2016

With monumental events unfolding before our eyes and the attack of Iran on Israel, are we watching ancient prophecies being fulfilled? Are these part of God...

Bob Amsterdam is an international human rights lawyer who’s been banned from Russia by Vladimir Putin. He says Ukraine is the single most repressive country he’s ever been to, a place where everyone’s

Order _The Temple Revealed_ by Dr. Christian Widener here: https://amzn.to/3IZH3tmUncover The Prophetic Secret To Unraveling 3000 Years Of Temple Mount Histo...

Do you suffer from diabetic neuropathy, chemo-induced neuropathy, or HIV neuropathy? Join our clinical trials. Subscribe for updates and information on clinical trials.

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱As many of you ...

What is celiac disease and how does it cause nerve damage? Learn more: https://winsantor.com/nerve-damage-and-celiac-disease-the-hidden-connection/Visit our ...

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Distal symmetric diabetic peripheral polyneuropathy (DPN) is the most common form of neuropathy in the world, affecting 30 to 50% of diabetic individuals and resulting in significant morbidity and socioeconomic costs. This review summarizes updates in ...

Diabetic nephropathy (DN) is a common microvascular complication of diabetes. Fucoidan, a polysaccharide containing fucose and sulfate group, ameliorates DN. However, the underlying mechanism has not been fully understood. This study aimed to explore the effects and mechanism of fucoidan on DN in high-fat diet-induced diabetic mice. A total of 90 C57BL/6J mice were randomly assigned to six groups (n = 15) as follows: normal control (NC), diabetes mellitus (DM), metformin (MTF), low-dose fucoidan (LFC), medium-dose fucoidan (MFC), and high-dose fucoidan (HFC). A technique based on fluorescein isothiocyanate (FITC-sinistin) elimination kinetics measured percutaneously was applied to determine the glomerular filtration rate (GFR). After 24 weeks, the mice were sacrificed and an early stage DN model was confirmed by GFR hyperfiltration, elevated urinary creatinine, normal urinary albumin, tubulointerstitial fibrosis, and glomerular hypertrophy. Fucoidan significantly improved the GFR hyperfiltration and renal fibrosis. An enriched SCFAs-producing bacteria and increased acetic concentration in cecum contents were found in fucoidan groups, as well as increased renal ATP levels and improved mitochondrial dysfunction. The renal inflammation and fibrosis were ameliorated through inhibiting the MAPKs pathway. In conclusion, fucoidan improved early stage DN targeting the microbiota–mitochondria axis by ameliorating mitochondrial oxidative stress and inhibiting the MAPKs pathway.

Explore our GMO-free natural vitamin supplements, healthy seeds with vitamin B17, and organic wellness solutions for your well-being ✅

Watch as Dr Ardis interviews the President of Richardson Nutritional Center President, John A. Richardson, Jr. about the power of Laetrile and the legacy of his father, Dr. John A. Richardson, MD, who

(NaturalHealth365) Over 3 million Americans suffer from atrial fibrillation, or irregular heartbeat. Diet soda consumption may play a role.

The Shroud of Turin is the most investigated artifact in world history. Does the burial cloth of Jesus provide evidence of His resurrection? Did Jesus leave ...

Trehalose, a remarkable substance, holds great importance in biomedicine for its anti-inflammatory properties and its capacity to hinder scar formatio…

It is widely acknowledged that dietary habits have profound impacts on human health and diseases. As the most important sweeteners and energy sources …

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Thioredoxin-interacting protein (TXNIP) is an important regulatory protein for thioredoxin (TRX) that elicits the generation of reactive oxygen species (ROS) by inhibiting the redox function of TRX...

It seems as if there is no limit to the various body systems that are now being characterized as having a unique association with bacteria and other resident living organisms. …

In this podcast episode, Dr. Ardis explores the health benefits of taurine supplements and how they have been misrepresented in the medical field. He discusses the importance of taurine for various as

Supplement Facts & Directions Supplement Facts Serving Size: 800 milligrams Servings Per Container: Varies Amount Per Serving % Daily Value* Taurine 800 mg † * Percent Daily Values are based on a 2,000 calorie diet.† Daily Value Not Established ‡ These supplement facts may vary from the product you receive. Please call for exact numbers. Other Ingredients: None Contains: Free of: Sugar, Soy, Dairy, Yeast, Gluten, Corn & Additives. Directions: As a dietary supplement, take 800 mg (3/16 tsp) up to two times daily, or as directed by a physician. Accurate gram weight scale recommended. Warning: If you are pregnant, nursing, taking any medications or have any medical condition consult your physician before use. Keep out of reach of children. Store in a cool, dark & dry place. Product Details Did You Know? The word taurine comes from the Latin

Unleash the potential of your daily regimen with our pristine BulkSupplements.com Taurine powder. Pure, high-quality, fine powder for seamless mixing, it's the perfect addition to beverages or pre-workout shakes. Fuel your day with a serving of excellence – energizing your ambitions, one serving at a time. Get ready to power through!

