C Diff Molecular

C Diff Molecular

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MICROBIOME: the kingdom of the gut
MICROBIOME: the kingdom of the gut
Meet your gut microbiome: a community of around 4,500 different types of bacteria living in your bowels
·cam.ac.uk·
MICROBIOME: the kingdom of the gut
Absence of Toll-like Receptor 7 Ameliorates Survival and Reduces Intestinal Injury in Mice after Clostridium difficile Infection - PubMed
Absence of Toll-like Receptor 7 Ameliorates Survival and Reduces Intestinal Injury in Mice after Clostridium difficile Infection - PubMed
Clostridioides difficile (CD) is a major cause of antibiotic-associated diarrhea and pseudomembranous enteritis. C. difficile infection (CDI) is increasingly present in the community and represents a significant burden on the healthcare system. Identification of novel immune-based therapeutic target …
·pubmed.ncbi.nlm.nih.gov·
Absence of Toll-like Receptor 7 Ameliorates Survival and Reduces Intestinal Injury in Mice after Clostridium difficile Infection - PubMed
Your height may influence the diversity of your gut microbiome
Your height may influence the diversity of your gut microbiome
Taller people may have longer gastrointestinal tracts that can house a broader array of microorganisms and could protect them against infections from bacteria such as Clostridium difficile
·news.google.com·
Your height may influence the diversity of your gut microbiome
Is Dysbiotic Gut the Cause of Low Back Pain? - PubMed
Is Dysbiotic Gut the Cause of Low Back Pain? - PubMed
Low back pain (LBP) is the foremost cause of disability that affects the day-to-day activities of millions of people worldwide. The putative trigger of LBP is linked to the gut microbiome (GM) and its dysbiotic environment. With the concept of GM, various disease pathogenesis has been revisited with …
·pubmed.ncbi.nlm.nih.gov·
Is Dysbiotic Gut the Cause of Low Back Pain? - PubMed
Dual RNA-seq identifies genes and pathways modulated during Clostridioides difficile colonization - PubMed
Dual RNA-seq identifies genes and pathways modulated during Clostridioides difficile colonization - PubMed
The gastrointestinal pathogen Clostridioides difficile is the most common cause of hospital-acquired diarrhea. Bacterial interactions with the gut mucosa are crucial for the establishment of C. difficile infection; however, key infection events like bacterial attachment and gut penetra …
·pubmed.ncbi.nlm.nih.gov·
Dual RNA-seq identifies genes and pathways modulated during Clostridioides difficile colonization - PubMed
Dual RNA-seq identifies genes and pathways modulated during Clostridioides difficile colonization - PubMed
Dual RNA-seq identifies genes and pathways modulated during Clostridioides difficile colonization - PubMed
The gastrointestinal pathogen Clostridioides difficile is the most common cause of hospital-acquired diarrhea. Bacterial interactions with the gut mucosa are crucial for the establishment of C. difficile infection; however, key infection events like bacterial attachment and gut penetra …
·pubmed.ncbi.nlm.nih.gov·
Dual RNA-seq identifies genes and pathways modulated during Clostridioides difficile colonization - PubMed
Role of the Alteration in Calcium Homeostasis in Cell Death Induced by Clostridioides difficile Toxin A and Toxin B - PubMed
Role of the Alteration in Calcium Homeostasis in Cell Death Induced by Clostridioides difficile Toxin A and Toxin B - PubMed
Clostridioides difficile (C. difficile), responsible for 15-25% of gastrointestinal infections, causes health problems mainly due to the toxic activity of toxins A and B (Tcds). These are responsible for its clinical manifestations, including diarrhea, pseudomembranous colitis, toxic m …
·pubmed.ncbi.nlm.nih.gov·
Role of the Alteration in Calcium Homeostasis in Cell Death Induced by Clostridioides difficile Toxin A and Toxin B - PubMed
Microbiota in Irritable Bowel Syndrome and Endometriosis: Birds of a Feather Flock Together-A Review - PubMed
Microbiota in Irritable Bowel Syndrome and Endometriosis: Birds of a Feather Flock Together-A Review - PubMed
Endometriosis and irritable bowel syndrome (IBS) are chronic conditions affecting up to 10% of the global population, imposing significant burdens on healthcare systems and patient quality of life. Interestingly, around 20% of endometriosis patients also present with symptoms indicative of IBS. The …
·pubmed.ncbi.nlm.nih.gov·
Microbiota in Irritable Bowel Syndrome and Endometriosis: Birds of a Feather Flock Together-A Review - PubMed
Analyses of cell wall synthesis in Clostridioides difficile reveal a diversification in cell division mechanisms in endospore-forming bacteria - PubMed
Analyses of cell wall synthesis in Clostridioides difficile reveal a diversification in cell division mechanisms in endospore-forming bacteria - PubMed
Current models of bacterial cell division assume that the core synthases of the multiprotein divisome complex, FtsW-FtsI, are the primary drivers of septal peptidoglycan (PG) synthesis. These enzymes are typically encoded in the highly conserved division and cell wall ( dcw ) cluster and are …
·pubmed.ncbi.nlm.nih.gov·
