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This study aimed to explore the mechanism of fucoidan in chronic kidney disease (CKD)-triggered cognitive dysfunction. The adenine-induced ICR strain CKD mice model was applied, and RNA-Seq was performed for differential gene analysis between aged-CKD and normal mice. As a result, fucoidan (100 and 200 mg kg−1) significantly reversed adenine-induced high expression of urea, uric acid in urine, and creatinine in serum, as well as the novel object recognition memory and spatial memory deficits. RNA sequencing analysis indicated that oxidative and inflammatory signaling were involved in adenine-induced kidney injury and cognitive dysfunction; furthermore, fucoidan inhibited oxidative stress via GSK3β-Nrf2-HO-1 signaling and ameliorated inflammatory response through regulation of microglia/macrophage polarization in the kidney and hippocampus of CKD mice. Additionally, we clarified six hallmarks in the hippocampus and four in the kidney, which were correlated with CKD-triggered cognitive dysfunction. This study provides a theoretical basis for the application of fucoidan in the treatment of CKD-triggered memory deficits.

What does historical research reveal about the Shroud of Turin? What have been the results of scientific testing? Is the Shroud a fraud, or could it possibly be the burial shroud of Jesus of Nazareth? We’ll explore these questions and more with Shroud researcher John Long on today's episode of Digging for Truth. Suggested articles for further reading: https://biblearchaeology.org/research/topics/the-shroud-of-turin

(NaturalHealth365) Oregon lawmakers accuse the CDC and FDA of statistical manipulation of COVID-19 data and demand grand jury investigation.

We have a so-called “expert” doctor who advocates for a treatment that is known to kill and is not effective against the Covid virus.

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(NaturalHealth365) Recent study finds alpha-lipoic acid promotes metabolic health and thereby guards against various chronic diseases.

As you can tell, Russ Breault has quite a different perspective on the mysterious linen cloth that has puzzled scholars and scientists for centuries. In Russ’s mind, it’s not an object or a graven image to be worshipped. Instead, Russ likes to call it, “The Receipt Of The Resurrection.” He said it well … Bought, purchased, redeemed and ransomed. And wouldn’t it be just like Jesus to leave behind undeniable proof of his resurrection that can’t be duplicated, copied or imitated by any man today? GET THE SHROUD OF TURIN PACKAGE: https://prophecywatchers.com/product/the-russ-breault-shroud-of-turin-package-by-russ-breault-free-shipping-in-the-usa/ We’re the Prophecy Watchers. We have a long history of working to bring the truth of Bible prophecy to an audience of Christian believers who may not have local access to sound prophetic teaching, based upon the inspired writings of the Apostles and the traditional doctrine concerning the rapture of the church. Though we don’t believe in setting dates, it is clear that the rapture of the church is imminent, perhaps much nearer than we think. DONATE: https://prophecywatchers.com/product/custom-donation-amount/ FIND US ON THE WEB: http://www.prophecywatchers.com FOLLOW US ON FACEBOOK: http://facebook.com/prophecywatchers DOWNLOAD OUR APP: https://subsplash.com/prophecywatchers/app

(NaturalHealth365) Recently released emails reveal that NIH secretly deleted information related to the genetic sequencing of SARS-CoV-2.

NutriGenetic Research Institute is committed to studying the relationship between environmental and other epigenetic factors and individual’s genetics to better understand the role genetics may play in patient wellness.

Recently, fucoidan has been proposed for use as a potential anti-inflammatory drug. The purpose of this study was to investigate the mechanism of fucoidan in the treatment of ulcerative colitis. We compared the anti-inflammatory effects of fucoidan and fucose induced by dextran sulfate sodium, and the effects of fucoidan and fucose on the gut microbiota of mice. Our results showed that low-dose fucoidan significantly improved weight loss, disease activity index scores, colonic shortening, colonic histopathological damage, intestinal fatty acid binding protein 2 levels, and the expression of Occludin, Claudin-4, and Claudin-1. However, both high-dose fucoidan and fucose did not perform as well as low-dose fucoidan as described above. In addition, 16S rDNA high-throughput sequencing showed that low-dose fucoidan significantly increased the abundance of Alloprevotella, and fucose significantly increased Ruminococcaceae, but neither significantly reversed the imbalance in the gut microbiota. Therefore, we inferred that the regulation of fucoidan on colitis has a unique and complex mechanism, and it is not completely dependent on degradation to fucose to relieve ulcerative colitis, nor is it achieved only by regulating the gut microbiota. The mechanism by which fucoidan treats colitis may also include reducing inflammatory cell infiltration and increasing intestinal barrier function.

Over the years, we have emphasized the importance of physical exercise as it relates to Alzheimer’s risk and even progression.

Coronary Calcium Score Benefits of Aged Garlic

Anyone with a medical brain knows that doctors never dream of curing diabetes. That is too bad, and as a result, people with diabetes suffer significantly. However, type two diabetes is curable if you ignore your doctor’s advice. Diabetes is not the hopeless disease that most doctors would have us believe it is. It is only futile... View Article

(NaturalHealth365) Doctor reports alarming number of hospitalized patients with COVID jab-induced autoimmune deficiency syndrome.

(NaturalHealth365) Study results contradict the effectiveness of COVID shots, question the validity and legitimacy of vax mandates.

