C Diff Molecular

C Diff Molecular

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Clostridioides difficile SpoVAD and SpoVAE interact and are required for DPA uptake into spores
Clostridioides difficile SpoVAD and SpoVAE interact and are required for DPA uptake into spores
Clostridioides difficile spores, like the spores from most endospore-forming organisms, are a metabolically dormant stage of development with a complex structure that conveys considerable resistance to environmental conditions, e.g., wet heat. This resistance is due to the large amount …
·pubmed.ncbi.nlm.nih.gov·
Clostridioides difficile SpoVAD and SpoVAE interact and are required for DPA uptake into spores
VirB4- and VirD4-like ATPases, components of a putative type 4C secretion system in Clostridioides difficile
VirB4- and VirD4-like ATPases, components of a putative type 4C secretion system in Clostridioides difficile
The type 4 secretion system (T4SS) represents a bacterial nanomachine capable of trans-cell wall transportation of proteins and DNA and has attracted intense interest due to its roles in the pathogenesis of infectious diseases. In the current investigation, we uncovered three distinct gene clusters …
·pubmed.ncbi.nlm.nih.gov·
VirB4- and VirD4-like ATPases, components of a putative type 4C secretion system in Clostridioides difficile
alpha-galactosylceramide-reactive NKT cells increase IgG1 class switch against a C. difficile polysaccharide antigen and enhance immunity against a live pathogen challenge
alpha-galactosylceramide-reactive NKT cells increase IgG1 class switch against a C. difficile polysaccharide antigen and enhance immunity against a live pathogen challenge
All clinical Clostridioides difficile strains identified to date express a surface capsule-like polysaccharide structure known as polysaccharide II (PSII). The PSII antigen is immunogenic and when conjugated to a protein carrier induces a protective antibody response in animal models. Given t …
·pubmed.ncbi.nlm.nih.gov·
alpha-galactosylceramide-reactive NKT cells increase IgG1 class switch against a C. difficile polysaccharide antigen and enhance immunity against a live pathogen challenge
RT @MicroMindy: Its been so great seeing all the #biofilmweek images! It inspired me throw this one into the mix- here is a SEM of C. diffi…
RT @MicroMindy: Its been so great seeing all the #biofilmweek images! It inspired me throw this one into the mix- here is a SEM of C. diffi…
Its been so great seeing all the #biofilmweek images! It inspired me throw this one into the mix- here is a SEM of C. difficile and F. nucleatum biofilms! #biofilmsinthelab #biofilm #Cdiff #Fusobacterium pic.twitter.com/1rPPpJse7q— Mindy Engevik (@MicroMindy) August 21, 2021
·twitter.com·
RT @MicroMindy: Its been so great seeing all the #biofilmweek images! It inspired me throw this one into the mix- here is a SEM of C. diffi…
Invisible steps for a global endemy: molecular strategies adopted by Clostridioides difficile
Invisible steps for a global endemy: molecular strategies adopted by Clostridioides difficile
Clostridioides difficile infection (CDI) is on the rise worldwide and is associated with an increase in deaths and socio-health burden. C. difficile has become ubiquitous in anthropized environments because of the extreme resistance of its spores. Based on the epidemiological data and …
·pubmed.ncbi.nlm.nih.gov·
Invisible steps for a global endemy: molecular strategies adopted by Clostridioides difficile
Characterization of an operon required for growth on cellobiose in Clostridioides difficile
Characterization of an operon required for growth on cellobiose in Clostridioides difficile
Cellobiose metabolism is linked to the virulence properties in numerous bacterial pathogens. Here, we characterized a putative cellobiose PTS operon of Clostridiodes difficile to investigate the role of cellobiose metabolism in C. difficile pathogenesis. Our gene knockout experiments d …
·pubmed.ncbi.nlm.nih.gov·
Characterization of an operon required for growth on cellobiose in Clostridioides difficile
Blastocystis and Clostridioides difficile: Evidence for a Synergistic Role in Colonization Among IBD Patients with Emphasis on Ulcerative Colitis
Blastocystis and Clostridioides difficile: Evidence for a Synergistic Role in Colonization Among IBD Patients with Emphasis on Ulcerative Colitis
The co-existence of Blastocystis and C. difficile in IBD patients was observed in the current study. Moreover, it can be proposed that these microorganisms may have synergistic effects on their colonization in the gastrointestinal tract.
