C Difficile

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Correlation between Alzheimer's Disease and Gastrointestinal Tract Disorders - PubMed
Correlation between Alzheimer's Disease and Gastrointestinal Tract Disorders - PubMed
Alzheimer's disease is the most common cause of dementia globally. The pathogenesis is multifactorial and includes deposition of amyloid-β in the central nervous system, presence of intraneuronal neurofibrillary tangles and a decreased amount of synapses. It remains uncertain what causes the progres …
·pubmed.ncbi.nlm.nih.gov·
Correlation between Alzheimer's Disease and Gastrointestinal Tract Disorders - PubMed
Ramulus Mori (Sangzhi) Alkaloids Alleviate Diabetic Nephropathy through Improving Gut Microbiota Disorder - PubMed
Ramulus Mori (Sangzhi) Alkaloids Alleviate Diabetic Nephropathy through Improving Gut Microbiota Disorder - PubMed
Diabetic nephropathy (DN), one of the leading causes of end-stage kidney failure worldwide, is closely associated with high mortality in diabetic patients. However, therapeutic drugs for DN are still lacking. Ramulus Mori alkaloids (SZ-A), an effective component of alkaloids extracted from …
·pubmed.ncbi.nlm.nih.gov·
Ramulus Mori (Sangzhi) Alkaloids Alleviate Diabetic Nephropathy through Improving Gut Microbiota Disorder - PubMed
The Contrasting Effects of Two Distinct Exercise Training Modalities on Exhaustive Exercise-Induced Muscle Damage in Mice May Be Associated with Alterations in the Gut Microbiota - PubMed
The Contrasting Effects of Two Distinct Exercise Training Modalities on Exhaustive Exercise-Induced Muscle Damage in Mice May Be Associated with Alterations in the Gut Microbiota - PubMed
Exhaustive exercise is known to induce muscle damage characterized by inflammation and oxidative stress. Although "regular" and "weekend warrior" exercise regimens have been shown to confer comparable health benefits in human studies, such as reduced risks of all-cause, cardiovascular disease (CVD), …
·pubmed.ncbi.nlm.nih.gov·
The Contrasting Effects of Two Distinct Exercise Training Modalities on Exhaustive Exercise-Induced Muscle Damage in Mice May Be Associated with Alterations in the Gut Microbiota - PubMed
Prospective Audit and Feedback for Antimicrobial Treatment of Patients Receiving Renal Replacement Therapy in Community-Based University Hospitals: A before-and-after Study - PubMed
Prospective Audit and Feedback for Antimicrobial Treatment of Patients Receiving Renal Replacement Therapy in Community-Based University Hospitals: A before-and-after Study - PubMed
In South Korea, because of manpower and budgetary limitations, antimicrobial stewardship programs have relied on preauthorization. This study analyzed the impact of a prospective audit and feedback (PAF) program targeting inpatients undergoing intermittent hemodialysis or continuous renal replacemen …
·pubmed.ncbi.nlm.nih.gov·
Prospective Audit and Feedback for Antimicrobial Treatment of Patients Receiving Renal Replacement Therapy in Community-Based University Hospitals: A before-and-after Study - PubMed
Comparative Efficacy of Fecal Microbiota Transplantation in Treating Refractory or Recurrent Clostridioides difficile Infection among Patients with and without Inflammatory Bowel Disease: A Retrospective Cohort Study - PubMed
Comparative Efficacy of Fecal Microbiota Transplantation in Treating Refractory or Recurrent Clostridioides difficile Infection among Patients with and without Inflammatory Bowel Disease: A Retrospective Cohort Study - PubMed
Clostridioides difficile infection (CDI) worsens inflammatory bowel disease (IBD) prognosis. While fecal microbiota transplantation (FMT) is effective for refractory or recurrent CDI (rrCDI), comparative success rates between IBD and non-IBD patients are scarce. This study addresses this gap. …
·pubmed.ncbi.nlm.nih.gov·
Comparative Efficacy of Fecal Microbiota Transplantation in Treating Refractory or Recurrent Clostridioides difficile Infection among Patients with and without Inflammatory Bowel Disease: A Retrospective Cohort Study - PubMed
Characterization of Clostridioides difficile Persister Cells and Their Role in Antibiotic Tolerance - PubMed
Characterization of Clostridioides difficile Persister Cells and Their Role in Antibiotic Tolerance - PubMed
