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Correction: Dynamics of inflammation-associated plasma proteins following faecal microbiota transplantation in patients with psoriatic arthritis and healthy controls: exploratory findings from the FLORA trial - PubMed
Correction: Dynamics of inflammation-associated plasma proteins following faecal microbiota transplantation in patients with psoriatic arthritis and healthy controls: exploratory findings from the FLORA trial - PubMed
Correction: Dynamics of inflammation-associated plasma proteins following faecal microbiota transplantation in patients with psoriatic arthritis and healthy controls: exploratory findings from the FLORA trial
·pubmed.ncbi.nlm.nih.gov·
Correction: Dynamics of inflammation-associated plasma proteins following faecal microbiota transplantation in patients with psoriatic arthritis and healthy controls: exploratory findings from the FLORA trial - PubMed
Horizontal gene transfer after faecal microbiota transplantation in adolescents with obesity - PubMed
Horizontal gene transfer after faecal microbiota transplantation in adolescents with obesity - PubMed
Our study suggests that novel microorganisms introduced into the recipient gut following FMT have no impact on the basal rate of HGT within the human gut microbiome. Analyses of further FMT studies are required to assess the generalisability of this conclusion across different FMT study designs and …
·pubmed.ncbi.nlm.nih.gov·
Horizontal gene transfer after faecal microbiota transplantation in adolescents with obesity - PubMed
Heterogeneity in practices to reduce the risk of transmission of Clostridioides difficile in healthcare settings: a survey of ESCMID Study Group for Clostridioides difficile (ESGCD) members - PubMed
Heterogeneity in practices to reduce the risk of transmission of Clostridioides difficile in healthcare settings: a survey of ESCMID Study Group for Clostridioides difficile (ESGCD) members - PubMed
Clostridioides difficile is a leading cause of healthcare-associated infections. The main objective was to assess the current landscape of CDI infection prevention and control (IPC) practices. An anonymous survey of IPC practices for CDI was conducted between July 25 and October 31, 2022. Precaution …
·pubmed.ncbi.nlm.nih.gov·
Heterogeneity in practices to reduce the risk of transmission of Clostridioides difficile in healthcare settings: a survey of ESCMID Study Group for Clostridioides difficile (ESGCD) members - PubMed
Watery Diarrhea Is Not Always Clostridioides difficile: A Case Report of Aeromonas hydrophila Gastroenteritis - PubMed
Watery Diarrhea Is Not Always Clostridioides difficile: A Case Report of Aeromonas hydrophila Gastroenteritis - PubMed
Aeromonas species can cause acute gastroenteritis but are much less commonly observed in the hospital setting than other bacteria. Most cases of Aeromonas hydrophila gastroenteritis reported in the literature have occurred in pediatric, elderly, and/or immunocompromised patients. We pr …
·pubmed.ncbi.nlm.nih.gov·
Watery Diarrhea Is Not Always Clostridioides difficile: A Case Report of Aeromonas hydrophila Gastroenteritis - PubMed
Rethinking Clostridioides difficile infection (CDI) surveillance definitions based on changing healthcare utilisation and a more realistic incubation period: reviewing data from a tertiary-referral hospital, Ireland, 2012 to 2021 - PubMed
Rethinking Clostridioides difficile infection (CDI) surveillance definitions based on changing healthcare utilisation and a more realistic incubation period: reviewing data from a tertiary-referral hospital, Ireland, 2012 to 2021 - PubMed
BackgroundCommunity-associated Clostridioides difficile infections (CA-CDI) have increased worldwide. Patients with CDI-related symptoms occurring 48 hours after hospitalisation and no inpatient stay 12 weeks prior are classified as CA-CDI, regardless of hospital day attendances 3 months …
·pubmed.ncbi.nlm.nih.gov·
Rethinking Clostridioides difficile infection (CDI) surveillance definitions based on changing healthcare utilisation and a more realistic incubation period: reviewing data from a tertiary-referral hospital, Ireland, 2012 to 2021 - PubMed
Isofagomine Inhibits Multiple TcdB Variants and Protects Mice from Clostridioides difficile-Induced Mortality - PubMed
