C Difficile

9590 bookmarks
Newest
Role of the Alteration in Calcium Homeostasis in Cell Death Induced by Clostridioides difficile Toxin A and Toxin B - PubMed
Role of the Alteration in Calcium Homeostasis in Cell Death Induced by Clostridioides difficile Toxin A and Toxin B - PubMed
Clostridioides difficile (C. difficile), responsible for 15-25% of gastrointestinal infections, causes health problems mainly due to the toxic activity of toxins A and B (Tcds). These are responsible for its clinical manifestations, including diarrhea, pseudomembranous colitis, toxic m …
·pubmed.ncbi.nlm.nih.gov·
Role of the Alteration in Calcium Homeostasis in Cell Death Induced by Clostridioides difficile Toxin A and Toxin B - PubMed
Design of 8-mer peptides that block Clostridioides difficile toxin A in intestinal cells - PubMed
Design of 8-mer peptides that block Clostridioides difficile toxin A in intestinal cells - PubMed
Infections by Clostridioides difficile, a bacterium that targets the large intestine (colon), impact a large number of people worldwide. Bacterial colonization is mediated by two exotoxins: toxins A and B. Short peptides that can be delivered to the gut and inhibit the biocatalytic activity of these …
·pubmed.ncbi.nlm.nih.gov·
Design of 8-mer peptides that block Clostridioides difficile toxin A in intestinal cells - PubMed
GutMicrobiota Health on X
GutMicrobiota Health on X
In Germany, FMT is used less frequently than in the European comparison. One application hurdle is the regulatory classification of FMT as a non-approved drug, which leads to higher costs in manufacturing and makes reimbursement difficult: https://t.co/FmPHWbFkI3
·twitter.com·
GutMicrobiota Health on X
Role of probiotics in preventing Clostridioides difficile infection in older adults: an integrative review - PubMed
Role of probiotics in preventing Clostridioides difficile infection in older adults: an integrative review - PubMed
Clostridioides difficile infection (CDI) is the leading cause of healthcare-associated diarrhea. This infection can particularly affect older adults, the most susceptible to CDI. Currently, the standard therapeutic measure is antibiotic therapy, which in turn increases the risk of recurrence …
·pubmed.ncbi.nlm.nih.gov·
Role of probiotics in preventing Clostridioides difficile infection in older adults: an integrative review - PubMed
Living With C diff: A Trauma That Lingers
Living With C diff: A Trauma That Lingers
This is the first in an occasional series with members of the Peggy Lillis Foundation. Here is an opportunity to hear about people’s experiences, lessons learned, and the new treatments that can lead to hope and not the hopelessness people have been living with during their ordeals.
·contagionlive.com·
Living With C diff: A Trauma That Lingers
Next Steps in Ambulatory Stewardship - PubMed
Next Steps in Ambulatory Stewardship - PubMed
Most antibiotics are prescribed in ambulatory setting and at least 30% to 50% of these prescriptions are unnecessary. The use of antibiotics when not needed promotes the development of antibiotic resistant organisms and harms patients by placing them at risk for adverse drug events and Clostridioide …
·pubmed.ncbi.nlm.nih.gov·
Next Steps in Ambulatory Stewardship - PubMed
Gut microbiome on immune checkpoint inhibitor therapy and consequent immune-related colitis: a review - PubMed
Gut microbiome on immune checkpoint inhibitor therapy and consequent immune-related colitis: a review - PubMed
Immune checkpoint inhibitors have dramatically revolutionized the therapeutic landscape for patients with advanced malignancies. Recently, convincing evidence has shown meaningful influence of gut microbiome on human immune system. With the complex link between gut microbiome, host immunity and canc …
·pubmed.ncbi.nlm.nih.gov·
Gut microbiome on immune checkpoint inhibitor therapy and consequent immune-related colitis: a review - PubMed
Efficacy of washed microbiota transplantation for therapeutic targets of refractory functional constipation and the influencing factors: a single-center, retrospective, 24-week follow-up study - PubMed
Efficacy of washed microbiota transplantation for therapeutic targets of refractory functional constipation and the influencing factors: a single-center, retrospective, 24-week follow-up study - PubMed
WMT is efficacious in improving refractory FC-related therapeutic targets. The effectiveness of WMT in the management of FC is enhanced with the administration of multiple courses.
