2016

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Trehalose Ameliorates Nonalcoholic Fatty Liver Disease by Regulating IRE1α-TFEB Signaling Pathway - PubMed
Trehalose Ameliorates Nonalcoholic Fatty Liver Disease by Regulating IRE1α-TFEB Signaling Pathway - PubMed
Nonalcoholic fatty liver disease (NAFLD), characterized by hepatic lipid deposition, is one of the most prevalent chronic metabolic disorders globally, and its pharmaceutical treatments are still limited. Excessive lipid accumulation triggers endoplasmic reticulum (ER) stress and autophagy flux dysf …
·pubmed.ncbi.nlm.nih.gov·
Trehalose Ameliorates Nonalcoholic Fatty Liver Disease by Regulating IRE1α-TFEB Signaling Pathway - PubMed
Glucosamine Inhibits the Proliferation of Hepatocellular Carcinoma Cells by Eliciting Apoptosis, Autophagy, and the Anti‐Warburg Effect - Samizu - 2025 - Scientifica - Wiley Online Library
Glucosamine Inhibits the Proliferation of Hepatocellular Carcinoma Cells by Eliciting Apoptosis, Autophagy, and the Anti‐Warburg Effect - Samizu - 2025 - Scientifica - Wiley Online Library
Although glucosamine (GlcN) exhibits antitumor effects, its mechanism of action remains controversial. Additionally, its impact on hepatocellular carcinoma (HCC) is not well understood. This study ai...
·onlinelibrary.wiley.com·
Glucosamine Inhibits the Proliferation of Hepatocellular Carcinoma Cells by Eliciting Apoptosis, Autophagy, and the Anti‐Warburg Effect - Samizu - 2025 - Scientifica - Wiley Online Library
A Comparative Review of Alternative Fucoidan Extraction Techniques from Seaweed
A Comparative Review of Alternative Fucoidan Extraction Techniques from Seaweed
Fucoidan is a sulfated polysaccharide found in brown seaweed. Due to its reported biological activities, including antiviral, antibacterial and anti-inflammatory activities, it has garnered significant attention for potential biomedical applications. However, the direct relationship between fucoidan extracts’ chemical structures and bioactivities is unclear, making it extremely challenging to predict whether an extract will possess a given bioactivity. This relationship is further complicated by a lack of uniformity in the recent literature in terms of the assessment and reporting of extract properties, yield and chemical composition (e.g., sulfate, fucose, uronic acid and monosaccharide contents). These inconsistencies pose significant challenges when directly comparing extraction techniques across studies. This review collected data on extract contents and properties from a selection of available studies. Where information was unavailable directly, efforts were made to extrapolate data. This approach enabled a comprehensive examination of the correlation between extraction techniques and the characteristics of the resulting extracts. A holistic framework is presented for the selection of fucoidan extraction methods, outlining key heuristics to consider when capturing the broader context of a seaweed bioprocess. Future work should focus on developing knowledge within these heuristic categories, such as the creation of technoeconomic models of each extraction process. This framework should allow for a robust extraction selection process that integrates process scale, cost and constraints into decision making. Key quality attributes for biologically active fucoidan are proposed, and areas for future research are identified, such as studies for specific bioactivities aimed at elucidating fucoidan’s mechanism of action. This review also sets out future work required to standardize the reporting of fucoidan extract data. Standardization could positively enhance the quality and depth of data on fucoidan extracts, enabling the relationships between physical, chemical and bioactive properties to be identified. Recommendations on best practices for the production of high-quality fucoidan with desirable yield, characteristics and bioactivity are highlighted.
·mdpi.com·
A Comparative Review of Alternative Fucoidan Extraction Techniques from Seaweed
3 Steps to Reverse Cataracts - America's Favorite Eye Doctor - Eye Dis (...)
3 Steps to Reverse Cataracts - America's Favorite Eye Doctor - Eye Dis (...)
3 Steps to Reverse Cataracts without Surgery by a Former Eye Surgeon! Here is a sample of items covered in the webinar.  1) Can eye drops cure cataracts and what eye drops work the best? 2) Focal scurvy might be a cause of cataracts. 3) Why Cataract surgery might lead to macular degeneration and...
