Biome

Tools for ending the silent epidemic of constipation

August's Open Thread

(NaturalHealth365) New study reveals how common prescription drugs wipe out protective gut bacteria, damaging our health.

Follow for more: https://www.instagram.com/drbenlynch/When is the best time to take probiotics? Dr. Ben Lynch is a bestselling author (Dirty Genes), a natur...

You’ve heard your gut changes your brain. Here are the key pathways!

(NaturalHealth365) Multiple studies reveal common food chemicals in processed foods may cause Crohn's disease, cancer, and gut inflammation.

Gastroenterologist and microbiome expert Dr. Sabine Hazan reveals that many commercial yogurts and probiotics don’t contain the gut-healthy strains they claim, raising major concerns about the yogurt and supplement industry standards. Her cutting-edge research links gut health to chronic disease and vaccine response, pointing to the microbiome as a critical—yet overlooked—piece of the medical puzzle. […]

What if tiny viruses are doing more than just invading your body—what if they're actually protecting you? In this groundbreaking presentation, microbiologist...

The overuse of antibiotics is a widespread problem within conventional medicine. Discover how these drugs can cause serious health issues.

(NaturalHealth365) Poor digestion and bad stomach bacteria have been scientifically shown to cause mental and physical illness.

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(NaturalHealth365) The excessive use of antibiotics must stop. Too many physicians are prescribing them for the wrong reasons.

Originally developed and commercialized as an antiprotozoal agent, nitazoxanide was later identified as a first-in-class broad-spectrum antiviral drug and has been repurposed for the treatment of influenza. A Phase 2b/3 clinical trial recently published ...

In this podcast episode, Dr. Henry Ealy and Dr. Brian Ardis discuss the impact of food allergies on health. Dr. Ealy shares his personal experience with delayed food allergies and the surprising resul

It seems as if there is no limit to the various body systems that are now being characterized as having a unique association with bacteria and other resident living organisms. …

(NaturalHealth365) Is chronic fatigue syndrome triggered by a leaky gut? Researchers found a connection between the gut and chronic fatigue.

Are you tired of being constantly interrupted during your precious sleep by those annoying trips to the bathroom? Well, you're not alone! In this video, we'r...

(NaturalHealth365) Discover the findings of a recent study published in ACS Chemical Biology about the dangers of a common food preservative.

Recent advances in sequencing techniques unveiled the vast potential of ribosomally synthesized and post-translationally modified peptides (RiPPs) encoded in microbiomes. Class I lantibiotics such as nisin A, widely used as a food preservative, have been investigated for their efficacy in killing pathogens. However, the impact of nisin and nisin-like class I lantibiotics on commensal bacteria residing in the human gut remains unclear. Here, we report six gut-derived class I lantibiotics that are close homologues of nisin, four of which are novel. We applied an improved lantibiotic expression platform to produce and purify these lantibiotics for antimicrobial assays. We determined their minimal inhibitory concentration (MIC) against both Gram-positive human pathogens and gut commensals and profiled the lantibiotic resistance genes in these pathogens and commensals. Structure–activity relationship (SAR) studies with analogs revealed key regions and residues that impact their antimicrobial properties. Our characterization and SAR studies of nisin-like lantibiotics against both pathogens and human gut commensals could shed light on the future development of lantibiotic-based therapeutics and food preservatives.

The highly post-translationally modified peptide nisin has been studied over the course of the last 100 years, and although it has been employed successfully as

(NaturalHealth365) Research reveals that poor gut health can increase the threat of breast cancer. Find out the role of the gut microbiome.

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The application of next generation sequencing techniques has allowed the characterization of the urinary tract microbiome and has led to the rejection of the pre-established concept of sterility in the urinary bladder. Not only have microbial communities in the urinary tract been implicated in the maintenance of health but alterations in their composition have also been associated with different urinary pathologies, such as urinary tract infections (UTI). Therefore, the study of the urinary microbiome in healthy individuals, as well as its involvement in disease through the proliferation of opportunistic pathogens, could open a potential field of study, leading to new insights into prevention, diagnosis and treatment strategies for urinary pathologies. In this review we present an overview of the current state of knowledge about the urinary microbiome in health and disease, as well as its involvement in the development of new therapeutic strategies.

(NaturalHealth365) Increasing antibiotic resistance leads to deaths due to neonatal and pediatric infections globally.

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative motor neuron disease accompanied by both systemic and central nervous system–specific…