·pubmed.ncbi.nlm.nih.gov·
Efficacy of washed microbiota transplantation for therapeutic targets of refractory functional constipation and the influencing factors: a single-center, retrospective, 24-week follow-up study - PubMed
Absence of Toll-like Receptor 7 Ameliorates Survival and Reduces Intestinal Injury in Mice after Clostridium difficile Infection - PubMed
Absence of Toll-like Receptor 7 Ameliorates Survival and Reduces Intestinal Injury in Mice after Clostridium difficile Infection - PubMed
Clostridioides difficile (CD) is a major cause of antibiotic-associated diarrhea and pseudomembranous enteritis. C. difficile infection (CDI) is increasingly present in the community and represents a significant burden on the healthcare system. Identification of novel immune-based therapeutic target …
·pubmed.ncbi.nlm.nih.gov·
Absence of Toll-like Receptor 7 Ameliorates Survival and Reduces Intestinal Injury in Mice after Clostridium difficile Infection - PubMed
Design, Synthesis and Biological Evaluation of Novel PEG-Rakicidin B1 Hybrid as Clostridium difficile (CD) Targeted Anti-Bacterial Agent - PubMed
Design, Synthesis and Biological Evaluation of Novel PEG-Rakicidin B1 Hybrid as Clostridium difficile (CD) Targeted Anti-Bacterial Agent - PubMed
Rakicidin B1 was isolated and purified from the culture broth of a marine Streptomyces sp. as a potent anti-cancer agent, and lately the compound and its derivatives have firstly been found to possess anti-Clostridium difficile (CD) activity but with high cytotoxicity. Herein, followin …
·pubmed.ncbi.nlm.nih.gov·
Design, Synthesis and Biological Evaluation of Novel PEG-Rakicidin B1 Hybrid as Clostridium difficile (CD) Targeted Anti-Bacterial Agent - PubMed
Role of probiotics in preventing Clostridioides difficile infection in older adults: an integrative review - PubMed
Role of probiotics in preventing Clostridioides difficile infection in older adults: an integrative review - PubMed
Clostridioides difficile infection (CDI) is the leading cause of healthcare-associated diarrhea. This infection can particularly affect older adults, the most susceptible to CDI. Currently, the standard therapeutic measure is antibiotic therapy, which in turn increases the risk of recurrence …
·pubmed.ncbi.nlm.nih.gov·
Role of probiotics in preventing Clostridioides difficile infection in older adults: an integrative review - PubMed
Is Dysbiotic Gut the Cause of Low Back Pain? - PubMed
Is Dysbiotic Gut the Cause of Low Back Pain? - PubMed
Low back pain (LBP) is the foremost cause of disability that affects the day-to-day activities of millions of people worldwide. The putative trigger of LBP is linked to the gut microbiome (GM) and its dysbiotic environment. With the concept of GM, various disease pathogenesis has been revisited with …
·pubmed.ncbi.nlm.nih.gov·
Is Dysbiotic Gut the Cause of Low Back Pain? - PubMed
Dual RNA-seq identifies genes and pathways modulated during Clostridioides difficile colonization - PubMed
Dual RNA-seq identifies genes and pathways modulated during Clostridioides difficile colonization - PubMed
The gastrointestinal pathogen Clostridioides difficile is the most common cause of hospital-acquired diarrhea. Bacterial interactions with the gut mucosa are crucial for the establishment of C. difficile infection; however, key infection events like bacterial attachment and gut penetra …
·pubmed.ncbi.nlm.nih.gov·
Dual RNA-seq identifies genes and pathways modulated during Clostridioides difficile colonization - PubMed
Microbes for the mind
Microbes for the mind
Editor's note: This story originally appeared in the fall 2023 issue of ASU Thrive magazine.A new treatment from ASU is helping people with autism and children with a rare disorder called
·news.google.com·
Microbes for the mind
Mandatory MRSA, MSSA and Gram-negative bacteraemia and C. difficile infection: financial year April 2023 to March 2024
Mandatory MRSA, MSSA and Gram-negative bacteraemia and C. difficile infection: financial year April 2023 to March 2024
Mandatory surveillance of healthcare associated infections (HCAI); MRSA, MSSA and Gram-negative bacteraemia (Escherichia coli (E. coli), Pseudomonas aeruginosa (P. aeruginosa), Klebsiella species (Klebsiella. spp.), and Clostridioides difficile (C. difficile) infection. Annual data and epidemiological commentary for the financial year April 2023 to March 2024.
·news.google.com·
Mandatory MRSA, MSSA and Gram-negative bacteraemia and C. difficile infection: financial year April 2023 to March 2024
Surveillance of MRSA, MSSA and Gram-negative bacteraemia and C. difficile infection among Independent Sector providers: experimental statistics, April 2023 to March 2024
Surveillance of MRSA, MSSA and Gram-negative bacteraemia and C. difficile infection among Independent Sector providers: experimental statistics, April 2023 to March 2024
Counts and rates of MRSA, MSSA, E. coli, P. aeruginosa, Klebsiella spp. bacteraemia and C. difficile infection reported by independent sector healthcare organisations, with accompanying commentary.
·news.google.com·
Surveillance of MRSA, MSSA and Gram-negative bacteraemia and C. difficile infection among Independent Sector providers: experimental statistics, April 2023 to March 2024
Clostridioides difficile Infections among Pediatric Patients Hospitalized at an Oncology Department of a Tertiary Hospital in Poland - PubMed
Clostridioides difficile Infections among Pediatric Patients Hospitalized at an Oncology Department of a Tertiary Hospital in Poland - PubMed
Background and Objectives: Gastrointestinal tract infections caused by Clostridioides difficile bacteria are diagnosed in pediatric patients with increasing frequency. Children treated at pediatric units are a group of patients at high risk of this infection; therefore, appropriate dif …
·pubmed.ncbi.nlm.nih.gov·
Clostridioides difficile Infections among Pediatric Patients Hospitalized at an Oncology Department of a Tertiary Hospital in Poland - PubMed