The traditional Okinawa diet is centered around vegetables, the most nutrient-dense food group. What would happen if your diet followed the same? Subscribe to NutritionFacts.org’s free newsletter to receive our B12 infographic that covers the latest research takeaways and Dr. Greger’s updated recommendations: https://nutritionfacts.org/subscribe/ Yes, there are purple sweet potatoes (Yum!) Why do those eating plant-based diets live longer? There are all sorts of mechanisms I find fascinating: Methionine Restriction as a Life Extension Strategy (https://nutritionfacts.org/video/methionine-restriction-as-a-life-extension-strategy/) Why Do We Age? (https://nutritionfacts.org/video/why-do-we-age/) Caloric Restriction vs. Animal Protein Restriction (https://nutritionfacts.org/video/caloric-restriction-vs-animal-protein-restriction/) Turning the Clock Back 14 Years (https://nutritionfacts.org/video/turning-the-clock-back-14-years/) Longer Life Within Walking Distance (https://nutritionfacts.org/video/longer-life-within-walking-distance/) Prevent Cancer from Going on TOR (https://nutritionfacts.org/video/prevent-cancer-from-going-on-TOR/) Does Meditation Affect Cellular Aging? (https://nutritionfacts.org/video/does-meditation-affect-cellular-aging/) Telomeres: Cap It All Off with Diet (https://nutritionfacts.org/video/telomeres-cap-it-all-off-with-diet/) Nuts May Help Prevent Death (https://nutritionfacts.org/video/nuts-may-help-prevent-death) Increased Lifespan from Beans (https://nutritionfacts.org/video/increased-lifespan-from-beans/) Fruits and Longevity: How Many Minutes per Mouthful? (https://nutritionfacts.org/video/fruits-veggies-and-longevity-how-many-minutes-per-mouthful/) And a couple of new ones: The Benefits of Calorie Restriction for Longevity (https://nutritionfacts.org/video/the-benefits-of-calorie-restriction-for-longevity/) and Does Intermittent Fasting Increase Human Life Expectancy? (https://nutritionfacts.org/video/does-intermittent-fasting-increase-human-life-expectancy/) Have a question about this video? Leave it in the comment section at http://nutritionfacts.org/video/flashback-friday-the-okinawa-diet-living-to-100 and someone on the NutritionFacts.org team will try to answer it. Want to get a list of links to all the scientific sources used in this video? Click on Sources Cited at http://nutritionfacts.org/video/flashback-friday-the-okinawa-diet-living-to-100. You’ll also find a transcript and acknowledgements for the video, my blog and speaking tour schedule, and an easy way to search (by translated language even) through our videos spanning more than 2,000 health topics. If you’d rather watch these videos on YouTube, subscribe to my YouTube Channel here: https://www.youtube.com/subscription_center?add_user=nutritionfactsorg Thanks for watching. I hope you’ll join in the evidence-based nutrition revolution! -Michael Greger, MD FACLM Captions for this video are available in several languages. To find yours, click on the settings wheel on the lower-right of the video and then "Subtitles/CC." Do you have feedback about the translations in this video? Please share it here along with the title of the video and language: https://nutritionfacts.zendesk.com/hc/requests/new Images thanks to cotaro70s via Flickr, klaber, jarmoluk, Taken, Joon2079, PublicDomainPictures, PublicDomainImages, Kaz, Activedia, margenauer, bykst, HebiFot via Pixabay, teen00000 and Ratana Prongjai via 123rf. https://NutritionFacts.org • Subscribe: https://nutritionfacts.org/subscribe • Donate: https://nutritionfacts.org/donate • Podcast : https://nutritionfacts.org/audio • Facebook: www.facebook.com/NutritionFacts.org • Twitter: www.twitter.com/nutrition_facts • Instagram: www.instagram.com/nutrition_facts_org • Books (including the NEW How Not to Diet Cookbook): https://nutritionfacts.org/books • Shop: https://drgreger.org

Dr. Valter Longo and I discuss the science of longevity and the powerful effects of fasting and the Fasting Mimicking Diet.

