Biome

In this podcast episode, Dr. Henry Ealy and Dr. Brian Ardis discuss the impact of food allergies on health. Dr. Ealy shares his personal experience with delayed food allergies and the surprising resul

It seems as if there is no limit to the various body systems that are now being characterized as having a unique association with bacteria and other resident living organisms. …

(NaturalHealth365) Is chronic fatigue syndrome triggered by a leaky gut? Researchers found a connection between the gut and chronic fatigue.

Are you tired of being constantly interrupted during your precious sleep by those annoying trips to the bathroom? Well, you're not alone! In this video, we'r...

Recent advances in sequencing techniques unveiled the vast potential of ribosomally synthesized and post-translationally modified peptides (RiPPs) encoded in microbiomes. Class I lantibiotics such as nisin A, widely used as a food preservative, have been investigated for their efficacy in killing pathogens. However, the impact of nisin and nisin-like class I lantibiotics on commensal bacteria residing in the human gut remains unclear. Here, we report six gut-derived class I lantibiotics that are close homologues of nisin, four of which are novel. We applied an improved lantibiotic expression platform to produce and purify these lantibiotics for antimicrobial assays. We determined their minimal inhibitory concentration (MIC) against both Gram-positive human pathogens and gut commensals and profiled the lantibiotic resistance genes in these pathogens and commensals. Structure–activity relationship (SAR) studies with analogs revealed key regions and residues that impact their antimicrobial properties. Our characterization and SAR studies of nisin-like lantibiotics against both pathogens and human gut commensals could shed light on the future development of lantibiotic-based therapeutics and food preservatives.

The highly post-translationally modified peptide nisin has been studied over the course of the last 100 years, and although it has been employed successfully as

(NaturalHealth365) Discover the findings of a recent study published in ACS Chemical Biology about the dangers of a common food preservative.

(NaturalHealth365) Research reveals that poor gut health can increase the threat of breast cancer. Find out the role of the gut microbiome.

DuckDuckGo. Privacy, Simplified.

The application of next generation sequencing techniques has allowed the characterization of the urinary tract microbiome and has led to the rejection of the pre-established concept of sterility in the urinary bladder. Not only have microbial communities in the urinary tract been implicated in the maintenance of health but alterations in their composition have also been associated with different urinary pathologies, such as urinary tract infections (UTI). Therefore, the study of the urinary microbiome in healthy individuals, as well as its involvement in disease through the proliferation of opportunistic pathogens, could open a potential field of study, leading to new insights into prevention, diagnosis and treatment strategies for urinary pathologies. In this review we present an overview of the current state of knowledge about the urinary microbiome in health and disease, as well as its involvement in the development of new therapeutic strategies.

(NaturalHealth365) Increasing antibiotic resistance leads to deaths due to neonatal and pediatric infections globally.

Cardiovascular disease (CVD) is the leading cause of death worldwide. The human body is populated by a diverse community of microbes, dominated by bacteria, but also including viruses and fungi. The largest and most complex of these communities is located in the gastrointestinal system and, with its associated genome, is known as the gut microbiome. Gut microbiome perturbations and related dysbiosis have been implicated in the progression and pathogenesis of CVD, including atherosclerosis, hypertension, and heart failure. Although there have been advances in the characterization and analysis of the gut microbiota and associated bacterial metabolites, the exact mechanisms through which they exert their action are not well understood. This review will focus on the role of the gut microbiome and associated functional components in the development and progression of atherosclerosis. Potential treatments to alter the gut microbiome to prevent or treat atherosclerosis and CVD are also discussed.

(NaturalHealth365) Scientists believe delayed gut microbiota maturation is responsible for childhood allergies.

Founded by a chronic UTI sufferer, Uqora makes UTI relief products and proactive urinary tract health supplements that work. Try Uqora risk-free today!

There are some foods you can cut around the mold, while others may make you sick; here are some tips for how to reduce mold growth on your food.

Looking to treat your candida with diet? Follow my candida diet guidelines and you're sure to not only feel better and healthier, but also be candida-free.

Significant interest in recent years has focused on gut microbiota-host interaction because accumulating evidence has revealed that intestinal microbiota play an important role in human health and disease, including cardiovascular diseases. Changes in ...

Founded by a chronic UTI sufferer, Uqora makes UTI relief products and proactive urinary tract health supplements that work. Try Uqora risk-free today!

DuckDuckGo. Privacy, Simplified.

Berberine's potential health benefits include regulating blood sugar, lowering cholesterol and weight management. Learn about the dosage and side effects.

2016 Interview If you're not optimally healthy, could candida be at fault? In this interview, British osteopath and naturopath, Dr. Leon Chaitow, author of "Candida Albicans: Natural Remedies for Yeast Infection," discusses its dangers — and more i…

Chronic bladder infection can be a painful, frustrating problem. Learn about causes and treatments.

Urinary tract infections (UTIs) are frequent in humans, affecting the upper and lower urinary tract. Present diagnosis relies on the positive culture of uropathogenic bacteria from urine and clinical markers of inflammation of the urinary tract. The bladder is constantly challenged by adverse environmental stimuli which influence urinary tract physiology, contributing to a dysbiotic environment. Simultaneously, pathogens are primed by environmental stressors such as antibiotics, favoring recurrent UTIs (rUTIs), resulting in chronic illness. Due to different confounders for UTI onset, a greater understanding of the fundamental environmental mechanisms and microbial ecology of the human urinary tract is required. Such advancements could promote the tandem translation of bench and computational studies for precision treatments and clinical management of UTIs. Therefore, there is an urgent need to understand the ecological interactions of the human urogenital microbial communities which precede rUTIs. This review aims to outline the mechanistic aspects of rUTI ecology underlying dysbiosis between both the human microbiome and host physiology which predisposes humans to rUTIs. By assessing the applications of next generation and systems level methods, we also recommend novel approaches to elucidate the systemic consequences of rUTIs which requires an integrated approach for successful treatment. To this end, we will provide an outlook towards the so-called ‘uncomplicated enviro...

The recurrence of the urinary tract infections (UTI), following the antibiotic treatments suggests the pathogen’s resistance to conventional antibiotics. This calls for the exploration of an alternative therapy.The anti-uropathogenic and bactericidal ...

We use a lot of antibiotics. For coughs, cuts, urinary tract infections, and many times “just in case.”

Caprylic acid from coconuts is a beneficial saturated fatty acid that has antibacterial, antiviral, antifungal and anti-inflammatory properties.