Clostridioides difficile is a Gram-positive pathogen known for its toxin production and spore formation. It is primarily responsible for most cases of antibiotic-associated diarrhea. Bacterial persisters are a small subset of the population that exhibits transient tolerance to bactericidal su …
·pubmed.ncbi.nlm.nih.gov·
Characterization of Clostridioides difficile Persister Cells and Their Role in Antibiotic Tolerance - PubMed
Evaluation of Bacterial Viability for Fecal Microbiota Transplantation: Impact of Thawing Temperature and Storage Time - PubMed
Evaluation of Bacterial Viability for Fecal Microbiota Transplantation: Impact of Thawing Temperature and Storage Time - PubMed
Fecal Microbiota Transplantation (FMT) represents a promising therapeutic tool under study for several purposes and is currently applied to the treatment of recurrent Clostridioides difficile infection. However, since the use of fresh stool was affected by several issues linked to donor scree …
·pubmed.ncbi.nlm.nih.gov·
Evaluation of Bacterial Viability for Fecal Microbiota Transplantation: Impact of Thawing Temperature and Storage Time - PubMed
Clinical Characteristics and Risk Factors for Clostridioides difficile Infection in the Hematopoietic Cell Transplantation Population - PubMed
Clinical Characteristics and Risk Factors for Clostridioides difficile Infection in the Hematopoietic Cell Transplantation Population - PubMed
CDI presents an early complication after HCT, particularly in allogenic recipients who experience higher incidence rates and severe complications. Early recognition and management of these risk factors are essential to prevent these adverse outcomes.
·pubmed.ncbi.nlm.nih.gov·
Clinical Characteristics and Risk Factors for Clostridioides difficile Infection in the Hematopoietic Cell Transplantation Population - PubMed
Clostridioides difficile Infections: Prevention and Treatment Strategies - PubMed
Clostridioides difficile Infections: Prevention and Treatment Strategies - PubMed
Clostridioides difficile is the most common causative agent of antibiotic-associated diarrhea. This spore forming, obligate anaerobic, gram-positive bacillus is becoming responsible for an increasing number of infections worldwide, both in community and in hospital settings, whose severity can vary …
·pubmed.ncbi.nlm.nih.gov·
Clostridioides difficile Infections: Prevention and Treatment Strategies - PubMed
Clorox wipes receive EPA registration for C. diff
Clorox wipes receive EPA registration for C. diff
BALTIMORE — The Clorox Company has announced that the U.S. Environmental Protection Agency (EPA) accepted the registration of Clorox Commercial Solutions” Germicidal Wipes to kill Clostridium difficile (C. diff) spores in five minutes, according to a press release. The bleach wipe used by the most U.S. hospitals, Clorox Germicidal Wipes are ready-to-use, hospital-grade disinfectant wipes […]
·cmmonline.com·
Clorox wipes receive EPA registration for C. diff
Genomic study of European Clostridioides difficile ribotype 002/sequence type 8 - PubMed
Genomic study of European Clostridioides difficile ribotype 002/sequence type 8 - PubMed
Clostridioides difficile has significant clinical importance as a leading cause of healthcare-associated infections, with symptoms ranging from mild diarrhoea to severe colitis, and possible life-threatening complications. C. difficile ribotype (RT) 002, mainly associated with MLST seq …
·pubmed.ncbi.nlm.nih.gov·
Genomic study of European Clostridioides difficile ribotype 002/sequence type 8 - PubMed
Antimicrobial susceptibilities, resistance mechanisms and molecular characteristics of toxigenic Clostridioides difficile isolates in a large teaching hospital in Chongqing, China - PubMed
Antimicrobial susceptibilities, resistance mechanisms and molecular characteristics of toxigenic Clostridioides difficile isolates in a large teaching hospital in Chongqing, China - PubMed
In contrast to prior studies, we found higher proportions of ST3 isolates with decreased tigecycline sensitivity, sharing similar resistance patterns and resistance genes. In the resistance process of tigecycline and tetracycline, the tetA(P) and tetB(P) genes may play a weak role.