Analyses of cell wall synthesis in Clostridioides difficile reveal a diversification in cell division mechanisms in endospore-forming bacteria - PubMed
Diarrheal-associated gut dysbiosis in cancer and inflammatory bowel disease patients is exacerbated by Clostridioides difficile infection - PubMed
Diarrheal-associated gut dysbiosis in cancer and inflammatory bowel disease patients is exacerbated by Clostridioides difficile infection - PubMed
Our data indicate that different external and internal factors drive comparable profiles of low diversity dysbiosis. While diarrheal-related low diversity dysbiosis may be a consequence of systemic cancer therapy, a similar phenotype is observed in cases of moderate to severe IBD, and in both cases, …
·pubmed.ncbi.nlm.nih.gov·
Diarrheal-associated gut dysbiosis in cancer and inflammatory bowel disease patients is exacerbated by Clostridioides difficile infection - PubMed
Case report of SARS-CoV-2 with secondary Clostridioides difficile infection - PubMed
Case report of SARS-CoV-2 with secondary Clostridioides difficile infection - PubMed
There has been an overuse of antibiotics in most patients suffering from COVID-19 which predisposes patients to hospital acquired C. difficile Infection (CDI). Also, COVID infection of the gastrointestinal tract also predisposes the patient to CDI. We here present a fatal case of SARS-CoV-2 coinfect …
·pubmed.ncbi.nlm.nih.gov·
Case report of SARS-CoV-2 with secondary Clostridioides difficile infection - PubMed
Clostridioides difficile and Enterococci's Interplay in the Human Gut: Bacterial Alliance or Competition? A Systematic Literature Review - PubMed
Clostridioides difficile and Enterococci's Interplay in the Human Gut: Bacterial Alliance or Competition? A Systematic Literature Review - PubMed
Clostridioides difficile and Enterococcus spp. are two common bacterial pathogens populating the human microbiota. We possess scant data on how Clostridioides difficile interacts with Enterococcus spp. in the gut microbiota in subjects colonized with Clostridioides dif …
·pubmed.ncbi.nlm.nih.gov·
Clostridioides difficile and Enterococci's Interplay in the Human Gut: Bacterial Alliance or Competition? A Systematic Literature Review - PubMed
Case report of SARS-CoV-2 with secondary Clostridioides difficile infection - PubMed
Case report of SARS-CoV-2 with secondary Clostridioides difficile infection - PubMed
There has been an overuse of antibiotics in most patients suffering from COVID-19 which predisposes patients to hospital acquired C. difficile Infection (CDI). Also, COVID infection of the gastrointestinal tract also predisposes the patient to CDI. We here present a fatal case of SARS-CoV-2 coinfect …
·pubmed.ncbi.nlm.nih.gov·
Case report of SARS-CoV-2 with secondary Clostridioides difficile infection - PubMed
Characterization of the Gut Microbiome in Healthy Dogs and Dogs with Diabetes Mellitus - PubMed
Characterization of the Gut Microbiome in Healthy Dogs and Dogs with Diabetes Mellitus - PubMed
With a close pathogenetic resemblance to human diabetes, canine Diabetes Mellitus, a chronic metabolic disease featuring abnormally high blood sugar levels, is increasing in prevalence worldwide. Unlike humans, canine glycemic control requires life-long insulin injections and dietary control in most …
·pubmed.ncbi.nlm.nih.gov·
Characterization of the Gut Microbiome in Healthy Dogs and Dogs with Diabetes Mellitus - PubMed
Clostridioides difficile Infection in Inflammatory Bowel Disease Patients: A Systematic Review of Risk Factors and Approach in Management
Clostridioides difficile Infection in Inflammatory Bowel Disease Patients: A Systematic Review of Risk Factors and Approach in Management
Clostridioides difficile infection (CDI) is one of the most common diseases associated with medical care, having a more significant impact on patients with inflammatory bowel disease (IBD). The latest studies have proposed a change in management for CDI in IBD patients. This study aims to perform a systematic review that explores the risk factors associated with the infection and the most optimal approach in management. Multiple databases were used for this research, including PubMed, Google Scholar, Science Direct, and Cochrane Library. Studies published in the last five years in the English language were selected based on pre-established criteria. The quality assessment used was the Assessment of Multiple Systematic Review, the Newcastle-Ottawa Scale, and the Scale for the Assessment of Narrative Review Articles. Twelve studies met the inclusion criteria in this systematic review, including literature reviews, a case and control study, and systematic reviews and meta-analyses. Based on the findings in this research, we conclude that the treatment for an initial episode of CDI in IBD patients is the use of antibiotics, vancomycin, or fidaxomicin. For episodes of recurrent CDI (rCDI), fetal microbiota transplantation should be considered. The most common risk factors associated are gut microbiota disturbances, the use of antibiotics, and hospitalization. Due to a wide range of risk factors mentioned in some studies but disregarded in others, further research is needed to determine the most prevalent risk factors.
