C Diff Molecular

C Diff Molecular

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The complete catalog of antimicrobial resistance secondary active transporters in Clostridioides difficile: evolution and drug resistance perspective - PubMed
The complete catalog of antimicrobial resistance secondary active transporters in Clostridioides difficile: evolution and drug resistance perspective - PubMed
Secondary active transporters shuttle substrates across eukaryotic and prokaryotic membranes, utilizing different electrochemical gradients. They are recognized as one of the antimicrobial efflux pumps among pathogens. While primary active transporters within the genome of C. difficile 630 ha …
·pubmed.ncbi.nlm.nih.gov·
The complete catalog of antimicrobial resistance secondary active transporters in Clostridioides difficile: evolution and drug resistance perspective - PubMed
Decoding the role of immune T cells: A new territory for improvement of metabolic-associated fatty liver disease - PubMed
Decoding the role of immune T cells: A new territory for improvement of metabolic-associated fatty liver disease - PubMed
Metabolic-associated fatty liver disease (MAFLD) is a new emerging concept and is associated with metabolic dysfunction, generally replacing the name of nonalcoholic fatty liver disease (NAFLD) due to heterogeneous liver condition and inaccuracies in definition. The prevalence of MAFLD is rising by …
·pubmed.ncbi.nlm.nih.gov·
Decoding the role of immune T cells: A new territory for improvement of metabolic-associated fatty liver disease - PubMed
Genomic and phenotypic studies among Clostridioides difficile isolates show a high prevalence of clade 2 and great diversity in clinical isolates from Mexican adults and children with healthcare-associated diarrhea - PubMed
Genomic and phenotypic studies among Clostridioides difficile isolates show a high prevalence of clade 2 and great diversity in clinical isolates from Mexican adults and children with healthcare-associated diarrhea - PubMed
Clostridioides difficile is a toxin-producing bacterial pathogen recognized as the most common cause of diarrhea acquired primarily in healthcare settings. This bacterial species is diverse; its global population has been divided into five different clades using multilocus sequence typing, an …
·pubmed.ncbi.nlm.nih.gov·
Genomic and phenotypic studies among Clostridioides difficile isolates show a high prevalence of clade 2 and great diversity in clinical isolates from Mexican adults and children with healthcare-associated diarrhea - PubMed
Characterization and dynamics of intestinal microbiota in patients with Clostridioides difficile colonization and infection - PubMed
Characterization and dynamics of intestinal microbiota in patients with Clostridioides difficile colonization and infection - PubMed
Gut microbiota dysbiosis increases the susceptibility to Clostridioides difficile infection (CDI). In this study, we monitored C. difficile colonization (CDC) patients from no CDC status (CDN) to CDC status (CDCp) and CDI patients from asymptomatic status before CDI (PRECDI), CDI status (ONCDI), to …
·pubmed.ncbi.nlm.nih.gov·
Characterization and dynamics of intestinal microbiota in patients with Clostridioides difficile colonization and infection - PubMed
Gallic acid attenuates murine ulcerative colitis by promoting group 3 innate lymphocytes, affecting gut microbiota, and bile acid metabolism - PubMed
Gallic acid attenuates murine ulcerative colitis by promoting group 3 innate lymphocytes, affecting gut microbiota, and bile acid metabolism - PubMed
Gallic acid (GA), a plant phenol that is widely distributed in fruits and vegetables, and exhibits a protective role against ulcerative colitis (UC). UC is an inflammatory disease characterized by immune response disorders. However, the role and mechanism of action of GA in gut immunity remain unkno …
·pubmed.ncbi.nlm.nih.gov·
Gallic acid attenuates murine ulcerative colitis by promoting group 3 innate lymphocytes, affecting gut microbiota, and bile acid metabolism - PubMed
Clostridioides difficile-mucus interactions encompass shifts in gene expression, metabolism, and biofilm formation - PubMed
Clostridioides difficile-mucus interactions encompass shifts in gene expression, metabolism, and biofilm formation - PubMed
Clostridioides difficile results in upward of 250,000 infections and 12,000 deaths annually in the United States. Community-acquired infections continue to rise, and recurrent disease is common, emphasizing a vital need to understand C. difficile pathogenesis. C. difficile undou …
·pubmed.ncbi.nlm.nih.gov·
Clostridioides difficile-mucus interactions encompass shifts in gene expression, metabolism, and biofilm formation - PubMed
The role of extracellular structures in Clostridioides difficile biofilm formation - PubMed
The role of extracellular structures in Clostridioides difficile biofilm formation - PubMed
C. difficile infection (CDI) is a costly and increasing burden on the healthcare systems of many developed countries due to the high rates of nosocomial infections. Despite the availability of several antibiotics with high response rates, effective treatment is hampered by recurrent infections. One …
·pubmed.ncbi.nlm.nih.gov·
The role of extracellular structures in Clostridioides difficile biofilm formation - PubMed
Researchers solve mystery behind antibiotic-resistant C. difficile infection
Researchers solve mystery behind antibiotic-resistant C. difficile infection
Researchers at the Texas A&M University Health Science Center (Texas A&M Health) have uncovered why C. diff (also known as Clostridioides difficile or C. difficile) infection has developed resistance ...
