2016

Rough notes from the webinar The Scientist: Precision Medicine Learning Lessons from the Microbiome (now available online)

Bile acids, which are altered by bacteria normally living in the large intestine, inhibit the growth of Clostridium difficile, new research indicates. The work sheds light on the ways in which some commonly used antibiotics can promote C. diff infections by killing off the bile acid-altering microbes.

Learn more about this infectious disease that is becoming more common and often affects older adults in a health care facility, often after antibiotic use.

Abstract. In a case–control study of patients with Clostridium difficile infection, we found no statistically significant association between the presence of tr

CHD-FA was well tolerated, with no difference in reported side effects other than a short-lived burning sensation on application. CHD-FA significantly improved some aspects of eczema. Investigator assessment of global response to treatment with CHD-FA was significantly better than that with emollien …

This study assessed the effect of dissolved organic matter on the copper (Cu) bioavailability to mammalian cells, porcine oviductal epithelial cells (POEC), in order to imply its effect onto humans. Cu toxicity was investigated in the presence of with and without fulvic acid (FA). Dissociation and e …

Background A number of oral diseases, including periodontitis, derive from microbial biofilms and are associated with increased antimicrobial resistance. Despite the widespread use of mouthwashes being used as adjunctive measures to control these biofilms, their prolonged use is not recommended due to various side effects. Therefore, alternative broad-spectrum antimicrobials that minimise these effects are highly sought after. Carbohydrate derived fulvic acid (CHD-FA) is an organic acid which has previously demonstrated to be microbiocidal against Candida albicans biofilms, therefore, the aims of this study were to evaluate the antibacterial activity of CHD-FA against orally derived biofilms and to investigate adjunctive biological effects. Methods Minimum inhibitory concentrations were evaluated for CHD-FA and chlorhexidine (CHX) against a range of oral bacteria using standardised microdilution testing for planktonic and sessile. Scanning electron microscopy was also employed to visualise changes in oral biofilms after antimicrobial treatment. Cytotoxicity of these compounds was assessed against oral epithelial cells, and the effect of CHD-FA on host inflammatory markers was assessed by measuring mRNA and protein expression. Results CHD-FA was highly active against all of the oral bacteria tested, including Porphyromonas gingivalis, with a sessile minimum inhibitory concentration of 0.5%. This concentration was shown to kill multi-species biofilms by approximately 90%, levels comparable to that of chlorhexidine (CHX). In a mammalian cell culture model, pretreatment of epithelial cells with buffered CHD-FA was shown to significantly down-regulate key inflammatory mediators, including interleukin-8 (IL-8), after stimulation with a multi-species biofilm. Conclusions Overall, CHD-FA was shown to possess broad-spectrum antibacterial activity, with a supplementary function of being able to down-regulate inflammation. These properties offer an attractive spectrum of function from a naturally derived compound, which could be used as an alternative topical treatment strategy for oral biofilm diseases. Further studies in vitro and in vivo are required to determine the precise mechanism by which CHD-FA modulates the host immune response.

Fulvic acid (FA) is class of compounds of humic substances formed through the degradation of organic substances by chemical and biological processes. FA has been utilized in traditional Chinese medicine and possesses various pharmacological properties. Previously, we reported that FA extracted from …

Overall, CHD-FA was shown to possess broad-spectrum antibacterial activity, with a supplementary function of being able to down-regulate inflammation. These properties offer an attractive spectrum of function from a naturally derived compound, which could be used as an alternative topical treatment …

No severe adverse events occurred, establishing that CHD-FA to be safe at doses up to 40 mL twice daily for a week and that at this dosage CHD-FA acts as an anti-inflammatory agent. These findings confirm earlier animal data.

