Amino Acids

For selection of phospholipid excipients for pharmaceutical formulations, natural phospholipids are preferred compared to synthetic phospholipids because they are available at large scale with reprod...

Editor's note: This post was originally published in August 2016. It has been updated and republished in February 2019. What is glutathione? It may be the most important molecule you need to stay healthy and prevent disease. It's known for its anti-aging power as well as its benefit in fighting cancer, heart disease, dementia, and other chronic diseases. It's also important for treating everything from autism and Alzheimer's disease and more. What is Glutathione and What Does it Do? Glutathione is a combination of three simple building blocks of protein or amino acids − cysteine, glycine, and glutamine − and is

Inhibitory effects of trehalose liposomes (DMTre) composed of 30mol% l-α-dimyristoylphosphatidylcholine (DMPC) and 70mol% trehalose surfactants on the growth of lymphoblastic leukemia (MOLT-4) cells in vitro and therapeutic effects of DMTre for xenograft mice model of carcinoma in vivo were examined …

Inhibitory effects of trehalose liposomes (DMTre) composed of 30mol% l-α-dimyristoylphosphatidylcholine (DMPC) and 70mol% trehalose surfactants on the growth of lymphoblastic leukemia (MOLT-4) cells in vitro and therapeutic effects of DMTre for xenograft mice model of carcinoma in vivo were examined …

Glutathione is amazing. Ever the underdog, few people have heard of this molecule, yet it supports nearly every aspect of our health. Consider these incredible properties: By acting as an antioxidant, it prevents wear and tear on your tissues, helping you stay youthful, age gracefully, and remain free of chronic diseases. By supporting every-day detoxification, it does …

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Background/Aim: Previous evidence demonstrates that trehalose liposomes (DMTreC14) composed of L-α-dimyristoylphosphatidylcholine (DMPC) and α-D-glycopyranosyl-α-D-glucopyranoside monomyristate (TreC14) inhibit proliferation and invasion on lung carcinoma (A549 cells) in vitro. Here, we aimed to investigate suppressive effects of DMTreC14 on the growth of tumor on human lung carcinoma bearing mice. Materials and Methods: DMTreC14 composed of 30 mol% DMPC and 70 mol% TreC14 were prepared by the sonication method. Anti-tumor activities of DMTreC14 using the subcutaneous and orthotopic graft-bearing mice of A549 cells were investigated in vivo. Results: The remarkable reduction of volume and weight in subcutaneous tumors on subcutaneous lung carcinoma-bearing mice topically administrated with DMTreC14 were obtained. Apoptotic-positive cells in the subcutaneous tumor slice of subcutaneous lung carcinoma-bearing mice topically administrated with DMTreC14 were observed using TUNEL staining. Lung weights on the orthotopic graft-bearing mice of lung carcinoma intravenously administrated with DMTreC14 were markedly decreased compared to those of the control group. Remarkable decrease in dimensions of tumor area of lung on the orthotopic graft-bearing mice of lung carcinoma intravenously administrated with DMTreC14 was obtained in histological analysis using the hematoxylin and eosin staining. Conclusion: Remarkably high anti-tumor activities of DMTreC14 for the subcutaneous and orthotopic graft-bearing mice of lung carcinoma accompanied with apoptosis were revealed for the first time in vivo.

Colostrum powder dressings are safe, promoter of wound healing, more patient compliance in terms of less pain, less number of dressing required. This treatment though found to be more expensive than conventional dressings; results indicate that colostrum powder dressings may be used as an adjunct in …

Deep wounds are extending deeper, across deep fascia into muscles or deeper structures. Understanding of nutrition, immunology, psychological issues, the physiology and the metabolic interactions require for optimal treatment of deep wounds. Wound dressing ...

Reduced glutathione or simply glutathione (γ-glutamylcysteinylglycine; GSH) is found in the cytosol of most cells of the body. GSH in the epithelial lining fluid (ELF) of the lower respiratory tract is thought to be the first line of defense against ...

A team of researchers performed experiments on blood-deprived cells that were subsequently exposed to blood serum. Remarkably, all the cells started to move and grow in the same direction as soon as the blood serum was added.