·healingtheeye.com·
3 Steps to Reverse Cataracts - America's Favorite Eye Doctor - Eye Dis (...)
4 Ways to Keep From Losing Your Eyesight Cataracts GreenMedInfo
4 Ways to Keep From Losing Your Eyesight Cataracts GreenMedInfo
4 Ways to Keep From Going Blind (Cataracts) As we age our eyes gradually cloud over, with unchecked cataracts the leading cause of blindness. Here are 4 simple things you can do to make sure your eyes stay youthful late into life
·greenmedinfo.com·
4 Ways to Keep From Losing Your Eyesight Cataracts GreenMedInfo
Cataracts water, energy, light, and aging
Cataracts water, energy, light, and aging
Considerable amounts of some chemicals, such as sodium citrate, are allowed to add to the weight of the meat. The use of ozone and hydrogen peroxide to deodorize meat causes instantaneous oxidative changes, including lipid peroxidation and protein carbonyl formation, as well as increasing water retention.
·raypeat.com·
Cataracts water, energy, light, and aging
Dipyridamole Eye Drops
Dipyridamole Eye Drops
Dipyridamole is a drug in use for the past 55 years for treating heart conditions. In 2012 a breakthrough was reached when Moshe Rogosnitzky discovered that dipyridamole eye drops are effective in treating difficult eye conditions such as dry eye, pterygium, pinguecula, cataract, nevus and a variety of other eye disorders.
·dipyridamoleeyedrops.org·
Dipyridamole Eye Drops
Lanosterol reverses protein aggregation in cataracts Nature
Lanosterol reverses protein aggregation in cataracts Nature
Nature - In a study of the genetic basis of congenital cataract formation in two families, Kang Zhang and colleagues demonstrate that lanosterol, a sterol present naturally in the lens, can prevent...
·nature.com·
Lanosterol reverses protein aggregation in cataracts Nature
Only the Bible Can Explain the Ice Age - YouTube
Only the Bible Can Explain the Ice Age - YouTube
📕 Get a FREE copy of _The Creation Answer Book_ here: https://creation.com/22cab It is one of our most recommended resources. Chapter 16 deals with ice ages. --- We are told that there have been multiple ice ages in Earth’s history. What does that even mean? What is an ice age? What physical evidence would one leave? And most importantly of all, _how does an ice age start (and later, stop)?_ Secular scientists have major trouble modelling how even _one_ ice age could start in the real world—never mind _multiple ice ages!_ And they have _many_ associated ice age mysteries to explain—such as the post-ice age extinction event. The biblical post-Flood Ice Age model, on the other hand, does a good job of explaining the observed evidence! After all, if the Bible is a true record of history, it makes sense that it would have strong explanatory power when trying to make sense of the past! Join geologist, Dr Tas Walker, for a fascinating exploration of the mysteries of the Ice Age. ⏳ CHAPTERS 00:00 Teaser 00:35 *Introduction:* What is the mystery of the Ice Age? 01:36 Physical evidence of a past Ice Age 03:29 → Scientist originally wouldn’t believe the evidence! 04:31 What was the extent of the ice in the Ice Age? 05:39 The mystery: What caused the Ice Age? 06:29 What solutions have been put forward? 08:02 *The Secular Ice Age Model: Milankovitch cycles* 10:46 → Problem: Milankovitch cycles don’t produce enough cooling! 11:21 → The secondary hypothesis: Positive feedback from CO2 12:21 → Secular scientists have concluded Earth’s climate is an unstable system 12:59 → Climate alarmism is a by-product of an unbiblical Ice Age model 14:20 → Problem: Positive feedback (producing cooling) isn’t enough; much more precipitation is needed! 15:51 → Problem: The geologic record doesn’t match expectations about past ice ages 21:07 → Mysteries within mysteries for the secular theory 23:03 *The Biblical Ice Age Model: The aftermath of the Flood—which was a catastrophic, global, tectonic event* 24:20 → Global volcanic activity blocked sunlight 26:28 → Global tectonic activity warmed the oceans 27:20 → Solving mysteries around Ice Age animals 30:14 → Earth’s climate is stable! 