·news.google.com·
Researchers solve mystery behind antibiotic-resistant C. difficile infection
Clostridioides difficile-mucus interactions encompass shifts in gene expression, metabolism, and biofilm formation - PubMed
Clostridioides difficile-mucus interactions encompass shifts in gene expression, metabolism, and biofilm formation - PubMed
Clostridioides difficile results in upward of 250,000 infections and 12,000 deaths annually in the United States. Community-acquired infections continue to rise, and recurrent disease is common, emphasizing a vital need to understand C. difficile pathogenesis. C. difficile undou …
·pubmed.ncbi.nlm.nih.gov·
Clostridioides difficile-mucus interactions encompass shifts in gene expression, metabolism, and biofilm formation - PubMed
Molecular Characterization and Potential Host-switching of Swine Farm associated Clostridioides difficile ST11 - PubMed
Molecular Characterization and Potential Host-switching of Swine Farm associated Clostridioides difficile ST11 - PubMed
Swine farm associated C. difficile ST11 carried fewer virulence genes than ST11 strains collected from NCBI database. It is critical to monitor the evolution of C. difficile strains to understand their changing characteristics, host-switching, and develop effective control and prevention strategies.
·pubmed.ncbi.nlm.nih.gov·
Molecular Characterization and Potential Host-switching of Swine Farm associated Clostridioides difficile ST11 - PubMed
Complete genome sequences of Clostridioides difficile surveillance isolates representing the top 10 ribotypes from the Emerging Infections Program, United States, 2016 - PubMed
Complete genome sequences of Clostridioides difficile surveillance isolates representing the top 10 ribotypes from the Emerging Infections Program, United States, 2016 - PubMed
Ten Clostridioides difficile isolates representing the top 10 ribotypes collected in 2016 through the Emerging Infections Program underwent long-read sequencing to obtain high-quality reference genome assemblies. These isolates are publicly available through the CDC & FDA Antibiotic Resis …
·pubmed.ncbi.nlm.nih.gov·
Complete genome sequences of Clostridioides difficile surveillance isolates representing the top 10 ribotypes from the Emerging Infections Program, United States, 2016 - PubMed
Goblet cells produce MUC5AC in response to C. difficile infection
Goblet cells produce MUC5AC in response to C. difficile infection
Based on findings from recent studies that have identified MUC5AC in mice infected with the nematode Trichuris trichiura and during colitis, researchers from Medical University of South Carolina aimed to assess the effects of Clostridioides difficile infection on MUC5AC in the intestinal mucosa.