Collagen (CO)/chitosan-glucan complex (CSGC) hollow fibers encapsulated aloe vera (AV) dressing scaffold (CO/CSGC@AV) were fabricated for the first ti…

Learn more about GLUTATHIONE uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain GLUTATHIONE.

No significant better results in terms of completeness of healing of burn and chronic wounds between collagen dressing and conventional dressing were found. Collagen dressing, however, may avoid the need of skin grafting, and provides additional advantage of patients' compliance and comfort.

*** Our collagen, made of ONE simple ingredient is a dietary supplement with a beneficial combination of amino acids. At Great Lakes Gelatin Company, we believe that a healthy lifestyle and a balanced diet including collagen, is the cornerstone to a life well-lived. Collagen is nearly tasteless, colorless, and odorless, and it is easily digested. It will not congeal in cold liquids making it a perfect addition to cold and hot beverages, smoothies or recipes. Just mix in and enjoy!   Ingredients: Bovine Collagen Hydrolysate Collagen Types 1 & 3   Grass-Fed & Pasture-Raised, Kosher, Paleo-Friendly, Keto-Certified *** Using a tablespoon or scoop, add 2 tablespoons of Collagen Hydrolysate and pour slowly into your beverage of choice. Stir until dissolved. Hot liquids will dissolve the collagen more quickly, while colder liquids will take a bit longer. Once the collagen is dissolved, enjoy your collagen-packed drink! Many customers enjoy adding collagen to: Coffee Tea Smoothies Oatmeal Yogurt Orange juice Water (with or without a lemon slice) Soup For more ideas visit our Recipes Page!

Click here to subscribe - https://www.glutenfreesociety.org/wxrn My favorite NAC Supplement - https://bit.ly/32piGPB L-Glutamine Supplement - https://bit.ly/2q6bZmi Virid - https://bit.ly/2U1gY4Q For viral outbreaks, including coronavirus, many people are taking supplements to support their immune systems. Vitamin C, zinc, vitamin D, vitamin A, and elderberry are all effective support strategies, but one of the most ignored yet potent strategies come in the form of viral fighting amino acids. The top amino acids to support immune function include NAC, AKA N-Acetyl-Cysteine, and L-glutamine. To connect with Dr. Osborne visit: On the web: https://drpeterosborne.com/ Facebook: https://www.facebook.com/DoctorPeterO... Pinterest: https://www.pinterest.com/docosborne/ Instagram: https://www.instagram.com/drosborne Twitter: https://twitter.com/glutenology *These statements have not been evaluated by the Food and Drug Administration. This video is not intended to diagnose, treat, cure or prevent any disease. It is strictly intended for educational purposes only. Additionally, this information is not intended to replace the advice of your physician. Dr. Osborne is not a medical doctor. He does not treat or diagnose disease. He offers nutritional support to people seeking an alternative from traditional medicine. Dr. Osborne is licensed with the Pastoral Medical Association.

Glutathione supplements may offer some health benefits from their antioxidant content. But be aware glutathione side effects can result from improper use.

Protein supplementation in combination with resistance training may increase muscle mass and muscle strength in elderly subjects. The objective of this study was to assess the influence of post-exercise protein supplementation with collagen peptides v. placebo on muscle mass and muscle function foll …

Dysfunction of the intestinal barrier plays a key role in the pathogenesis of inflammatory bowel disease (IBD) and multiple organ failure. The effect of Alaska pollock skin-derived collagen and its 3 tryptic hydrolytic fractions, HCP (6 kDa retentate), MCP (3 kDa retentate) and LCP (3 kDa permeate) …