Isofagomine Inhibits Multiple TcdB Variants and Protects Mice from Clostridioides difficile-Induced Mortality - PubMed
Clostridioides difficile causes life-threatening diarrhea and is one of the leading causes of nosocomial infections. During infection, C. difficile releases two gut-damaging toxins, TcdA and TcdB, which are the primary determinants of disease pathogenesis and are important therapeutic …
·pubmed.ncbi.nlm.nih.gov·
Isofagomine Inhibits Multiple TcdB Variants and Protects Mice from Clostridioides difficile-Induced Mortality - PubMed
Culture-independent detection of low-abundant Clostridioides difficile in environmental DNA via PCR - PubMed
Culture-independent detection of low-abundant Clostridioides difficile in environmental DNA via PCR - PubMed
Clostridioides difficile represents a major burden to public health. As a well-known nosocomial pathogen whose occurrence is highly associated with antibiotic treatment, most examined C. difficile strains originated from clinical specimen and were isolated under selective conditions em …
·pubmed.ncbi.nlm.nih.gov·
Culture-independent detection of low-abundant Clostridioides difficile in environmental DNA via PCR - PubMed
Primary clostridium difficile infection in patients with ulcerative colitis: Case report and literature review - PubMed
Primary clostridium difficile infection in patients with ulcerative colitis: Case report and literature review - PubMed
We illustrate the potential effectiveness of this medication by presenting an in-depth case report of a patient with early-stage UC. The report outlines the patient inclusion of infliximab to better manage UC inflammation alongside an adjunct vancomycin regimen, given the ineffectiveness of mesalazi …
·pubmed.ncbi.nlm.nih.gov·
Primary clostridium difficile infection in patients with ulcerative colitis: Case report and literature review - PubMed
The burden of Clostridioides difficile infections in South-East Asia and the Western Pacific: A narrative review - PubMed
The burden of Clostridioides difficile infections in South-East Asia and the Western Pacific: A narrative review - PubMed
The regional CDI burden in Asia is still incompletely documented, seemingly due to low awareness and limited laboratory testing. Despite this apparent under recognition, the current CDI burden highlights the need for broader surveillance and for application of preventative measures against CDI in As …
·pubmed.ncbi.nlm.nih.gov·
The burden of Clostridioides difficile infections in South-East Asia and the Western Pacific: A narrative review - PubMed
Immunogenicity and safety in rabbits of a Clostridioides difficile vaccine combining novel toxoids and a novel adjuvant - PubMed
Immunogenicity and safety in rabbits of a Clostridioides difficile vaccine combining novel toxoids and a novel adjuvant - PubMed
Clostridioides difficile infection (CDI) is a serious healthcare-associated disease, causing symptoms such as diarrhea and pseudomembranous colitis. The major virulence factors responsible for the disease symptoms are two secreted cytotoxic proteins, TcdA and TcdB. A parenteral vaccine based on form …
·pubmed.ncbi.nlm.nih.gov·
Immunogenicity and safety in rabbits of a Clostridioides difficile vaccine combining novel toxoids and a novel adjuvant - PubMed
Many Hands, Light Work: A Partnership Approach to Reducing Clostridioides difficile Burden on an Oncology Unit - PubMed
Many Hands, Light Work: A Partnership Approach to Reducing Clostridioides difficile Burden on an Oncology Unit - PubMed
An increase in hospital-onset Clostridioides difficile (HO-CDI) prompted an interprofessional team to implement enhanced environmental service cleaning practices and adopt a routine cleaning program undertaken by clinical staff. These interventions resulted in a reduction of HO-CDI from 7.27 cases p …
·pubmed.ncbi.nlm.nih.gov·
Many Hands, Light Work: A Partnership Approach to Reducing Clostridioides difficile Burden on an Oncology Unit - PubMed
Microscopy methods for Clostridioides difficile - PubMed
Microscopy methods for Clostridioides difficile - PubMed
Microscopic technologies including light and fluorescent, transmission electron microscopy (TEM), scanning electron microscopy (SEM), and cryo-electron microscopy have been widely utilized to visualize Clostridioides difficile at the molecular, cellular, community, and structural biology level. This …