·news.google.com·
Goblet cells produce MUC5AC in response to C. difficile infection
Exploring the Toxin-Mediated Mechanisms in Clostridioides difficile Infection - PubMed
Exploring the Toxin-Mediated Mechanisms in Clostridioides difficile Infection - PubMed
Clostridioides difficile infection (CDI) is the leading cause of nosocomial antibiotic-associated diarrhea, and colitis, with increasing incidence and healthcare costs. Its pathogenesis is primarily driven by toxins produced by the bacterium C. difficile, Toxin A (TcdA) and Toxin B (Tc …
·pubmed.ncbi.nlm.nih.gov·
Exploring the Toxin-Mediated Mechanisms in Clostridioides difficile Infection - PubMed
Exploring the Toxin-Mediated Mechanisms in Clostridioides difficile Infection - PubMed
Exploring the Toxin-Mediated Mechanisms in Clostridioides difficile Infection - PubMed
Clostridioides difficile infection (CDI) is the leading cause of nosocomial antibiotic-associated diarrhea, and colitis, with increasing incidence and healthcare costs. Its pathogenesis is primarily driven by toxins produced by the bacterium C. difficile, Toxin A (TcdA) and Toxin B (Tc …
·pubmed.ncbi.nlm.nih.gov·
Exploring the Toxin-Mediated Mechanisms in Clostridioides difficile Infection - PubMed
Toxin genotypes, antibiotic resistance and their correlations in Clostridioides difficile isolated from hospitals in Xi'an, China - PubMed
Toxin genotypes, antibiotic resistance and their correlations in Clostridioides difficile isolated from hospitals in Xi'an, China - PubMed
Currently, the prevalence rate of C. difficile infection (CDI) in Xi'an is 12.67% (156/1231), with the major toxin genotype of the isolates being tcdA + tcdB + cdtA-/B-. Metronidazole and vancomycin were still effective drugs for the treatment of CDI, but we should pay attention to antibiotic manage …
·pubmed.ncbi.nlm.nih.gov·
Toxin genotypes, antibiotic resistance and their correlations in Clostridioides difficile isolated from hospitals in Xi'an, China - PubMed
Functional characterization of Fur from the strict anaerobe Clostridioides difficile provides insight into its redox-driven regulatory capacity - PubMed
Functional characterization of Fur from the strict anaerobe Clostridioides difficile provides insight into its redox-driven regulatory capacity - PubMed
Clostridioides (formerly Clostridium) difficile is a leading cause of infectious diarrhea associated with antibiotic therapy. The ability of this anaerobic pathogen to acquire enough iron to proliferate under iron limitation conditions imposed by the host largely determines its pathogenicity. Howeve …
·pubmed.ncbi.nlm.nih.gov·
Functional characterization of Fur from the strict anaerobe Clostridioides difficile provides insight into its redox-driven regulatory capacity - PubMed
Gastrointestinal Conditions: Acute Infectious Gastroenteritis and Colitis - PubMed
Gastrointestinal Conditions: Acute Infectious Gastroenteritis and Colitis - PubMed
Gastroenteritis is inflammation of the stomach and intestines; colitis is inflammation of the colon. Viruses are the most common cause, followed by bacteria and parasites. Incidence of the various infections varies by age, sex, location, and vaccine availability; vaccination has reduced rotavirus in …
·pubmed.ncbi.nlm.nih.gov·
Gastrointestinal Conditions: Acute Infectious Gastroenteritis and Colitis - PubMed
Metagenome-assembled genomes (MAGs) suggest an acetate-driven protective role in gut microbiota disrupted by Clostridioides difficile - PubMed
Metagenome-assembled genomes (MAGs) suggest an acetate-driven protective role in gut microbiota disrupted by Clostridioides difficile - PubMed
Clostridioides difficile may have a negative impact on gut microbiota composition in terms of diversity and abundance, thereby triggering functional changes supported by the differential presence of genes involved in significant metabolic pathways, such as short-chain fatty acids (SCFA). This work h …
·pubmed.ncbi.nlm.nih.gov·
Metagenome-assembled genomes (MAGs) suggest an acetate-driven protective role in gut microbiota disrupted by Clostridioides difficile - PubMed
Protection against Clostridioides difficile disease by a naturally avirulent C. difficile strain - PubMed
Protection against Clostridioides difficile disease by a naturally avirulent C. difficile strain - PubMed