In early 2020 Dr. Ardis lost his Father-in-law because of ill-advised hospital protocols. Since that time, he has been on a mission to help educate the public about the dangers in many of our "institutes of health". . Download the video: http…

Check out our partner for this episode www.Finestknown.com/swann Emails from Hunter Biden's laptop confirm that he not only invested $500,000 into a bio-lab company based in Ukraine, but raised nearly $30 million dollars for that lab and secured U.S. Department of Defense contracts while his father was Vice President of the United States. Part 1

Check out our partner for this episode https://www.createtailwind.com In Part 2 of our report on Hunter Biden's ties to the Ukrainian Bio-Labs, we explain that Metabiota, the lab in which Biden invested and raised millions of dollars, is tied to Eco-health Alliance and the Wuhan Institute of Virology, the two entities that appear to have created covid-19 through gain-of-function research.

In this interview, Dr. Wright, the pioneer of D-Mannose and SSKI For UTI Treatment, suggests his protocol for UTI treatment and prevention with these natural, non-antibiotic solutions. Dr. Wright also shares his thoughts on UTI-prevention diet, and UTI risk factors (such as allergies and hormonal imbalance).

In this powerful interview, you will meet Dr. Henry Ealy, one of the most courageous, principled, and productive humanitarians of our time, who has gathered together some of the world's finest researchers to expose the CDC's COVID data manipulation and overinflation, which translated into the government's draconian COVID policies.Don't forget to check out the following links mentioned in this important interview (which we encourage you to share widely):1) Breaking News: Oregon legislators file for a Federal Grand Jury Investigation2) COVID-19 Data Collection, Comorbidity & Federal Law: A Historical Retrospective 3) The Problems With PCR Testing Why Public Officials Shouldn’t Base Restrictions On PCR Tests4) COVID-19: Restoring Public Trust During A Global Health Crisis5) Register for COVID CON 2021Don't forget to register for COVID CONFERENCE 2021, STARTING OCTOBER 14TH HERE. Get free access for the kick off day! You are invited to attend an exciting in-person and online event, the COVID CON ‘21 SOLUTION SUMMIT, kicking off October 14th, 15th & 16th from the Church of Glad Tidings in Live Oak, California!⠀✅ Claim Your Free Special Guest Pass at the LINK below for the first day of the conference & get 10% off for the rest of the weekend, using Promo Code: GMI.⠀What’s also fantastic about this community-building, solution-centered gathering is that all proceeds go directly towards funding unbiased science, public education and expert legal action coordinated to fight for and protect your freedom!⠀The good news is that the COVID CON ‘21 team has also created a growing list of FREE and amazingly useful resources to support you and your family available at the link HERE.

Urinary tract infections are some of the most frequent clinical bacterial infections in women, accounting for nearly 25 percent of all infections.

About 50 percent of women worldwide experience a urinary tract infection at some point in their lives. While many are prescribed antibiotics, there is a growing...

Dr Gundry's New Book: https://amzn.to/3iM5gpH In this episode, Dr. Steven Gundry joins Dr. Jockers to unlock the code that can add 10 more years into the lifespan and health span of man. They will challenge a few paradoxes that are proven to trigger leaky gut and damage the mitochondria in more ways than we can imagine. Learn how to boost the production of the #1 miraculous fuel in the body – which enables the mitochondria to save themselves and to make more – and why this is vital. Time stamps below! Today’s episode is proudly sponsored by Paleovalley and its 100% grass-fed beef and 100% pasture-raised turkey meat sticks, one of the choice snacks in my household. Hurry and grab yours from Paleovalley.com and be sure to use code JOCKERS at checkout for an extra 15% off! This episode is also proudly sponsored by C60PurplePower.com. Carbon 60 (C60) is a recently discovered, Nobel Prize-winning, super anti-oxidant that supports a healthy inflammatory response, promotes healthy immune function, and increases energy and mental clarity in most users. C60 Purple Power is the “Swiss Army Knife” of antioxidants because it helps the body replace four critical antioxidants that decrease as we age. If you are interested in healthy aging – you MUST check out C60 Purple Power! Use code DRJOCKERS for 15% OFF at https://c60purplepower.com/jockers. In This Episode: 00:00 - In this episode, Dr. Jocker's discusses Leaky Gut, Mitochondria, and Unlocking the Keto Code with Dr. Steven Gundry. 01:05 - Let’s decode the plant paradox. We’ll pick out the specific parts of plants that can lead to a leaky gut and seriously threaten your immune system. 04:32 - Meet the 7 deadly disruptors of the gut microbiome that prove Hippocrates’ wise claim that “all disease begins in the gut. 05:45 - Identify the BIGGEST troublemaker of all time. Just by eating it (or the animals that consume it), we kill off the tropical rainforest in our gut. 25:10 - Find out the many reasons why Dr. Gundry is an avid fan of polyphenols and why we should be too. 27:58 - Discover the sole determining factor of how long and how well we’re gonna live. Even if you just tune in for this, it will be worth it! 41:24 - Dr. Gundry breaks down the energy paradox and how intermittent fasting mobilizes your mitochondria while kicking your ketones into action. 46:30 - Dr. Gundry teaches the trick to reach the goals you really want: burn free fatty acids, lower insulin, and achieve the ketone effect. BONUS TIP: Learn how to make the BEST ketogenic uncoupling food in the world! Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging by Cynthia Thurlow - https://amzn.to/3LniBSt Apple Podcast - https://podcasts.apple.com/us/podcast/dr-jockers-functional-nutrition/id1497791107 Spotify - https://open.spotify.com/show/5l0LkYqW29ksV9Ut3hPuto