Allulose

Allulose, a rare sugar, has gained significant attention in recent years due to its numerous health benefits, primarily concerning metabolic health. To be sure, it seems like it is everywhere …

Obesity remains a significant public health concern, with recent studies revealing that the detrimental health effects often persist even in individuals who have successfully shed excess weight. D-allulose, a low-calorie monosaccharide, has shown potential in promoting weight loss and reducing chronic inflammation associated with metabolic disorders. However, it is still unclear whether D-allulose has long-term benefits once intake is stopped. This study examined the prolonged effects of D-allulose on obesity and metaflammation. Our findings demonstrated that obese mice treated with D-allulose for one month maintained significantly lower lipid accumulation, fasting blood glucose level, glycosylated protein levels, and reduced adipose tissue inflammation compared to the Model group, even 75 days after cessation of D-allulose intake. Further cellular analyses revealed that D-allulose attenuated the activation and expression of TLR4/MyD88/NFB pathway in macrophages triggered by inflammatory stimuli. Additionally, D-allulose administration was associated with reduced protein lactylation levels in macrophages, suggesting that D-allulose may exert lasting benefits through epigenetic regulation mechanisms. These results underscore the sustained efficacy of D-allulose in combating fat accumulation, blood glucose, and inflammation, presenting a promising therapeutic approach for mitigating the residual adverse effects of obesity in individuals who have achieved weight loss.

Allulose, a rare sugar, has gained significant attention in recent years due to its numerous health benefits, primarily concerning metabolic health. To be sure, it seems like it is everywhere …

Allulose, a rare sugar, has gained significant attention in recent years due to its numerous health benefits, primarily concerning metabolic health. To be sure, it seems like it is everywhere …

Allulose, a rare sugar, has gained significant attention in recent years due to its numerous health benefits, primarily concerning metabolic health. To be sure, it seems like it is everywhere …

Allulose, a rare sugar, has gained significant attention in recent years due to its numerous health benefits, primarily concerning metabolic health. To be sure, it seems like it is everywhere …

Allulose, a rare sugar, has gained significant attention in recent years due to its numerous health benefits, primarily concerning metabolic health. To be sure, it seems like it is everywhere …

Allulose, a rare sugar, has gained significant attention in recent years due to its numerous health benefits, primarily concerning metabolic health. To be sure, it seems like it is everywhere …

Allulose, a rare sugar, has gained significant attention in recent years due to its numerous health benefits, primarily concerning metabolic health. To be sure, it seems like it is everywhere …

Allulose, a rare sugar, has gained significant attention in recent years due to its numerous health benefits, primarily concerning metabolic health. To be sure, it seems like it is everywhere …

Allulose, a rare sugar, has gained significant attention in recent years due to its numerous health benefits, primarily concerning metabolic health. To be sure, it seems like it is everywhere …

Allulose, a rare sugar, has gained significant attention in recent years due to its numerous health benefits, primarily concerning metabolic health. To be sure, it seems like it is everywhere …

Allulose, a rare sugar, has gained significant attention in recent years due to its numerous health benefits, primarily concerning metabolic health. To be sure, it seems like it is everywhere …

Allulose, a rare sugar, has gained significant attention in recent years due to its numerous health benefits, primarily concerning metabolic health. To be sure, it seems like it is everywhere …

D-allulose is a rare monosaccharide with established safety and documented biological functions, whereas its potential effects on ulcerative colitis r…

Allulose, a rare sugar, has gained significant attention in recent years due to its numerous health benefits, primarily concerning metabolic health. To be sure, it seems like it is everywhere …

Excessive sugar intake has fueled global obesity, diabetes, and cardiovascular burdens, driving demand for natural sugar substitutes. Yet, their safet…

The acute effect of D-allulose consumption on postprandial glycaemia and insulin secretion in healthy individuals - Volume 84 Issue OCE4

This study investigated the anti-obesity and anti-inflammatory effects of D-Allulose compared to erythritol in high-fat diet (HFD)-fed mice, focusing …

Fructose and Metabolic SyndromeCell Metabolism: https://pubmed.ncbi.nlm.nih.gov/32502381/ Fructose, intracellular pathwayJ. Biol Chem: https://pubmed.ncbi.nl...

We have clearly entered a new era when mainstream science has come to embrace the notion that nutrition exerts significant influence over various physiological functions, including immune regulation, and may …

Allulose is on the top of my sweetener preference list for both objective and subjective reasons.

D-Allulose, a rare sugar and C3-epimer of D-fructose has been proposed as a candidate for dietary restriction mimetics via inhibition of glycolysis. Anti-hyperglycemic and anti-obesity effects have been reported in rodents and human subjects. Here, ...

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D-allulose, a rare sugar recognized as Generally Recognized as Safe, has emerged as a potential alternative to sucrose. Despite its growing popularity…

D-Allulose has blood glucose suppression effects in both animal and clinical studies. The mechanism mediating glucose suppression in animals is contro …