Ivermectin is an FDA-approved broad-spectrum anti-parasitic agent that has been shown to inhibit SARS-CoV-2 replication in vitro.We aimed to assess the therapeutic efficacy of ivermectin mucoadhesive nanosuspension intranasal spray in treatment of patients ...

{benzalkonium} "its patented nanotechnology, which uses oil-in-water nano-droplets for products applied to the skin and nose. The droplets are small enough to be applied to the skin, the company says, but too large to get into the bloodstream." ""It's approved for use by the FDA as a treatment to kill germs on the skin," Dr. Costley said of the company’s nanotechnology. "As long as we stay within the FDA guidelines, we're approved for uses in the United States.""

{Testing of nasal rinses and mouthwashes against COVID-19}

To provide a narrative review of the preprocedural mouth rinse protocols suggested for oral surgery in order to contrast the presence of SARS-CoV-2 in aerosol.Electronic searches were performed in medical databases PubMed, Medline, CINAHN and Scopus to ...

SARS‐CoV‐2 RNA has been recovered from different sites in the human body, including the mouth. The present study aimed to investigate the presence of SARS‐CoV‐2 RNA in the dental biofilm of symptomatic patients who tested ...

Dental professionals work closely with patients and present an increased risk of person-to-person transmission of SARS-CoV-2. Moreover, the use of ultrasonic scalers, air–water syringes, and slow and high-speed handpieces, which are common in ...

The SARS-CoV-2 virus has given birth to several other new diseases. One of the rapidly spreading infection post-COVID recoveries is black fungus.

As we face the challenge of coping with COVID-19 and the emergence of more transmissible and deadly strains of the

"Cetylpyridinium chloride is a simple molecule that is cheap, safe, clinically approved, widely accessible in hospitals and the consumer sector and which could enter clinical trials immediately. If reported to have activity in vitro against SARS-CoV-2 subsequent delivery in the form of a mouthwash or nasal spray containing this compound may be an effective way both to combat the virus at its point of entry and reduce SARS-CoV-2 transmission. Similarly, this compound could be added to shampoo and body cleansers so that one could effectively bathe in low concentrations of this compound to destroy shed coronavirus."

A low irritation nasal composition for the prevention and treatment of cold and flu viruses comprising pyroglutamic acid and an organic acid having a dissociation constant (pKa) value of 3.0 to 5.0. wherein the composition has a pH of less than 4, 5 and the combination of said pyroglutamic and organic acids provides a superficial pH of the nasal cavity tissue of pH 3, 5 to 5, 5.

To reduce inflammation and improve breathing. The disclosure is also related to a composition for freshening and cleansing the sinus cavities and nostrils that includes a homeopathic ingredient and saline carrier solution. The disclosure is also related to the use of such composition to provide many anticipated and unexpected benefits that emanate from cleansing debris and microbes from the sinuses and nostrils.

PDF | Aims and Objectives: Ventilator-associated pneumonia is associated with increased morbidity and mortality. The aim of this pilot study was to... | Find, read and cite all the research you need on ResearchGate

"In the setting of MRSA endemicity, the prevention of MRSA carriage by topical oropharyngeal vancomycin was more effective in reducing carriage and infection of the lower airways than treatment of established carriers."

***** "The authors believe that the topical application of PVP‐I is safe and may help to reduce the viral load, and the potential aerosolization, of SARS‐CoV‐2. Until confirmatory studies are conducted, our institutional consensus is to dilute commonly available PVP‐I (typically 7.5%) 1:3 with saline to achieve a less than 2% concentration and bulb syringe the solution into the oral/nasal cavity, after intubation, but immediately prior to head and neck procedures that require instrumentation of the upper airway mucosa during the COVID‐19 pandemic. We suggest leaving the solution in for approximately 1 minute before irrigating with saline and suctioning it out to reduce residual absorption and limit tissue staining – though the optimal concentration and application time, if any, are currently unknown."

If the mist in a dentist's office -- sent flying into the air by spinning, vibrating tools -- contains a virus or some other pathogen, it is a health hazard. So researchers studied the viscoelastic properties of food-grade polymers and discovered that the forces of a vibrating tool or dentist's drill are no match for them. Not only did a small admixture of polymers completely eliminate aerosolization, but it did so with ease.

{Includes use of ethanol} The oral cavity, an essential part of the upper aerodigestive tract, is believed to play an important role in the pathogenicity and transmission of SARS-CoV-2. The identification of targeted antiviral mouth rinses to reduce salivary viral load would contribute ...

A sinus flush, or nasal irrigation, is one way to clear out your sinuses at home. All you need is a saline solution and a neti pot or bulb syringe. We'll explain how to do a sinus flush and safety tips.