·pubmed.ncbi.nlm.nih.gov·
Microscopy methods for Clostridioides difficile - PubMed
Oral exposure of polystyrene microplastics and doxycycline affects mice neurological function via gut microbiota disruption: The orchestrating role of fecal microbiota transplantation - PubMed
Oral exposure of polystyrene microplastics and doxycycline affects mice neurological function via gut microbiota disruption: The orchestrating role of fecal microbiota transplantation - PubMed
The debris of plastics with a size 5 mm, called microplastics, possess long-lived legacies of plastic pollution and a growing threat to human beings. The adverse effects and corresponding molecular mechanisms of microplastics are still largely unknown and must be prioritized. Antibiotics common …
·pubmed.ncbi.nlm.nih.gov·
Oral exposure of polystyrene microplastics and doxycycline affects mice neurological function via gut microbiota disruption: The orchestrating role of fecal microbiota transplantation - PubMed
Sterile Fecal Microbiota Transplantation Boosts Anti-Inflammatory T-Cell Response in Ulcerative Colitis Patients - PubMed
Sterile Fecal Microbiota Transplantation Boosts Anti-Inflammatory T-Cell Response in Ulcerative Colitis Patients - PubMed
Ulcerative colitis is a chronic immune-mediated disease of unclear etiology, affecting people of different ages and significantly reducing the quality of life. Modern methods of therapy are mainly represented by anti-inflammatory drugs and are not aimed at a specific pathogenetic factor. In this stu …
·pubmed.ncbi.nlm.nih.gov·
Sterile Fecal Microbiota Transplantation Boosts Anti-Inflammatory T-Cell Response in Ulcerative Colitis Patients - PubMed
Current perspectives on fecal microbiota transplantation in inflammatory bowel disease - PubMed
Current perspectives on fecal microbiota transplantation in inflammatory bowel disease - PubMed
Fecal microbiota transplantation (FMT) has emerged as a promising therapeutic modality within the domain of inflammatory bowel disease (IBD). While FMT has secured approval and demonstrated efficacy in addressing recurrent and refractory Clostridioides difficile infection, its application in IBD rem …
·pubmed.ncbi.nlm.nih.gov·
Current perspectives on fecal microbiota transplantation in inflammatory bowel disease - PubMed
Intestinal bile acids provide a surmountable barrier against C. difficile TcdB-induced disease pathogenesis | Proceedings of the National Academy of Sciences
Intestinal bile acids provide a surmountable barrier against C. difficile TcdB-induced disease pathogenesis | Proceedings of the National Academy of Sciences
Intestinal bile acids play an essential role in the Clostridioides difficile lifecycle having been shown in vitro to modulate various aspects of pa...
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Intestinal bile acids provide a surmountable barrier against C. difficile TcdB-induced disease pathogenesis | Proceedings of the National Academy of Sciences
Multicenter evaluation of BioCode GPP for syndromic molecular detection of gastrointestinal pathogens from stool specimens - PubMed
Multicenter evaluation of BioCode GPP for syndromic molecular detection of gastrointestinal pathogens from stool specimens - PubMed
Acute gastroenteritis (AGE) is a leading cause of morbidity and mortality worldwide across all age groups that disproportionally affects young children in low- and middle-income countries and immunocompromised patients in high-income countries. Regional outbreaks of AGE are typically detected by tra …
·pubmed.ncbi.nlm.nih.gov·
Multicenter evaluation of BioCode GPP for syndromic molecular detection of gastrointestinal pathogens from stool specimens - PubMed
A rationally designed antimicrobial peptide from structural and functional insights of Clostridioides difficile translation initiation factor 1 - PubMed
A rationally designed antimicrobial peptide from structural and functional insights of Clostridioides difficile translation initiation factor 1 - PubMed
A significant increase of hospital-acquired bacterial infections during the COVID-19 pandemic has become an urgent medical problem. Clostridioides difficile is an urgent antibiotic-resistant bacterial pathogen and a leading causative agent of nosocomial infections. The increasing recurrence o …