A diet that includes a moderate intake of fat and fruits and vegetables, and avoidance of high carbohydrates, is associated with lower risk of death, research with more than 135,000 people across five continents has shown.

Restricting calorie consumption is one of the few proven ways to combat aging. Now researchers have developed a computer algorithm that predicts which genes can be "turned off" to create the same anti-aging effect as calorie restriction. The findings could lead to the development of new drugs to treat aging.

From caring for your feet to getting enough magnesium, Dr. Lipman hones in on what really matters for keeping yourself healthy, active, and vibrant.

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Bipolar disorder may involve accelerated epigenetic aging, which could explain why persons with the disorder are more likely to have -- and die from -- age-related diseases, according to researchers.

Objectives To evaluate the associations of regular glucosamine use with all-cause and cause-specific mortality in a large prospective cohort. Methods This population-based prospective cohort study included 495 077 women and men (mean (SD) age, 56.6 (8.1) years) from the UK Biobank study. Participants were recruited from 2006 to 2010 and were followed up through 2018. We evaluated all-cause mortality and mortality due to cardiovascular disease (CVD), cancer, respiratory and digestive disease. HRs and 95% CIs for all-cause and cause-specific mortality were calculated using Cox proportional hazards models with adjustment for potential confounding variables. Results At baseline, 19.1% of the participants reported regular use of glucosamine supplements. During a median follow-up of 8.9 years (IQR 8.3–9.7 years), 19 882 all-cause deaths were recorded, including 3802 CVD deaths, 8090 cancer deaths, 3380 respiratory disease deaths and 1061 digestive disease deaths. In multivariable adjusted analyses, the HRs associated with glucosamine use were 0.85 (95% CI 0.82 to 0.89) for all-cause mortality, 0.82 (95% CI 0.74 to 0.90) for CVD mortality, 0.94 (95% CI 0.88 to 0.99) for cancer mortality, 0.73 (95% CI 0.66 to 0.81) for respiratory mortality and 0.74 (95% CI 0.62 to 0.90) for digestive mortality. The inverse associations of glucosamine use with all-cause mortality seemed to be somewhat stronger among current than non-current smokers (p for interaction=0.00080). Conclusions Regular glucosamine supplementation was associated with lower mortality due to all causes, cancer, CVD, respiratory and digestive diseases.

Every cell in our body contains the complete DNA library. So-called methyl groups regulate that in body tissues only the genetic information is expressed that is indeed needed in this tissue. Now, for the first time, researchers verified that a lack of methyl groups in the gene body leads to an incorrect gene activation and, as a consequence, may lead to the emergence of cancer.

With the recent rise in popularity of naturally-derived supplements to maintain a healthy body, there has been a great deal of attention toward development of the so-called "brain foods", which can enhance brain function. Of particular importance is the natural red pigment astaxanthin (ASX) abundant in both salmon and in crustaceans such as shrimp and crab. ASX has a powerful antioxidant effect, and is capable of penetrating the blood-brain barrier, entering the brain, where it acts directly on nerve cells. ASX is also known to have a neuroprotective effect. However, there are many unanswered questions as to the effects of ASX on hippocampal function, especially whether or not it can increase the neuroplasticity of the hippocampus.

Is memory loss and decreased brain power inevitable as we age? Many people in their 40s, 50s and beyond are told that it is and there is nothing that can be done about it. Is that true? Of course not

It saddens me to see older women diagnosed with "osteopenia" or "osteoporosis" listening to their doctors and taking supplemental calcium and even problematic drugs called bisphosphonates. These are irrational, dogmatic, harmful approaches to the problem of degrading bone as we age

