H5N1 Flu

H5N1 bird flu infection in humans? After vets infected without symptoms, alarming new evidence suggests it is more common than we thought!

For scientist Dr. Richard Webby, the biggest ‘uh-oh’ moment was when the virus infected cows

It’s clear there’s no reason for optimism that H5N1 will fade away as a minor nuisance. To the contrary, the situation has only been trending worse.

Valid as of February 19, 2025: The National Advisory Committee on Immunization's rapid response related to preliminary guidance on human vaccination against avian influenza in a non-pandemic context as of December 2024.

(1) Background: The emergence of H5N1 Influenza A viruses clade 2.3.3.4b since 2020, have caused the mortality of thousands of birds/mammals worldwide, through evolu-tionary changes have been associated with acquired mutations and posttranslational modifications. (2) Methods: This study aimed to compare the mutational profile of H5N1 avian Influenza virus isolated from a Peruvian natural reserve, with recent data from other related international studies made in human and different species of domestic and wild birds and mammals. Briefly, the near complete protein sequences of Influenza virus coming from a Calidris alba were analyzed in a multisegmented level, altogether with 55 samples collected between 2022-2024 in different countries. Moreover, the glycosylation patterns were also predicted in silico. (3) Results: A total of 603 amino acid changes were found among H5N1 viruses analyzed, underscoring the detection of critical mutations HA:143T, HA:156A, HA:208K, NA: 71S, NP:52H, PA:336M, PA:36T, PA:85A/N, PB1-F2:66S, PB2:199S, PB2:292V, PB2:559T, as well as PA:86I, PA:432I, PA:558L, HA:492D, NA:70D, NS1-83P, PB1:515A, PA-X:57Q, PB1-F2:22E, NS1-21Q, NEP:67G, among others, considered of importance under One Health perspective. Similarly, changes in the N-linked glycosylation sites (NLGs) predicted in both HA and NA proteins were found, highlighting the loss/acquisition or changes in some NLGs sites such as 209NNTN, 100 NPTT, 302NSSM (HA) and 70NNTN, 68NISS, 50NGSV (NA). (4) Conclu-sions: This study provides our understanding about the evolution of current Influenza A viruses H5N1 HPAIV circulating globally. These findings outline the importance of sur-veillance updating mutational profiles and glycosylation patterns of these highly evolved virus.

UBC scientists have received new research funding to advance preparedness and response to avian influenza.

Immunology researchers find H5N1 ab treatment effective in monkeys.

Wisconsin veterinarian outlines the damage bird flu has wrought on the dairy industry over the past 11 months.

/PRNewswire/ -- Pretorian Labs, LLC. is one of the first laboratories in the US to test human patients for H5N1 virus (Bird Flu). This test is now available to...

Genome BC is funding a set of research projects to address the risk associated with a strain of avian influenza, of the H5N1 subtype. The BCCDC is conducting...

Field studies led by Wageningen University have demonstrated the efficacy of two vaccines in reducing mortality in poultry infected with the Highly Pathogenic Avian Influenza (HPAI) H1N1 virus, although it is too early to draw accurate conclusions about transmission.

Federal agriculture workers laid off in "Valentine's Day Massacre" deny they were part of a bloated bureaucracy.

Deaths of millions of laying hens are causing grocery stores to ration supplies and restaurants to raise prices for egg dishes.

The latest developments in avian influenza A (H5N1) surveillance for horses in the United States.

The Trump administration plans to roll out a new strategy against the bird flu. There are few details, but to bring egg prices down, the plan is aimed at trying to minimize the slaughter of chickens when the flu strikes a flock. More than 150 million poultry have been affected since 2022 and 58 people have been sickened by it. Geoff Bennett discussed more with epidemiologist Dr. Katelyn Jetelina.

Cross-reactive αβ T cell receptors (TCRs) recognizing multiple peptide variants can provide effective control of rapidly evolving viruses yet remain understudied. By screening 12 naturally occurring influenza-derived HLA-B*35:01-restricted nucleoprotein (NP)sub418-426/sub epitopes (B*35:01-NP …

We report the detection of a clade 2.3.4.4b A(H5N1) reassortant virus with a neuraminidase surface protein derived from a North American lineage low-pathogenic avian influenza virus. This virus caused a widespread and ongoing outbreak across 45 poultry farms in British Columbia, Canada. Isolates fro …

Updates on "bird flu" in cats, monkeys, and veterinarians

Nuclear safety workers faced a similar experience in recent days.

The CDC has confirmed 68 cases among people in the U.S. since March of last year.

The cuts come as the virus is wreaking havoc on poultry farms and raising egg prices in the US.

Agency works to rehire employees shortly after touting plan to ‘optimize workforce’ by cutting staff with help of Musk

ANALYSIS: The firing of bird flu experts while Trump’s team boasted about the federal response to the crisis was a misleading self-own by the White House

Canada's public health agency says this comes as a protective measure as bird flu cases, which can potentially spread between people, continue to rise.

Beginning the week of February 24, the Minnesota Department of Agriculture (MDA), working with state government and indust

USDA acknowledged the wrongful termination of staff involved in the H5N1 outbreak response and is moving to reinstate them.