Fulvic acid (FA) is known to promote electrochemical balance as a donor or a receptor possessing many biomedical functions. Nevertheless, the effect of FA on the anti-cancer activity has not been elucidated. In the current study, we first isolated FA from humus and investigated whether FA regulates …

Alzheimer's disease is a neurodegenerative disorder involving extracellular plaques (amyloid-β) and intracellular tangles of tau protein. Recently, tangle formation has been identified as a major event involved in the neurodegenerative process, due to the conversion of either soluble peptides or oli …

The experiment was conducted to investigate the effects of dietary supplementation of fulvic acid on lipid metabolism of finishing pigs. One hundred eighty crossbred barrows (Landrace × Yorkshire, 60 ± 2.5 kg) were randomly allotted to 5 dietary treatments (36 pigs/treatment) and fed a basal diet su …

Shilajit has been used traditionally in folk medicine for the treatment of a variety of disorders, including syndromes involving excessive complement activation. Extracts of Shilajit contain significant amounts of fulvic acid (FA), and it has been suggested that FA is responsible for many therapeuti …

This article focused on the influences of fulvic acid and humic acid on aluminum speciation in drinking water. Factors including the concentration of residual chlorine and pH value had been concerned. Aluminum species investigated in the experiments included inorganic mononuclear, organic mononuclea …

CHD-FA is a promising topical remedy for drug-resistant wound infections. It accelerated the healing process of wounds infected with methicillin-resistant S. aureus and multidrug-resistant P. aeruginosa in rats, which is linked to both its antimicrobial and anti-inflammatory properties.

Our findings provide a molecular mechanism by which FA inhibits homocysteine-induced COX-2 expression in monocytes, and a basis for using FA in pharmaceutical therapy against inflammation.

A high level of serum resistin has recently been found in patients with a number of cancers, including colorectal cancer (CRC). Hence, resistin may play a role in CRC development. Fulvic acid (FA), a class of humic substances, possesses pharmacological properties. However, the effect of FA on cancer …

The new and improved Spooky2 Remote v2.0 Remote treatments apply healing frequencies at any distance using the recipient's DNA. This was referred to as "Spooky action at a distance" by Einstein. All testers found the new Spooky2 Remote to be significantly better than the earlier model. Advantages of the new Spooky2 Remote include: Can be used for both healing and killing presets. No fatigue during long-term use. DNA can be placed anywhere within the holder. More consistent results. Better frequency response. Protection against sharp edges. Improved indication lights. Simplified DNA insertion and removal. Silent. Spooky2 Boost needed to connect Spooky2 Remote v2.0 to generator can be ordered here: https://www.spooky2-mall.com/product/spooky2-boost-v3-1/ Note: We recommend connecting one Spooky2 Remote v2.0 to one Spooky2 Boost. Safe and Effective Healing Treatment Start your body healing journey with Spooky2 now! This is the best non-drug solution for your body healing. Also, we offer you a 30-day satisfaction guarantee, so you have nothing to lose but your diseases.

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Are 'smart' meter radiation emissions safe - or not? This video measures the pulses from a 'smart' meter and a cell phone. Watch it just above, or on YouTube here

http://www.spooky2-mall.com/ - Thanks to Steve Hernandez for his support and contribution. Biofeedback scanning requires a frequency sweep to be input to the body, plus a system to monitor the results of this. The frequencies which caused the stress are assembled into a program you can save and use to treat the problems found. Spooky Pulse provides the prescription written by your own body – the frequencies found by your scan. Reverse Lookup is to search the Spooky2 database to find frequencies within the tolerance you specify. Check the video for more detail about how to do a biofeedback scan and reverse lookup using spooky2 software. For more videos, please go to the link: http://www.spooky2videos.com/ Download the Free Spooky2 Software and User's Guide here: http://spooky2.com/downloadsPage/inde... Purchase Spooky2 Hardware/Equipment here: http://www.spooky2-mall.com/ Join the Spooky2 Rife for Life Facebook Group here: https://www.facebook.com/groups/spooky2/ Subscribe us for the latest information about Spooky2 rife machine and natural ways for health

Check out the updated video here: https://youtu.be/nOgvVFSgoyE http://www.spooky2-mall.com/ - This video shows how to do an all full system scan. The sweep can be administered in contact mode and the scan results can be saved as a program to your custom database. This video starts from the hardware introduction, hardware connection to the software setting.

Treatment with alternating electric fields at an intermediate frequency (100-300 kHz), referred to as tumor treating fields (TTF) therapy, inhibits cancer cell proliferation. In the present study, we demonstrated that TTF application suppressed the metastatic potential of U87 and U373 glioblastoma c …

Abstract. Tumor treating fields (TTFields) are low-intensity electric fields alternating at an intermediate frequency (200kHz), which have been demonstrated to