******medical devices." full bottle (30ml) of Solumium Dental contains 36 mg of chlorine dioxide. "In root canal treatment... highly volatile Solumium Dental evaporates into any air bubbles, and goes on eliminating the bacteria in the whole treated area." "Daily dose of 24 mg of chlorine dioxide has no clinically or in any other way measurable effect on the human body."

***********SARS-CoV-2 --"“ClO2 impacts the coronavirus by its rapid reaction with three of the twenty amino acid residues, cysteine, tyrosine, and tryptophan, found in all protein chains, while essentially not reacting with the others. Since the spike protein contains all three, this could be an important point of attack; their oxidation changes the entire spatial structure of the protein, leading to denaturation." "Sodium chlorite (NaClO2) solution is often wrongly referred to as chlorine dioxide, which was the case with the internally used and harmful MMS drops. Sodium chlorite is absorbed differently from chlorine dioxide, and can reach the kidneys and the liver. In small quantities its toxic effect causes vomiting and diarrhoea, while in larger doses it may lead to kidney failure" "Immune response... takes 8-12 days and if, during this critical phase, too many coronaviruses reach the lungs, reproducing rapidly on its mucous membrane, this may induce a strong and often fatal immune response, called the cytokine storm”. People infected may also inhale the aerosol particles again,"

!! "Results showed *5.25% NaOCl to be most effective* (at dissolving tissue) at both time intervals followed by 2.5% NaOCl at 60 minutes, 10%Ca(OCl)2 and 13% ClO2 at 60 minutes. Least amount of tissue dissolving ability was demonstrated by 5% Ca(OCl)2 and 5% ClO2 at 30 minutes." *****"Mean tissue dissolution by ClO2 was significantly less than NaOCl. The reason for this might also be the low pH of ClO2 as compared to high pH (pH = 12) of NaOCl. In a study by Nishikiori et al,[18] the pH of ClO2 was raised upto 12 by using NaOH and it was found equivalent to NaOCl for dissolving bovine pulp tissue. But according to Deininger et al.[19] ClO2 exhibits biocidal efficacy only over a pH range of 3-9. Between pH 4-7, chlorine exists predominantly as HClO, the active moiety responsible for bacterial inactivation, whereas above pH 9, OCl− predominates.[20] Also the addition of NaOH will result in making the aqueous solution of ClO2 ineffective by breaking it down into sodium chlorate, sodium chlorite and water. Among the ClO2 group, large amount of mean tissue dissolution was demonstrated by 13% ClO2 at 60 minutes.5% ClO2 showed lower pulp dissolving capacity at 30 minutes, followed by 5% ClO2 at 60 minutes and 13% ClO2 at 30 minutes, which were comparable. *****Studies have suggested that !!!!!!!lower the pH !!!!, more time was needed for solution contact for tissue dissolution.***** [6] This might be the reason for less effectiveness of ClO2 in dissolution of pulp tissue at 30 minutes than at 60 minutes. "

"...Further studies are also required to protect teeth, the surface of hydroxyapatite-coated implants, and the surrounding soft tissues from effects of chemical dissolution such as acid erosion due to the low pH of ASC-Gel. "

OraCare’s Activated Oral Cleanser -chlorine dioxide

View lab results from an in vitro laboratory analysis with CloSYS Ultra Sensitive Oral Rinse and COVID-19 virus. Reduced SARS-CoV-2 (COVID-19 virus) by 98.4 percent.

{CloSys}

"Cetylpyridinium chloride is a simple molecule that is cheap, safe, clinically approved, widely accessible in hospitals and the consumer sector and which could enter clinical trials immediately. If reported to have activity in vitro against SARS-CoV-2 subsequent delivery in the form of a mouthwash or nasal spray containing this compound may be an effective way both to combat the virus at its point of entry and reduce SARS-CoV-2 transmission. Similarly, this compound could be added to shampoo and body cleansers so that one could effectively bathe in low concentrations of this compound to destroy shed coronavirus."

{Includes use of ethanol} The oral cavity, an essential part of the upper aerodigestive tract, is believed to play an important role in the pathogenicity and transmission of SARS-CoV-2. The identification of targeted antiviral mouth rinses to reduce salivary viral load would contribute ...

Chlorine dioxide (ClO[2] ) has been recently investigated as a possible root canal irrigant due to its broad spectrum of antimicrobial action, tissue dissolution and smear layer removal properties. Literature is scarce on the effect of chlorine dioxide ...

***** {OraCare} "Activated chlorine dioxide" "Simply stated, it strips off more than twice as many electrons from a pathogen. This occurs in a two-step process: First, the reaction causes chlorine dioxide to be reduced to sodium chlorite. Then the sodium chlorite is reduced to sodium chloride, or ordinary table salt and water, which are harmless. The chlorine molecule remains in the substance until the end; that’s why chlorine dioxide does not produce harmful chlorinated substances such as trihalomethanes."

(2020)

Request PDF | Influence of chlorine dioxide on cell death and cell cycle of human gingival fibroblasts | The effects of chlorine dioxide (ClO2), sodium hypochlorite (NaOCl), and hydrogen peroxide (H2O2) on cell death and the cell cycle of human... | Find, read and cite all the research you need on ResearchGate

{CloSYS brand} This in vitro study evaluated the effectiveness of a novel dentifrice containing stabilized chlorine dioxide, sodium lauroyl sarcosinate (sarkosyl), and sodium fluoride in enhancing enamel fluoride uptake, remineralization, pellicle cleaning and inhibiting biofilm regrowth.

**** "The retention of these products' active agent, i.e. greater than 10% of ClO2-, is consumed by HSS biomolecules within recommended 30 second oral rinsing episodes, and hence, the bulk of this oxyhalogen ocidant (greater than 90%) may effectively exert its essential microbicidal, anti-periodontal and oral molodour-neutralising actions."

******* Salivary biomolecules which chemically react with oral rinse oxidant can, at least in principle, serve as potentially significant barriers to these therapeutic properties in the oral environment. Therefore, in this investigation, we have explored the extent of ClO2− consumption by biomolecules which scavenge this agent in human salivary supernatants (HSSs) in vitro.

******{Nasal flushing with Snoot! or DioxiRinse}