There is a food that offers the best of both worlds, significantly improving our ability to detox carcinogens like diesel fumes and decreasing inflammation in our airways all the while improving our respiratory defences against infections. Subscribe to NutritionFacts.org’s free newsletter to receive our B12 infographic that covers the latest research takeaways and Dr. Greger’s updated recommendations: https://nutritionfacts.org/subscribe/ I love this video! I’ve been reading about the terrible effects of air pollution for a long time, but finally there’s at least something we can do that doesn’t involve having to uproot your family and move out to the countryside. Prolonged Liver Function Enhancement from Broccoli (http://nutritionfacts.org/video/prolonged-liver-function-enhancement-from-broccoli/) is the previous video I referred to. More cruciferocity here: • Lung Cancer Metastases and Broccoli (http://nutritionfacts.org/video/lung-cancer-metastases-and-broccoli/) • Prolonged Liver Function Enhancement from Broccoli (http://nutritionfacts.org/video/prolonged-liver-function-enhancement-from-broccoli/) • Breast Cancer Survival Vegetable (http://nutritionfacts.org/video/breast-cancer-survival-vegetable/) But there’s a secret to maximizing the benefits. See Second Strategy to Cooking Broccoli (http://nutritionfacts.org/video/second-strategy-to-cooking-broccoli/). What about broccoli sprout pills? see Broccoli: Sprouts vs. Supplements (http://nutritionfacts.org/video/broccoli-sprouts-vs-supplements/). Speaking of respiratory inflammation, what about dietary approaches to asthma? See: • Preventing Asthma With Fruits and Vegetables (http://nutritionfacts.org/video/preventing-asthma-with-fruits-and-vegetables/) • Treating Asthma With Fruits and Vegetables (http://nutritionfacts.org/video/treating-asthma-with-fruits-and-vegetables/) • Treating Asthma With Plants vs. Supplements? (http://nutritionfacts.org/video/treating-asthma-with-plants-vs-supplements/) • Treating Asthma and Eczema with Plant-based Diets (http://nutritionfacts.org/video/treating-asthma-and-eczema-with-plant-based-diets/) • Vitamin D for Asthma (http://nutritionfacts.org/video/vitamin-D-for-asthma) • How to Treat Asthma with a Low Salt Diet (http://nutritionfacts.org/video/How-to-Treat-Asthma-with-a-Low-Salt-Diet) There are sources of indoor pollution too, see Throw Household Products off the Scent (http://nutritionfacts.org/video/throw-household-products-off-the-scent/). There is one way what we eat can directly impact air pollution beyond just personal protection. Check out Diet & Climate Change: Cooking Up a Storm (http://nutritionfacts.org/video/diet-and-climate-change-cooking-up-a-storm/). Have a question about this video? Leave it in the comment section at http://nutritionfacts.org/video/best-food-to-counter-the-effects-of-air-pollution and someone on the NutritionFacts.org team will try to answer it. Want to get a list of links to all the scientific sources used in this video? Click on Sources Cited at http://nutritionfacts.org/video/best-food-to-counter-the-effects-of-air-pollution. You’ll also find a transcript and acknowledgements for the video, my blog and speaking tour schedule, and an easy way to search (by translated language even) through our videos spanning more than 2,000 health topics. If you’d rather watch these videos on YouTube, subscribe to my YouTube Channel here: https://www.youtube.com/subscription_center?add_user=nutritionfactsorg Thanks for watching. I hope you’ll join in the evidence-based nutrition revolution! -Michael Greger, MD FACLM Image credit: pixakame via pixabay. Image has been modified. https://NutritionFacts.org • Subscribe: https://nutritionfacts.org/subscribe • Donate: https://nutritionfacts.org/donate • Podcast : https://nutritionfacts.org/audio • Facebook: www.facebook.com/NutritionFacts.org • Twitter: www.twitter.com/nutrition_facts • Instagram: www.instagram.com/nutrition_facts_org • Books (including the NEW How Not to Diet Cookbook): https://nutritionfacts.org/books • Shop: https://drgreger.org