34:22 → Ice Age land bridges help to explain human and animal dispersal 38:37 → Solving the mystery of the mass extinction event at the end of the Ice Age 43:34 Why secular ‘Snowball Earth’? ideas fail 45:40 → Solving the mystery of the lush, green Sahara 47:44 *Conclusion:* The Bible’s account of history makes sense of the world we live in! ✍️ LINKS AND SHOW NOTES • What about ice ages? (Ch. 16 of The Creation Answers Book) – https://creation.com/cab-16 • The unique post-Flood Ice Age – https://creation.com/ice-age-model • What caused the Ice Age? https://creation.com/what-caused-ice-age • Was There An Ice Age? https://youtu.be/vAAZiMcNjLo • Over-kill, over-chill, or over-ill? https://creation.com/kill-chill-ill • Astronomical troubles for the astronomical hypothesis of ice ages – https://creation.com/ice-age-troubles • Ice Age Questions and Answers – https://creation.com/ice-age-questions-and-answers • The Woolly Mammoth – https://creation.com/woolly-mammoth • How did 90% of large Australian Ice Age animals go extinct? https://creation.com/australian-ice-age-animal-extinction 📚 HELPFUL RESOURCES • The Great Ice Age (streaming) – https://creation.com/s/35-8-637 • The Ice Age—Only the Bible Can Explain It (streaming) – https://creation.com/s/35-8-612 • Frozen in Time (book) https://creation.com/s/10-2-169 • The Mammoth & the Ice Age (streaming) – https://creation.com/s/35-8-514 • Life in the Great Ice Age (children’s book) – https://creation.com/s/10-1-024 • Ice Cores and the Age of the Earth (book) – https://creation.com/s/10-3-016 • The Frozen Record (book) – https://creation.com/s/10-3-111 • Biblical Geology 101 (book) – https://creation.com/s/10-2-675 💙 SOCIAL MEDIA ► Facebook: https://www.facebook.com/creationministries ► TikTok: https://www.tiktok.com/@creationministries ► Instagram: https://www.instagram.com/creationministries ► X / Twitter: https://twitter.com/creationnews ► eNewsletter: https://creation.com/infobytes 📅 EVENTS We present at _hundreds_ of events around the world each year. To see what events are happening near you, or to request a creation presentation in _your_ Church (or other gathering) visit: https://creation.com/events Thanks for watching!
·youtube.com·
Only the Bible Can Explain the Ice Age - YouTube
The Harbingers Of Lightning & 2025! | Jonathan Cahn Prophetic - YouTube
The Harbingers Of Lightning & 2025! | Jonathan Cahn Prophetic - YouTube
Has God sent us not 1, not 2, not 3 – but FOUR dramatic signs on New Year’s Eve as a warning of things to come, of America’s future, and what we need to do now? And can we afford to ignore them? Check out the new prophetic message by Jonathan Cahn. TO SUBSCRIBE: https://www.youtube.com/channel/UCjsoQpzk-XQOt4YM6nzq_-Q?sub_confirmation=1 To receive Free Gifts, Prophetic Updates, Get in touch with Jonathan’s Ministry, or be part of the Great Commission, Go to HopeOfTheWorld.org or Click here http://www.HopeOfTheWorld.org 📬Or write to: Hope of the World, Box 1111, Lodi, NJ 07644 To get Jonathan’s newest prophetic book: The Dragon's Prophecy - or his other bestsellers: The Josiah Manifesto, The Return Of The Gods, The Harbinger II, The Oracle, The Paradigm, The Book of Mysteries, The Harbinger, & more – Go to Amazon or anywhere books are sold. Jonathan Cahn has been called the prophetic voice of his generation and is known for unlocking the deep mysteries and revelations of God’s Word. He leads Hope of the World, a worldwide ministry of outreach of God’s Word to all nations, and His love and compassion to the world’s most needy. 🖥 Follow Jonathan Cahn: 👇 Instagram: https://www.instagram.com/jonathan.cahn/ Facebook: https://www.facebook.com/jonathancahn.official/ X: https://twitter.com/Jonathan_Cahn TikTok: https://www.tiktok.com/@official.jonathancahn Telegram: https://t.me/officialJonathanCahn WhatsApp: https://whatsapp.com/channel/0029ValHKmJ8aKvEh7jYMO36 👉Hope Of The World Ministries: https://www.hopeoftheworld.org 📚Jonathan Cahn's Books: https://booksbyjonathancahn.com #jonathancahn #jonathancahnlatest #propheticword