·pubmed.ncbi.nlm.nih.gov·
Antimicrobial susceptibilities, resistance mechanisms and molecular characteristics of toxigenic Clostridioides difficile isolates in a large teaching hospital in Chongqing, China - PubMed
Monoacylglycerol acyltransferase-2 inhibits colorectal carcinogenesis in APCmin+/- mice - PubMed
Monoacylglycerol acyltransferase-2 inhibits colorectal carcinogenesis in APCmin+/- mice - PubMed
Monoacylglycerol acyltransferase-2 (MOGAT2), encodes MOGAT enzyme in the re-synthesis of triacylglycerol and protects from metabolism disorders. While, its precise involvement in colorectal cancer (CRC) progression remains inadequately understood. Our study demonstrated that knockout of Mogat2 in Ap …
·pubmed.ncbi.nlm.nih.gov·
Monoacylglycerol acyltransferase-2 inhibits colorectal carcinogenesis in APCmin+/- mice - PubMed
Research Progress on Mechanisms of Modulating Gut Microbiota to Improve Symptoms of Major Depressive Disorder - PubMed
Research Progress on Mechanisms of Modulating Gut Microbiota to Improve Symptoms of Major Depressive Disorder - PubMed
Major depressive disorder (MDD) is a clinical condition that significantly impacts patients' physical and mental well-being, quality of life, and social functioning. The pathogenesis of MDD remains unclear, but accumulating evidence suggests a close relationship between gut microbiota and the occurr …
·pubmed.ncbi.nlm.nih.gov·
Research Progress on Mechanisms of Modulating Gut Microbiota to Improve Symptoms of Major Depressive Disorder - PubMed
The brain-protective mechanism of fecal microbiota transplantation from young donor mice in the natural aging process via exosome, gut microbiota, and metabolomics analyses - PubMed
The brain-protective mechanism of fecal microbiota transplantation from young donor mice in the natural aging process via exosome, gut microbiota, and metabolomics analyses - PubMed
The natural aging process is accompanied by changes in exosomes, gut microbiota, and metabolites. This study aimed to reveal the anti-aging effect and mechanisms of fecal microbiota transplantation (FMT) from young donors on the natural aging process in mice by analyzing exosomes, gut microbiota, an …
·pubmed.ncbi.nlm.nih.gov·
The brain-protective mechanism of fecal microbiota transplantation from young donor mice in the natural aging process via exosome, gut microbiota, and metabolomics analyses - PubMed
NAFLD/MASLD and the Gut-Liver Axis: From Pathogenesis to Treatment Options - PubMed
NAFLD/MASLD and the Gut-Liver Axis: From Pathogenesis to Treatment Options - PubMed
Nonalcoholic fatty liver disease (NAFLD) poses an emerging threat topublic health. Nonalcoholic steatohepatitis (NASH) is reported to be the most rapidly rising cause of hepatocellular carcinoma in the western world. Recently, a new term has been proposed: metabolic dysfunction-associated steatotic …
·pubmed.ncbi.nlm.nih.gov·
NAFLD/MASLD and the Gut-Liver Axis: From Pathogenesis to Treatment Options - PubMed
Fecal microbiota transplantation alleviates mild-moderate COVID-19 associated diarrhoea and depression symptoms: A prospective study of a randomized, double-blind clinical trial - PubMed
Fecal microbiota transplantation alleviates mild-moderate COVID-19 associated diarrhoea and depression symptoms: A prospective study of a randomized, double-blind clinical trial - PubMed
Currently, the emergence of the endemic Coronavirus disease (COVID-19) situation still poses a serious threat to public health. However, it remains elusive about the role of fecal microbiota transplantation in treating COVID-19. We performed a randomized, double-blind, placebo-controlled clinical tr …
·pubmed.ncbi.nlm.nih.gov·
Fecal microbiota transplantation alleviates mild-moderate COVID-19 associated diarrhoea and depression symptoms: A prospective study of a randomized, double-blind clinical trial - PubMed
More than a new name: Updates in the management of Clostridioides difficile infection - PubMed
More than a new name: Updates in the management of Clostridioides difficile infection - PubMed
Infections from Clostridioides difficile (often called C. diff) have long presented challenges for both patients and clinicians. Traditionally, C. diff has been considered a nosocomial infection, but in recent years, a noticeable spike in community-acquired cases has occurred. C. diff infection (CDI …
·pubmed.ncbi.nlm.nih.gov·
More than a new name: Updates in the management of Clostridioides difficile infection - PubMed
Antimicrobial susceptibilities, resistance mechanisms and molecular characteristics of toxigenic Clostridioides difficile isolates in a large teaching hospital in Chongqing, China - PubMed
Antimicrobial susceptibilities, resistance mechanisms and molecular characteristics of toxigenic Clostridioides difficile isolates in a large teaching hospital in Chongqing, China - PubMed
In contrast to prior studies, we found higher proportions of ST3 isolates with decreased tigecycline sensitivity, sharing similar resistance patterns and resistance genes. In the resistance process of tigecycline and tetracycline, the tetA(P) and tetB(P) genes may play a weak role.