Ancient dietary practices based on analyzing the fiber content of fossilized human waste can give us insights for combatting the modern obesity epidemic. Subscribe to NutritionFacts.org’s free newsletter to receive our B12 infographic that covers the latest research takeaways and Dr. Greger’s updated recommendations: https://nutritionfacts.org/subscribe/ Isn’t that a really fascinating mechanism? All along I was thinking of fiber more from just an energy density perspective (as in my video Eating More to Weigh Less http://nutritionfacts.org/video/eating-more-to-weigh-less/), but the appetite-suppressing hormones are a whole new frontier. That underscores the urgency of the fact that 96% of Americans don’t even reach the recommended minimum intake of fiber (see my video Do Vegetarians Get Enough Protein? http://nutritionfacts.org/video/do-vegetarians-get-enough-protein/). Other paleo videos include: • Paleo Diets May Negate Benefits of Exercise (http://nutritionfacts.org/video/paleo-diets-may-negate-benefits-of-exercise/) • Paleolithic Lessons (http://nutritionfacts.org/video/paleolithic-lessons/) • The Problem With the Paleo Diet Argument (http://nutritionfacts.org/video/the-problem-with-the-paleo-diet-argument/) For bowel function in the modern age, see, for example, How Many Bowel Movements Should You Have Every Day? (http://nutritionfacts.org/video/how-many-bowel-movements-should-you-have-every-day) and Should You Sit, Squat, or Lean During a Bowel Movement? (http://nutritionfacts.org/video/should-you-sit-squat-or-lean-during-a-bowel-movement). My latest on fiber: • Diverticulosis: When Our Most Common Gut Disorder Hardly Existed (http://nutritionfacts.org/video/diverticulosis-when-our-most-common-gut-disorder-hardly-existed) • The Five to One Fiber Rule (http://nutritionfacts.org/video/the-five-to-one-fiber-rule) • Is the Fiber Theory Wrong? (http://nutritionfacts.org/video/is-the-fiber-theory-wrong) And my latest on what your gut bacteria can do for you: • Microbiome: The Inside Story (http://nutritionfacts.org/video/microbiome-the-inside-story) • Prebiotics: Tending Our Inner Garden (http://nutritionfacts.org/video/prebiotics-tending-our-inner-garden) • What’s Your Gut Microbiome Enterotype? (http://nutritionfacts.org/video/whats-your-gut-microbiome-enterotype) • How to Change Your Enterotype (http://nutritionfacts.org/video/how-to-change-your-enterotype) More paleo diet videos on the way—and more microbiome too! Have a question for Dr. Greger about this video? Leave it in the comment section at http://nutritionfacts.org/video/paleopoo-what-we-can-learn-from-fossilized-feces and he'll try to answer it! Image Credit: James St. John and Linda Spashett via Flickr, Eleifert via Wikimedia Commons, and Pixel-mixer and cegoh via Pixabay. https://NutritionFacts.org • Subscribe: https://nutritionfacts.org/subscribe • Donate: https://nutritionfacts.org/donate • Podcast : https://nutritionfacts.org/audio • Facebook: www.facebook.com/NutritionFacts.org • Twitter: www.twitter.com/nutrition_facts • Instagram: www.instagram.com/nutrition_facts_org • Books (including the NEW How Not to Diet Cookbook): https://nutritionfacts.org/books • Shop: https://drgreger.org