Joel Richardson closes out his teaching on Revelation 19 in a bonus session covering Islamic Eschatology and how it relates to the Book of Revelation in THE ...

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱In a groundbrea...

Fibroblast growth factor 21 (FGF21) plays a crucial role in metabolism and brain function. Glucosamine (GLN) has been recognized for its diverse beneficial effects. This study aimed to elucidate the modulation of FGF21 production by GLN and its impact on learning and memory functions. Using both in vivo and in vitro models, we investigated the effects of GLN on mice fed with a normal diet or high-fat diet and on mouse HT22 hippocampal cells, STHdhQ7/Q7 striatal cells, and rat primary cortical neurons challenged with GLN. Our results indicated that GLN promotes learning and memory functions in mice and upregulates FGF21 expression in the hippocampus, cortex, and striatum, as well as in HT22 cells, STHdhQ7/Q7 cells, and cortical neurons. In animals receiving GLN together with an FGF21 receptor FGFR1 inhibitor (PD173074), the GLN-enhanced learning and memory functions and induction of FGF21 production in the hippocampus were significantly attenuated. While exploring the underlying molecular mechanisms, the potential involvement of NF-κB, Akt, p38, JNK, PKA, and PPARα in HT22 and NF-κB, Akt, p38, and PPARα in STHdhQ7/Q7 were noted; GLN was able to mediate the activation of p65, Akt, p38, and CREB in HT22 and p65, Akt, and p38 in STHdhQ7/Q7 cells. Our accumulated findings suggest that GLN may increase learning and memory functions by inducing FGF21 production in the brain. This induction appears to be mediated, at least in part, through GLN’s activation of the NF-κB, Akt, p38, and PKA/CREB pathways.

Natural rare sugars are an alternative category of sweeteners with positive physiologic and metabolic effects both in in vitro and animal models. D-allulose is a D-fructose epimer that combines 70% sucrose sweetness with the advantage of an extremely low energy content. However, there are no data about the effect of D-allulose against adipose dysfunction; thus, it remains to be confirmed whether D-allulose is useful in the prevention and in treatment of adipose tissue alterations. With this aim, we evaluated D-allulose’s preventive effects on lipid accumulation in 3T3-L1 murine adipocytes exposed to palmitic acid (PA), a trigger for hypertrophic adipocytes. D-allulose in place of glucose prevented adipocyte hypertrophy and the activation of adipogenic markers C/EBP-β and PPARγ induced by high PA concentrations. Additionally, D-allulose pretreatment inhibited the NF-κB pathway and endoplasmic reticulum stress caused by PA, through activation of the Nrf2 pathway. Interestingly, these effects were also observed as D-allulose post PA treatment. Although our data need to be confirmed through in vivo models, our findings suggest that incorporating D-allulose as a glucose substitute in the diet might have a protective role in adipocyte function and support a unique mechanism of action in this sugar as a preventive or therapeutic compound against PA lipotoxicity through the modulation of pathways connected to lipid transport and metabolism.

Learn about your kidneys, how to protect them, and what to eat when you have kidney disease! Dr. Sean Hashmi is a Board Certified Nephrologist and Michele Crosmer is a Registered Dietitian and Certified Specialist in Renal Nutrition. We hope to educate and empower you to take control of your health and make proactive lifestyle choices to protect kidney health! Thanks so much for subscribing to our channel! Sean Hashmi, MD, MS, FASN and Michele Crosmer, RD, CSR

Hello, dear friends! I'm Dr. Sean Hashmi, founder of SELF Principle, a community focused on the latest research in nutrition, longevity, health, wellness, and kidney disease. As a father, husband, and kidney disease specialist, my journey in medicine began with personal loss and my family's health struggles. These experiences ignited my passion to explore the healing power of nutrition and wellness. Here, we'll delve into scientific insights, engaging expert interviews, and real stories. More than just learning, this channel is about connecting, growing, and supporting one another on the path to better health. Your thoughts, challenges, and triumphs matter to me, so please SUBSCRIBE and join our VIP list by hitting the bell. Together, we'll embark on a journey toward understanding, compassion, and wellness. With heartfelt gratitude, Sean Hashmi, MD, MS, FASN

Many have abandoned the media’s desperate attempt to ignore why cancer rates are spiking. Now, the American Cancer Society is sounding the alarm, predicting an 80% increase in tumors by 2050. Meanwhile, independent researchers have stepped up and honed in on credible sources pointing to the mass COVID vaccine rollout in 2021 as the prime […]

In this podcast episode, Dr. Ardis explores the controversial topic of nicotine, challenging commonly held beliefs about its addictiveness and highlighting its potential benefits for health. He discus