Clostridioides difficile infections (CDI) are prevalent in healthcare settings and are associated with high recurrence rates. Therapies to prevent CDI, including recent FDA-approved live biotherapeutic products, are costly and have not been used to prevent primary infections. While a nontoxig …
·pubmed.ncbi.nlm.nih.gov·
Protection against Clostridioides difficile disease by a naturally avirulent C. difficile strain - PubMed
Toxin genotypes, antibiotic resistance and their correlations in Clostridioides difficile isolated from hospitals in Xi'an, China - PubMed
Toxin genotypes, antibiotic resistance and their correlations in Clostridioides difficile isolated from hospitals in Xi'an, China - PubMed
Currently, the prevalence rate of C. difficile infection (CDI) in Xi'an is 12.67% (156/1231), with the major toxin genotype of the isolates being tcdA + tcdB + cdtA-/B-. Metronidazole and vancomycin were still effective drugs for the treatment of CDI, but we should pay attention to antibiotic manage …
·pubmed.ncbi.nlm.nih.gov·
Toxin genotypes, antibiotic resistance and their correlations in Clostridioides difficile isolated from hospitals in Xi'an, China - PubMed
Functional characterization of Fur from the strict anaerobe Clostridioides difficile provides insight into its redox-driven regulatory capacity - PubMed
Functional characterization of Fur from the strict anaerobe Clostridioides difficile provides insight into its redox-driven regulatory capacity - PubMed
Clostridioides (formerly Clostridium) difficile is a leading cause of infectious diarrhea associated with antibiotic therapy. The ability of this anaerobic pathogen to acquire enough iron to proliferate under iron limitation conditions imposed by the host largely determines its pathogenicity. Howeve …
·pubmed.ncbi.nlm.nih.gov·
Functional characterization of Fur from the strict anaerobe Clostridioides difficile provides insight into its redox-driven regulatory capacity - PubMed
Gastrointestinal Conditions: Acute Infectious Gastroenteritis and Colitis - PubMed
Gastrointestinal Conditions: Acute Infectious Gastroenteritis and Colitis - PubMed
Gastroenteritis is inflammation of the stomach and intestines; colitis is inflammation of the colon. Viruses are the most common cause, followed by bacteria and parasites. Incidence of the various infections varies by age, sex, location, and vaccine availability; vaccination has reduced rotavirus in …
·pubmed.ncbi.nlm.nih.gov·
Gastrointestinal Conditions: Acute Infectious Gastroenteritis and Colitis - PubMed
Progress on mechanisms of antibiotic resistance in Clostridioides difficile - PubMed
Progress on mechanisms of antibiotic resistance in Clostridioides difficile - PubMed
Clostridioides difficile (CD) is one of the most common pathogens causing health-care-associated infectious diarrhea and is listed by the U.S. Centers for Disease Control and Prevention as an urgent antibiotic resistance (AR) threat. Many resistance genes can be transferred between different CD stra …
·pubmed.ncbi.nlm.nih.gov·
Progress on mechanisms of antibiotic resistance in Clostridioides difficile - PubMed
Protection against Clostridioides difficile disease by a naturally avirulent C. difficile strain - PubMed
Protection against Clostridioides difficile disease by a naturally avirulent C. difficile strain - PubMed
Clostridioides difficile infections (CDI) are prevalent in healthcare settings and are associated with high recurrence rates. Therapies to prevent CDI, including recent FDA-approved live biotherapeutic products, are costly and have not been used to prevent primary infections. While a nontoxig …
·pubmed.ncbi.nlm.nih.gov·
Protection against Clostridioides difficile disease by a naturally avirulent C. difficile strain - PubMed
Metagenome-assembled genomes (MAGs) suggest an acetate-driven protective role in gut microbiota disrupted by Clostridioides difficile - PubMed
Metagenome-assembled genomes (MAGs) suggest an acetate-driven protective role in gut microbiota disrupted by Clostridioides difficile - PubMed
Clostridioides difficile may have a negative impact on gut microbiota composition in terms of diversity and abundance, thereby triggering functional changes supported by the differential presence of genes involved in significant metabolic pathways, such as short-chain fatty acids (SCFA). This work h …
·pubmed.ncbi.nlm.nih.gov·
Metagenome-assembled genomes (MAGs) suggest an acetate-driven protective role in gut microbiota disrupted by Clostridioides difficile - PubMed