The link between Parkinson’s and dairy may not just be explained by the pesticides and lactose. Subscribe to NutritionFacts.org’s free newsletter to receive our B12 infographic that covers the latest research takeaways and Dr. Greger’s updated recommendations: https://nutritionfacts.org/subscribe/ Dairy and Parkinson’s? See Preventing Parkinson’s Disease With Diet (http://nutritionfacts.org/video/preventing-parkinsons-disease-with-diet) Lactose and Parkinson’s? See Could Lactose Explain the Milk - Parkinson’s Disease Link? (http://nutritionfacts.org/video/could-lactose-explain-milk-parkinsons-disease-link) Uric acid as an antioxidant? I’ve touched on that before in Miocene Meteorites and Uric Acid (http://nutritionfacts.org/video/miocene-meteorites-and-uric-acid/). If levels are too high consider cutting down on Flesh and Fructose (http://nutritionfacts.org/video/flesh-and-fructose/) and eating cherries (see Gout Treatment with a Cherry on Top (http://nutritionfacts.org/video/gout-treatment-with-a-cherry-on-top/) and Treating Gout with Cherry Juice (http://nutritionfacts.org/video/treating-gout-with-cherry-juice/)). Check out Preventing Gout Attacks with Diet (http://nutritionfacts.org/video/preventing-gout-attacks-with-diet/). Can a plant-based diet be used to treat Parkinson’s? See Treating Parkinson’s Disease With Diet (http://nutritionfacts.org/video/treating-parkinsons-disease-with-diet/). Any plant foods in particular that may help? Try nightshade veggies: • Is Something in Tobacco Protective Against Parkinson’s Disease? (http://nutritionfacts.org/topics/Is-something-in-tobacco-protective-against-parkinsons-disease) • Peppers and Parkinson’s: The Benefits of Smoking Without the Risks? (http://nutritionfacts.org/video/peppers-and-parkinsons-the-benefits-of-smoking-without-the-risks) Have a question about this video? Leave it in the comment section at http://nutritionfacts.org/video/parkinsons-disease-and-the-uric-acid-sweet-spot and someone on the NutritionFacts.org team will try to answer it. Want to get a list of links to all the scientific sources used in this video? Click on Sources Cited at http://nutritionfacts.org/video/parkinsons-disease-and-the-uric-acid-sweet-spot. You’ll also find a transcript of the video, my blog and speaking tour schedule, and an easy way to search (by translated language even) through our videos spanning more than 2,000 health topics. If you’d rather watch these videos on YouTube, subscribe to my YouTube Channel here: https://www.youtube.com/subscription_center?add_user=nutritionfactsorg Thanks for watching. I hope you’ll join in the evidence-based nutrition revolution! -Michael Greger, MD FACLM Image Credit: Meditations via Pixabay. Image has been modified. https://NutritionFacts.org • Subscribe: https://nutritionfacts.org/subscribe • Donate: https://nutritionfacts.org/donate • Podcast : https://nutritionfacts.org/audio • Facebook: www.facebook.com/NutritionFacts.org • Twitter: www.twitter.com/nutrition_facts • Instagram: www.instagram.com/nutrition_facts_org • Books (including the NEW How Not to Diet Cookbook): https://nutritionfacts.org/books • Shop: https://drgreger.org

Bioidentical Estrogen Hormones Could Have Saved 50,000 Lives, New Yale Study.

Supplement Facts & Directions Supplement Facts Serving Size: 400 milligrams Servings Per Container: Varies Amount Per Serving % Daily Value* Pine Bark Extract (Pinus massoniana) 400 mg Standardized to contain >95% Proanthocyanidin 380 mg † * Percent Daily Values are based on a 2,000 calorie diet.† Daily Value Not Established ‡ These supplement facts may vary from the product you receive.    Please call for exact numbers. Other Ingredients: None Free of:  Sugar, Soy, Dairy, Yeast, Gluten, Corn & Additives. Directions:  As a dietary supplement, take 400 mg (3/16 tsp) once daily, or as directed by a physician. Accurate gram weight scale recommended. Warning: If you are pregnant, nursing, taking any medications or have any medical condition consult your physician before use. DO NOT use with blood-thinning agents. Keep out of reach of children. READ MORE BELOW   Product Details Pine bark extract

Old mice ran around like young animals again, and showed signs of improved memory, after receiving injections of blood taken from 18-year-old people