·pubmed.ncbi.nlm.nih.gov·
Blastocystis and Clostridioides difficile: Evidence for a Synergistic Role in Colonization Among IBD Patients with Emphasis on Ulcerative Colitis
Does caloric restriction prime the microbiome for pathogenic bacteria?
Does caloric restriction prime the microbiome for pathogenic bacteria?
A recent study in Nature finds significant shifts in the gut microbiome of post-menopausal women on severe calorie restriction concomitant with weight loss. Microbiota transplantation to germ-free mice display a similar weight loss, along with a bloom in C. difficile, unlocking clues to microbial metabolic alteration in weight loss.
·cell.com·
Does caloric restriction prime the microbiome for pathogenic bacteria?
Get the C Diff App
Get the C Diff App
It takes less than a minute to download C diff and You app.Available from the Apple Store and Google Play Store 📱We place the C. diff. community in the palm of your hands 🤲 #cdiff #CDI #Cdifficile #healthcare #clinicaltrials #nutrition #support #microbiome #Cdiffeducation pic.twitter.com/EaXHWJaYA7— C DIFF FOUNDATION (@cdiffFoundation) August 9, 2021
·twitter.com·
Get the C Diff App
Complete Genome Assemblies of Three Highly Prevalent, Toxigenic Clostridioides difficile Strains Causing Health Care-Associated Infections in Australia
Complete Genome Assemblies of Three Highly Prevalent, Toxigenic Clostridioides difficile Strains Causing Health Care-Associated Infections in Australia
Clostridioides difficile infection (CDI) is the leading cause of life-threatening health care-related gastrointestinal illness worldwide. Phylogenetically appropriate closed reference genomes are essential for studies of C. difficile transmission and evolution. Here, we provide high-quality complete …
·pubmed.ncbi.nlm.nih.gov·
Complete Genome Assemblies of Three Highly Prevalent, Toxigenic Clostridioides difficile Strains Causing Health Care-Associated Infections in Australia
What's a SNP between friends: The lineage of Clostridioides difficile R20291 can effect research outcomes
What's a SNP between friends: The lineage of Clostridioides difficile R20291 can effect research outcomes
Clostridioides difficile R20291 is the most studied PCR-Ribotype 027 isolate. The two predominant lineages of this hypervirulent strain, however, exhibit substantive phenotypic differences and possess genomes that differ by a small number of nucleotide changes. It is important that the source of R20 …
·pubmed.ncbi.nlm.nih.gov·
What's a SNP between friends: The lineage of Clostridioides difficile R20291 can effect research outcomes
Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians
Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians
Centenarians display decreased susceptibility to ageing-associated illness, chronic inflammation, and infectious disease1-3. Here we show that centenarians have a distinct gut microbiome enriched in microbes capable of generating unique secondary bile acids (BAs), including iso-, 3-oxo-, …
·pubmed.ncbi.nlm.nih.gov·
Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians
Colitis: Overview and More - Verywell Health
Colitis: Overview and More - Verywell Health
Colitis refers to inflammation in the colon (large intestine). There are many causes of colitis, some of which are serious and even life-threatening.
·verywellhealth.com·
Colitis: Overview and More - Verywell Health
Gutting to the chase on how bacteria adapts and functions – Monash Lens
Gutting to the chase on how bacteria adapts and functions – Monash Lens
Professor Dena Lyras, the first female ARC Laureate fellow in Monash University’s Faculty of Medicine, is on a continuing mission to understand the formidable enemy of antibiotic-resistant bacteria, particularly those in the human gut. Read more at Monash Lens
·lens.monash.edu·
Gutting to the chase on how bacteria adapts and functions – Monash Lens