·youtube.com·
The Harbingers Of Lightning & 2025! | Jonathan Cahn Prophetic - YouTube
Damascus Has Fallen, But What Comes Next? - YouTube
Damascus Has Fallen, But What Comes Next? - YouTube
Dr. Bill Salus discusses the unfulfilled FUTURE WAR Prophecies related to Damascus and Syria with Janie Duvall. Isaiah 17, Jeremiah 49:23-27 and Psalm 83 are among the topics explored and explained. Click the bell icon next to the SUBSCRIBE button to get alerts when a new video is uploaded. Visit Website: http://prophecydepot.com Read Daily News Reports: http://prophecynewsstand.blogspot.com Subscribe to Newsletter: http://prophecydepotministries.net Bill's Articles: http://prophecydepotministries.net/bills-articles/ Products: http://ecommerce.solutionsimplicity.com/index
·youtube.com·
Damascus Has Fallen, But What Comes Next? - YouTube
Exposure to an enriched environment and fucoidan supplementation ameliorate learning and memory function in rats subjected to global cerebral ischemia - ScienceDirect
Exposure to an enriched environment and fucoidan supplementation ameliorate learning and memory function in rats subjected to global cerebral ischemia - ScienceDirect
An enriched environment (EE) constitutes a proficient strategy that instigates social, cognitive, and motor faculties, fostering healing and heighteni…
·sciencedirect.com·
Exposure to an enriched environment and fucoidan supplementation ameliorate learning and memory function in rats subjected to global cerebral ischemia - ScienceDirect
EFFECT OF D-ALLULOSE ON INSULIN RESISTANCE AND ENDURANCE ABILITY: IS D-ALLULOSE AN EXERCISE MIMETIC? - PMC
EFFECT OF D-ALLULOSE ON INSULIN RESISTANCE AND ENDURANCE ABILITY: IS D-ALLULOSE AN EXERCISE MIMETIC? - PMC
D-Allulose, a rare sugar and C3-epimer of D-fructose has been proposed as a candidate for dietary restriction mimetics via inhibition of glycolysis. Anti-hyperglycemic and anti-obesity effects have been reported in rodents and human subjects. Here, ...
·pmc.ncbi.nlm.nih.gov·
EFFECT OF D-ALLULOSE ON INSULIN RESISTANCE AND ENDURANCE ABILITY: IS D-ALLULOSE AN EXERCISE MIMETIC? - PMC
Dr. David Geier - Orthopedic surgeon, sports medicine, and anti-aging and regenerative medicine specialist in Charleston, South Carolina | Dr Geier
Dr. David Geier - Orthopedic surgeon, sports medicine, and anti-aging and regenerative medicine specialist in Charleston, South Carolina | Dr Geier
I created this website to discuss injuries, injury treatments and injury prevention with athletes and active people so that you can stay healthy and perform your best. It has never been my intention to use it to promote my medical practice. However, I often get questions from people here in Charleston and all around the world […]
·drdavidgeier.com·
Dr. David Geier - Orthopedic surgeon, sports medicine, and anti-aging and regenerative medicine specialist in Charleston, South Carolina | Dr Geier
Dr. David Geier - YouTube
Dr. David Geier - YouTube
I want to help you feel, look, and perform your best regardless of age or injury. I'm a triple-board certified orthopedic surgeon, sports medicine specialist, and anti-aging and regenerative medicine expert. I believe that the best way to return to peak performance after a bone or joint injury is to get the injury to heal without surgery. But it’s not just about your injury and recovery. It’s about getting you back to what you love to do – your favorite sport, exercising every day, or even just playing with your kids and getting through your work day without pain.
·youtube.com·
Dr. David Geier - YouTube