The improvement of arterial function on a whole food, plant-based diet is so pronounced that cardiac patients can achieve a 90% reduction in angina attacks. Subscribe to NutritionFacts.org’s free newsletter to receive our B12 infographic that covers the latest research takeaways and Dr. Greger’s updated recommendations: https://nutritionfacts.org/subscribe/ Wait a second, though. The Ornish program involves a number of other healthy lifestyle interventions such as exercise. How do we know it was the diet? That’s precisely the topic of my next video, Plant-Based Treatment for Angina (http://nutritionfacts.org/video/plant-based-treatment-for-angina). What would happen if instead of going on a plant-based diet, you went on a low carb diet. You don’t want to know. But if you do, here you go: Low Carb Diets and Coronary Blood Flow (http://nutritionfacts.org/video/low-carb-diets-and-coronary-blood-flow/). In my last video I covered the green tea angle. If you missed it, check out Tea and Artery Function (http://nutritionfacts.org/video/tea-and-artery-function). What effects might other foods have? See: • Eggs and Arterial Function (http://nutritionfacts.org/video/eggs-and-arterial-function/) • Walnuts and Artery Function (http://nutritionfacts.org/video/walnuts-and-artery-function/) • Dark Chocolate and Artery Function (http://nutritionfacts.org/video/dark-chocolate-and-artery-function/) • Coffee and Artery Function (http://nutritionfacts.org/video/coffee-and-artery-function/) • Fatty Meals May Impair Artery Function (http://nutritionfacts.org/video/fatty-meals-may-impair-artery-function) • Olive Oil and Artery Function (http://nutritionfacts.org/video/olive-oil-and-artery-function) Have a question for Dr. Greger about this video? Leave it in the comment section at http://nutritionfacts.org/video/plant-based-diets-and-artery-function and he'll try to answer it! Image Credit: Ryan via Flickr. https://NutritionFacts.org • Subscribe: https://nutritionfacts.org/subscribe • Donate: https://nutritionfacts.org/donate • Podcast : https://nutritionfacts.org/audio • Facebook: www.facebook.com/NutritionFacts.org • Twitter: www.twitter.com/nutrition_facts • Instagram: www.instagram.com/nutrition_facts_org • Books (including the NEW How Not to Diet Cookbook): https://nutritionfacts.org/books • Shop: https://drgreger.org

Even without an exercise component, a plant-based diet can reduce angina attacks 90% within 24 days. Subscribe to NutritionFacts.org’s free newsletter to receive our B12 infographic that covers the latest research takeaways and Dr. Greger’s updated recommendations: https://nutritionfacts.org/subscribe/ See a comparison of the arterial function of vegetarians versus omnivores in my previous video: Plant-Based Diets and Artery Function (http://nutritionfacts.org/video/plant-based-diets-and-artery-function). Or compairing the Arteries of Vegans vs. Runners (http://nutritionfacts.org/video/arteries-of-vegans-vs-runners/). If those on plant-based diets aren’t getting a regular, reliable source of vitamin B12, though, their artery health can suffer. See: Vitamin B12 Necessary for Arterial Health (http://nutritionfacts.org/video/vitamin-b12-necessary-for-arterial-health/). Cholesterol may do more than just impair the function of our arteries. Check out the images in my video Cholesterol Crystals May Tear Through Our Artery Lining (http://nutritionfacts.org/video/cholesterol-crystals-may-tear-though-our-artery-lining/). But isn’t there like small, dense cholesterol particles and large fluffy ones? See Does Cholesterol Size Matter? (http://nutritionfacts.org/video/Does-Cholesterol-Size-Matter). There are three things that increase our cholesterol level: Trans Fat, Saturated Fat, and Cholesterol: Tolerable Upper Intake of Zero (http://nutritionfacts.org/video/trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero/). What about moderation? Well, how moderate do you want your disease? See Everything in Moderation? Even Heart Disease? (http://nutritionfacts.org/video/everything-in-moderation-even-heart-disease). Have a question for Dr. Greger about this video? Leave it in the comment section at http://nutritionfacts.org/video/plant-based-treatment-for-angina and he'll try to answer it! Image Credit: OpenClipartVectors via Pixabay. https://NutritionFacts.org • Subscribe: https://nutritionfacts.org/subscribe • Donate: https://nutritionfacts.org/donate • Podcast : https://nutritionfacts.org/audio • Facebook: www.facebook.com/NutritionFacts.org • Twitter: www.twitter.com/nutrition_facts • Instagram: www.instagram.com/nutrition_facts_org • Books (including the NEW How Not to Diet Cookbook): https://nutritionfacts.org/books • Shop: https://drgreger.org

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