Coined “The Mother of All Antioxidants” by Mark Hyman, MD, glutathione is one of the hottest topics in both natural health and medical circles today. Pronounced “gloota-thigh-own,” nearly 117,000 peer-reviewed scientific articles have addressed this powerhouse molecule, and experts are now recognizing that an alarming rate of people are deficient because of: Pre-mature aging Infections Chronic stress Injuries Environmental toxins So-called “health foods” Genetically modified foods Artificial sweeteners Overuse of antibiotics And radiation therapy that is all too easily given to cancer patients today. What Is Glutathione? Reduced glutathione, commonly known as glutathione or GSH, is a tripeptide consisting of L-glutamine, L-cysteine, and glycine. It is ubiquitous in living systems. Glutathione bio-synthesis can be affected by biochemical individuality and/or dietary factors. Chronic oxidative stress can also deplete cellular glutathione. Glutathione is naturally synthesized from N-Acetyl Cysteine (NAC) in the human body. Precursors to glutathione, such as whey protein, vitamin C, and glutamine, are also recommended to boost glutathione levels in the body; however, results are inconsistent. Biological individuality is such that not every body has equivalent ability to metabolize the precursor to raise glutathione.* Why Not Give Pure Glutathione? Unfortunately, most oral forms of glutathione are foul smelling, but more importantly, the majority of an oral dose is oxidized before it can be absorbed and used by the cells. Two different formula's offer a unique preparation of glutathione that overcomes these usual limitations. The stability of S-acetylglutathione and Liposomal Glutathione through the intestinal wall and the plasma is well documented. Oral intake of S-acetyl glutathione increases total glutathione and percent-reduced glutathione. Percent-reduced glutathione is a very significant biomarker of health status.* [1-5] The Two Most Absorbable Forms of Oral Glutathione* HormoneSynergy® S-acetyl glutathione or S-Acetyl Glutathione ULTRA, a lipid-like compound, is taken up intact by chylomicrons in the gut. The acetyl bond is placed on its thiol group or sulfur group, which prevents oxidation and allows the molecule to pass diffusively into the cell after absorption in the gut. The bond is then cleaved by non-specific enzymes inside the cell. Acetylation prevents the breakdown of glutathione, and S-acetyl glutathione does not require energy expenditure to be cleaved to reduced glutathione once it crosses the cell wall.* [1-8 S-Acetyl Glutathione S-Acetyl Glutathione ULTRA w/ NAC HormoneSynergy® Liposomal Glutathione Synergy  provides 500 mg of pure glutathione and activated B vitamin cofactors delivered in phosphatidylcholine liposomes for optimal absorption and bioavailability support.* Liposomal Glutathione Antioxidant Activity Glutathione functions extensively in tissues and organs throughout the body. It plays critical roles in protecting the body from oxidative stress, maintaining cellular functions, and supporting healthy immune function. [1,4] Many factors can increase cellular exposure to oxidative insult, and therefore increase cellular consumption of nutrients—such as glutathione—that provide antioxidant activity. This may result in a fierce cycle of oxidative stress and challenges to detoxification. Complete bio-transformation and protection from oxidative stress are important to maintaining cellular integrity and tissue health.* [2,5]

Fucoidan is a sulfated polysaccharide widely distributed in brown seaweed. It exhibits several bioactivities, such as anti-cancer, anti-tumor, anti-microbial, anti-diabetic and anti-oxidant properties. However, the effects of fucoidan in chondrocytes are not well established. Previously, we have reported in vitro and in vivo anti-inflammatory effects of fucoidan. In this study, we evaluated the effects and regulatory mechanism of fucoidan derived from Undaria pinnatifida on the cyclooxygenase-2 (COX-2) and type II collagen in rabbit articular chondrocytes. Using western blotting and alcian blue staining, respectively, fucoidan was shown to induce type II collagen and sulfated proteoglycan in a dose- and time-dependent manner. Moreover, fucoidan inhibited the COX-2 expression in a dose- and time-dependent manner and increased the phosphorylation of extracellular signal-regulated kinase (ERK), p38, and AKT kinases in chondrocytes. The inhibition of p38 and AKT using SB203580 and LY294002, respectively, in the presence of fucoidan decreased the expression of type II collagen. However, ERK inhibition using PD98050 stimulated type II collagen expression. Fucoidan increased COX-2 expression in the presence of inhibitors of ERK, p38, and AKT kinases. These results conclusively suggested that fucoidan regulated type II collagen expression via the p38 and AKT pathways, and COX-2 expression via the p38, ERK and AKT pathways in rabbit articular chondrocytes. Moreover, given its ability to mediate cell differentiation and exert anti-inflammatory activity, fucoidan may represent a potential therapeutic substance for use in inflammatory conditions, including arthritis.