2016

There has been scholarly debate over the destruction of the city of Jericho, and different conclusions on if it happened when the Bible says it does, or not....

How locally resolving the cell danger response allows chronically impaired tissues to heal and resume their normal function

The Architecture of Global Emergency Rule Was Activated in One Week. - Part 4 in a Series

Shared via Copilot

How the Epstein Files Reveal the Architecture Behind Censorship, Crisis Finance, and What Happened When I Investigated It - Part 3 in a Series

Background Acetaminophen overdose is a leading cause of drug-induced acute liver damage, underscoring the urgent need for accessible hepatoprotective therapies. This study evaluated the hepatoprotective effects of Aqueous Aloe vera gel extract on acetaminophen-induced liver damage in adult male Albino Wistar rats. Methodology Liver Damage was induced in Albino Wistar rats by oral administration of acetaminophen (750 mg/kg). The rats were divided into six groups: normal control, negative control, positive control (silymarin 50 mg/kg), and three treatment groups receiving Aloe vera gel extract at doses of 250 mg/kg, 500 mg/kg, and 1000 mg/kg. Body and liver weight, hematological, biochemical and oxidative stress parameters and liver histology were assessed after 7 days of treatment. Results Treatment with Aloe vera gel extract demonstrated dose-dependent hepatoprotective, anti-inflammatory and antioxidant effects with the 1000 mg/kg dose exhibiting efficacy comparable to silymarin. Higher doses (1000 mg/kg) significantly increase both the body weight and weight of the liver (p = 0.0265 and p = 0.0061); decreased the white blood cell count (p = 0.0034) and also improved hematological parameters. The extract at 1000 mg/kg also enhanced antioxidant status by reducing MDA levels (p < 0.0001) while increasing SOD (p < 0.0001) and catalase activities. Histological examination also showed that higher doses of the aqueous Aloe vera gel extract restored liver histoarchitecture, with clearly defined nuclei and cell borders. Conclusion This study demonstrates that the aqueous Aloe vera gel extract mitigates acetaminophen-induced hepatotoxicity through antioxidant, anti-inflammatory, and regenerative mechanisms. At 1000 mg/kg, it restored hepatic histoarchitecture, haematological homeostasis, normalized liver function biomarkers, and suppressed oxidative stress, rivalling silymarin in efficacy. The observed improvements in liver histology, haematological parameters, and antioxidant biomarkers indicate Aloe vera’s therapeutic potential, likely mediated through its bioactive constituents with antioxidant and anti-inflammatory properties. Further research is recommended to understand its mechanism of action, long-term and potential clinical applications.

In this episode 5, Dr. Bill Salus reveals how the Arab-Israeli conflict concludes before the Seven-Year Tribulation Period commences. He reveals how the bloo...

Harvard. Stanford. McLean. The Published Remissions, the Double-Blind Trials, and the Media's Refusal to Look.

What Everyone Needs to Know About "Antidepressants"

The Exact conflict Jesus warned us about is happening now. Jesus gave a specific prophecy about the beginning of the end and the birth pains, referencing His...

Many children with attention, learning, language, or behavioral challenges may not be getting enough usable folate into their brain, even when their blood le...

Dr. McCullough on stage at Lance Wallnau's Health & Wellness Summit, Trump Doral, Miami

Biosecurity as Governance, and the Quiet Erosion of Sovereignty - PART II of a Series

Obesity remains a significant public health concern, with recent studies revealing that the detrimental health effects often persist even in individuals who have successfully shed excess weight. D-allulose, a low-calorie monosaccharide, has shown potential in promoting weight loss and reducing chronic inflammation associated with metabolic disorders. However, it is still unclear whether D-allulose has long-term benefits once intake is stopped. This study examined the prolonged effects of D-allulose on obesity and metaflammation. Our findings demonstrated that obese mice treated with D-allulose for one month maintained significantly lower lipid accumulation, fasting blood glucose level, glycosylated protein levels, and reduced adipose tissue inflammation compared to the Model group, even 75 days after cessation of D-allulose intake. Further cellular analyses revealed that D-allulose attenuated the activation and expression of TLR4/MyD88/NFB pathway in macrophages triggered by inflammatory stimuli. Additionally, D-allulose administration was associated with reduced protein lactylation levels in macrophages, suggesting that D-allulose may exert lasting benefits through epigenetic regulation mechanisms. These results underscore the sustained efficacy of D-allulose in combating fat accumulation, blood glucose, and inflammation, presenting a promising therapeutic approach for mitigating the residual adverse effects of obesity in individuals who have achieved weight loss.

Jesus explicitly commanded his followers to understand only one specific bible prophecy. Why did he single this one out? This Nelson Walters video explores ...

We report the longest documented persistence of mRNA vaccine components to date, independently confirmed across multiple laboratories, biospecimens, and time points using diverse analytical methods.

Inside the JPMorgan–Gates–Epstein Pipeline: Donor-Advised Funds, Vaccine Finance, and the Architecture of Pre-Positioned Profit

How maladaptive and harmful signaling within the body causes complex chronic illnesses

Understanding the Cell Danger Response is critical for treating treating spike protein injuries and many other complex illnesses.

Dr. Sircus shares how cyclodextrins helped reverse severe arterial blockages after he was scheduled for emergency stents.Watch the first 3 minutes and 40 sec...

The greatest mystery in the Book of Revelation is a "beast that was, is not, and is about to come up out of the Bottomless Pit." Is this also the Little Horn...

When Judah was diagnosed with cancer at 6 years old, his family quickly discovered that “choice” in pediatric oncology is largely an illusion.

Florida testing found SweeTarts, Snickers, Skittles, Kit Kat, Nerds, Sour Patch Kids, Twizzlers, Jolly Ranchers, Trolli, and Tootsie Roll among the worst offenders.

What Jared Kushner is now doing may provoke the anger of God!We looked deeper into his Gaza plans and his role within the Board of Peace.. And what they are...

A New Randomized Trial Says Yes. For decades, patients with atrial fibrillation (AF) have been told that caffeine is a trigger for arrhythmias. Many clinicians have reinforced this idea, urging …

This overlooked prophecy from the Book of Daniel may be the next thing on God's prophetic timeline. This Nelson Walters video explores the prophecy in Daniel...

Dietary vitamin C rapidly enters skin tissue and improves structural density and epidermal renewal within 8 weeks.

Actor Chris Pratt has some powerful perspectives on God and artificial intelligence. Billy Hallowell and Raj Nair break down his thought-provoking statements...

Why do some people keep getting sick with lingering colds, flu, and chronic infections? In this episode, we break down the real causes of immune system break...