·cureus.com·
Clostridioides difficile Infection in Inflammatory Bowel Disease Patients: A Systematic Review of Risk Factors and Approach in Management
Ulcerative colitis induced by paraneoplastic syndrome | JIR
Ulcerative colitis induced by paraneoplastic syndrome | JIR
Paraneoplastic syndromes often cause endocrine, neurological, cutaneous, and hematologic pathologies, and cases with digestive symptoms as prominent are rare.
·news.google.com·
Ulcerative colitis induced by paraneoplastic syndrome | JIR
Mucosal-associated invariant T (MAIT) cells from Clostridioides difficile-infected patients exhibit a distinct proinflammatory phenotype and enhanced cytotoxic activity - PubMed
Mucosal-associated invariant T (MAIT) cells from Clostridioides difficile-infected patients exhibit a distinct proinflammatory phenotype and enhanced cytotoxic activity - PubMed
Mucosal-associated invariant T (MAIT) cells are innate-like T cells mainly found in the mucosa and peripheral blood. We have recently demonstrated that Clostridioides difficile activates MAIT cell in vitro. However, their role in the pathogenesis of C. difficile infection (CDI) in human patients rem …
·pubmed.ncbi.nlm.nih.gov·
Mucosal-associated invariant T (MAIT) cells from Clostridioides difficile-infected patients exhibit a distinct proinflammatory phenotype and enhanced cytotoxic activity - PubMed
The microbial metabolite Urolithin A reduces C. difficile toxin expression and repairs toxin-induced epithelial damage - PubMed
The microbial metabolite Urolithin A reduces C. difficile toxin expression and repairs toxin-induced epithelial damage - PubMed
Therapy for C. difficile infections includes the use of antibiotics, immunosuppressors, and fecal microbiota transplantation (FMT). However, these treatments have several drawbacks, including the loss of colonization resistance, promotion of autoimmune disorders, and the potential for unknown …
·pubmed.ncbi.nlm.nih.gov·
The microbial metabolite Urolithin A reduces C. difficile toxin expression and repairs toxin-induced epithelial damage - PubMed
Mucosal-associated invariant T (MAIT) cells from Clostridioides difficile-infected patients exhibit a distinct proinflammatory phenotype and enhanced cytotoxic activity - PubMed
Mucosal-associated invariant T (MAIT) cells from Clostridioides difficile-infected patients exhibit a distinct proinflammatory phenotype and enhanced cytotoxic activity - PubMed
Mucosal-associated invariant T (MAIT) cells are innate-like T cells mainly found in the mucosa and peripheral blood. We have recently demonstrated that Clostridioides difficile activates MAIT cell in vitro. However, their role in the pathogenesis of C. difficile infection (CDI) in human patients rem …
·pubmed.ncbi.nlm.nih.gov·
Mucosal-associated invariant T (MAIT) cells from Clostridioides difficile-infected patients exhibit a distinct proinflammatory phenotype and enhanced cytotoxic activity - PubMed
The predicted acetoin dehydrogenase pathway represses sporulation of Clostridioides difficile - PubMed
The predicted acetoin dehydrogenase pathway represses sporulation of Clostridioides difficile - PubMed
Clostridioides difficile, or C. diff , is an anaerobic bacterium that lives within the gut of many mammals and causes infectious diarrhea. C. difficile is able to survive outside of the gut and transmit to new hosts by forming dormant spores. It is known that the pH of the intes …
·pubmed.ncbi.nlm.nih.gov·
The predicted acetoin dehydrogenase pathway represses sporulation of Clostridioides difficile - PubMed