·pubmed.ncbi.nlm.nih.gov·
Antimicrobial susceptibilities, resistance mechanisms and molecular characteristics of toxigenic Clostridioides difficile isolates in a large teaching hospital in Chongqing, China - PubMed
Impact of intravenous antibiotics for unconfirmed pulmonary infections in patients with acute decompensated heart failure at a community health system - PubMed
Impact of intravenous antibiotics for unconfirmed pulmonary infections in patients with acute decompensated heart failure at a community health system - PubMed
Use of IV antibiotics in patients with ADHF was associated with longer hospital length of stay and should be avoided in patients without evidence of infection.
·pubmed.ncbi.nlm.nih.gov·
Impact of intravenous antibiotics for unconfirmed pulmonary infections in patients with acute decompensated heart failure at a community health system - PubMed
Escape Velocity-the Launch of Microbiome Therapies - PubMed
Escape Velocity-the Launch of Microbiome Therapies - PubMed
Food and Drug Administration approval of the first microbiome therapies represents a true expansion the treatment paradigm for Clostridioides difficile but raises new questions about the future role of fecal microbiota transplantation. The authors outline the advances in microbiome therapeutic devel …
·pubmed.ncbi.nlm.nih.gov·
Escape Velocity-the Launch of Microbiome Therapies - PubMed
Genomic study of European Clostridioides difficile ribotype 002/sequence type 8 - PubMed
Genomic study of European Clostridioides difficile ribotype 002/sequence type 8 - PubMed
Clostridioides difficile has significant clinical importance as a leading cause of healthcare-associated infections, with symptoms ranging from mild diarrhoea to severe colitis, and possible life-threatening complications. C. difficile ribotype (RT) 002, mainly associated with MLST seq …
·pubmed.ncbi.nlm.nih.gov·
Genomic study of European Clostridioides difficile ribotype 002/sequence type 8 - PubMed
Impact of an Intervention Program on Clostridioides difficile Infections: Comparison of 2 Hospital Cohorts - PubMed
Impact of an Intervention Program on Clostridioides difficile Infections: Comparison of 2 Hospital Cohorts - PubMed
Implementation of a CDI intervention program based on recommendations from IDSs and improved access to specialized care during the follow-up is associated with enhanced quality of CDI management and potential reductions in hospital resource utilization.
·pubmed.ncbi.nlm.nih.gov·
Impact of an Intervention Program on Clostridioides difficile Infections: Comparison of 2 Hospital Cohorts - PubMed
Alcohol in Baijiu Contributes to the Increased Probability of Host Infection by Clostridioides difficile Spores - PubMed
Alcohol in Baijiu Contributes to the Increased Probability of Host Infection by Clostridioides difficile Spores - PubMed
Clostridioides difficile and its endospores possess the characteristics of a foodborne pathogen and have been detected at several stages in the food chain. In the presence of an imbalance in host intestinal ecology, C. difficile can proliferate and cause intestinal infections. Multiple …
·pubmed.ncbi.nlm.nih.gov·
Alcohol in Baijiu Contributes to the Increased Probability of Host Infection by Clostridioides difficile Spores - PubMed