·pubmed.ncbi.nlm.nih.gov·
A rationally designed antimicrobial peptide from structural and functional insights of Clostridioides difficile translation initiation factor 1 - PubMed
Genomic surveillance of Clostridioides difficile transmission and virulence in a healthcare setting - PubMed
Genomic surveillance of Clostridioides difficile transmission and virulence in a healthcare setting - PubMed
Clostridioides difficile infection (CDI) is a major cause of healthcare-associated diarrhea, despite the widespread implementation of contact precautions for patients with CDI. Here, we investigate strain contamination in a hospital setting and the genomic determinants of disease outcomes. Ac …
·pubmed.ncbi.nlm.nih.gov·
Genomic surveillance of Clostridioides difficile transmission and virulence in a healthcare setting - PubMed
The multiplicity of thioredoxin systems meets the specific lifestyles of Clostridia - PubMed
The multiplicity of thioredoxin systems meets the specific lifestyles of Clostridia - PubMed
Cells are unceasingly confronted by oxidative stresses that oxidize proteins on their cysteines. The thioredoxin (Trx) system, which is a ubiquitous system for thiol and protein repair, is composed of a thioredoxin (TrxA) and a thioredoxin reductase (TrxB). TrxAs reduce disulfide bonds of oxidized p …
·pubmed.ncbi.nlm.nih.gov·
The multiplicity of thioredoxin systems meets the specific lifestyles of Clostridia - PubMed
Re: 'The Effect of Antibiotic Therapy for Clostridioides difficile Infection on Mortality and Other Patient-Relevant Outcomes' by Stabholz et al - PubMed
Re: 'The Effect of Antibiotic Therapy for Clostridioides difficile Infection on Mortality and Other Patient-Relevant Outcomes' by Stabholz et al - PubMed
Re: 'The Effect of Antibiotic Therapy for Clostridioides difficile Infection on Mortality and Other Patient-Relevant Outcomes' by Stabholz et al
·pubmed.ncbi.nlm.nih.gov·
Re: 'The Effect of Antibiotic Therapy for Clostridioides difficile Infection on Mortality and Other Patient-Relevant Outcomes' by Stabholz et al - PubMed
Novel Drivers of Virulence in Clostridioides difficile Identified via Context-Specific Metabolic Network Analysis | mSystems
Novel Drivers of Virulence in Clostridioides difficile Identified via Context-Specific Metabolic Network Analysis | mSystems
Clostridioides difficile has become the leading single cause of hospital-acquired infections. Numerous studies have demonstrated the importance of specific metabolic pathways in aspects of C. difficile pathophysiology, from initial colonization to ...
·news.google.com·
Novel Drivers of Virulence in Clostridioides difficile Identified via Context-Specific Metabolic Network Analysis | mSystems
Fecal Microbiota Transplantation for Clostridium difficile-associated Diarrhea in Hematopoietic Stem Cell Transplant Recipients: A Single-center Experience from a Tertiary Center in India - PubMed
Fecal Microbiota Transplantation for Clostridium difficile-associated Diarrhea in Hematopoietic Stem Cell Transplant Recipients: A Single-center Experience from a Tertiary Center in India - PubMed
Prayag PS, Patwardhan SA, Ajapuje PS, Melinkeri S, Gadhikar H, Palnitkar S, et al. Fecal Microbiota Transplantation for Clostridium difficile-associated Diarrhea in Hematopoietic Stem Cell Transplant Recipients: A Single-center Experience from a Tertiary Center in India. Indian J Crit …
·pubmed.ncbi.nlm.nih.gov·
Fecal Microbiota Transplantation for Clostridium difficile-associated Diarrhea in Hematopoietic Stem Cell Transplant Recipients: A Single-center Experience from a Tertiary Center in India - PubMed
Gut microbiota and its therapeutic implications in tumor microenvironment interactions - PubMed
Gut microbiota and its therapeutic implications in tumor microenvironment interactions - PubMed
The development of cancer is not just the growth and proliferation of a single transformed cell, but its tumor microenvironment (TME) also coevolves with it, which is primarily involved in tumor initiation, development, metastasis, and therapeutic responses. Recent years, TME has been emerged as a p …
·pubmed.ncbi.nlm.nih.gov·
Gut microbiota and its therapeutic implications in tumor microenvironment interactions - PubMed