Growth Inhibition by Novel Liposomes Including Trehalose Surfactant Ag (...)
Novel liposomes composed of L-α-dimyristoylphosphatidylcholine (DMPC) and trehalose surfactant (DMTreCn) were produced by the method of sonication in buffer solution. The thickness of fixed aqueous layer of DMTreCn was larger than that of DMPC liposomes and increased in a dose-dependent manner. The remarkable inhibitory effects of DMTreCn on the growth of human hepatocellular carcinoma (HCC) (Hep-G2 and HuH-7) cells were obtained along with apoptosis, without affecting the growth of normal cells. DMTreCn induced apoptosis of Hep-G2 and HuH-7 cells through the activation of caspase-3, 8 and 9. Release of cytochrome c from mitochondria and activation of Bcl-2 family protein (BAX) were recorded, indicating that DMTreCn induced apoptosis of Hep-G2 and HuH-7 cells through mitochondrial pathway via BAX. It is noteworthy that the remarkable inhibitory effects of DMTreCn on the growth of human HCC cells were obtained along with apoptosis for the first time.
Viral Fighting Amino Acids (Natural Support for Coronavirus) - YouTube
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L-Glutamine Supplement - https://bit.ly/2q6bZmi
Virid - https://bit.ly/2U1gY4Q
For viral outbreaks, including coronavirus, many people are taking supplements to support their immune systems. Vitamin C, zinc, vitamin D, vitamin A, and elderberry are all effective support strategies, but one of the most ignored yet potent strategies come in the form of viral fighting amino acids.
The top amino acids to support immune function include NAC, AKA N-Acetyl-Cysteine, and L-glutamine.
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*These statements have not been evaluated by the Food and Drug Administration. This video is not intended to diagnose, treat, cure or prevent any disease. It is strictly intended for educational purposes only. Additionally, this information is not intended to replace the advice of your physician. Dr. Osborne is not a medical doctor. He does not treat or diagnose disease. He offers nutritional support to people seeking an alternative from traditional medicine. Dr. Osborne is licensed with the Pastoral Medical Association.
What Every Doctor Should Know About Glutathione - Holistic Primary Care
Glutathione, a powerful endogenous antioxidant, has been the subject of growing scientific interest. Deficiency is increasingly recognized as a risk factor in heart disease, asthma, neurodegenerative disorders and various types of cancer. Supplementation can greatly improve management of many of these conditions.
The use of natural and synthetic phospholipids as pharmaceutical excipients - van Hoogevest - 2014 - European Journal of Lipid Science and Technology - Wiley Online Library
For selection of phospholipid excipients for pharmaceutical formulations, natural phospholipids are preferred compared to synthetic phospholipids because they are available at large scale with reprod...
Therapeutic effects of trehalose liposomes against lymphoblastic leuke (...)
Inhibitory effects of trehalose liposomes (DMTre) composed of 30mol% l-α-dimyristoylphosphatidylcholine (DMPC) and 70mol% trehalose surfactants on the growth of lymphoblastic leukemia (MOLT-4) cells in vitro and therapeutic effects of DMTre for xenograft mice model of carcinoma in vivo were examined …
Doctor's Best Lumbrokinase 20 mg 60 Veg Caps - Swanson Health Products
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Glutathione, a powerful endogenous antioxidant, has been the subject of growing scientific interest. Deficiency is increasingly recognized as a risk factor in heart disease, asthma, neurodegenerative disorders and various types of cancer. Supplementation can greatly improve management of many of these conditions.
Therapeutic effects of trehalose liposomes against lymphoblastic leukemia leading to apoptosis in vitro and in vivo. - PubMed - NCBI
Inhibitory effects of trehalose liposomes (DMTre) composed of 30mol% l-α-dimyristoylphosphatidylcholine (DMPC) and 70mol% trehalose surfactants on the growth of lymphoblastic leukemia (MOLT-4) cells in vitro and therapeutic effects of DMTre for xenograft mice model of carcinoma in vivo were examined …
Trehalose Liposomes Suppress the Growth of Tumors on Human Lung Carcin (...)
Background/Aim: Previous evidence demonstrates that trehalose liposomes (DMTreC14) composed of L-α-dimyristoylphosphatidylcholine (DMPC) and α-D-glycopyranosyl-α-D-glucopyranoside monomyristate (TreC14) inhibit proliferation and invasion on lung carcinoma (A549 cells) in vitro. Here, we aimed to investigate suppressive effects of DMTreC14 on the growth of tumor on human lung carcinoma bearing mice. Materials and Methods: DMTreC14 composed of 30 mol% DMPC and 70 mol% TreC14 were prepared by the sonication method. Anti-tumor activities of DMTreC14 using the subcutaneous and orthotopic graft-bearing mice of A549 cells were investigated in vivo. Results: The remarkable reduction of volume and weight in subcutaneous tumors on subcutaneous lung carcinoma-bearing mice topically administrated with DMTreC14 were obtained. Apoptotic-positive cells in the subcutaneous tumor slice of subcutaneous lung carcinoma-bearing mice topically administrated with DMTreC14 were observed using TUNEL staining. Lung weights on the orthotopic graft-bearing mice of lung carcinoma intravenously administrated with DMTreC14 were markedly decreased compared to those of the control group. Remarkable decrease in dimensions of tumor area of lung on the orthotopic graft-bearing mice of lung carcinoma intravenously administrated with DMTreC14 was obtained in histological analysis using the hematoxylin and eosin staining. Conclusion: Remarkably high anti-tumor activities of DMTreC14 for the subcutaneous and orthotopic graft-bearing mice of lung carcinoma accompanied with apoptosis were revealed for the first time in vivo.
Essential Glutathione The Mother of All Antioxidants Dr. Mark Hyman
IT’S THE MOST IMPORTANT MOLECULE you need to stay healthy and prevent disease — yet you’ve probably never heard of it. It’s the secret to prevent aging, cancer, heart disease, […]
LIVESTRONG.COM provides the blueprint to simple healthy living. Our mission is to empower anyone at any age or stage in their fitness journey with the information and tools that will help them to make better choices – even just one small better choice can motivate them and improve their potential to truly thrive.
A comparative study of colostrum dressing versus conventional dressing in deep wounds. - PubMed - NCBI
Colostrum powder dressings are safe, promoter of wound healing, more patient compliance in terms of less pain, less number of dressing required. This treatment though found to be more expensive than conventional dressings; results indicate that colostrum powder dressings may be used as an adjunct in …
Side Effects of Glutathione Supplements Livestrong.com
Glutathione supplements may offer some health benefits from their antioxidant content. But be aware glutathione side effects can result from improper use.
A Comparative Study of Colostrum Dressing Versus Conventional Dressing in Deep Wounds
Deep wounds are extending deeper, across deep fascia into muscles or deeper structures. Understanding of nutrition, immunology, psychological issues, the physiology and the metabolic interactions require for optimal treatment of deep wounds. Wound dressing ...
A mere drop of blood makes skin cells line up Researchers discover wound healing initiation without a wound -- ScienceDaily
A team of researchers performed experiments on blood-deprived cells that were subsequently exposed to blood serum. Remarkably, all the cells started to move and grow in the same direction as soon as the blood serum was added.
Chitosan-glucan Complex Hollow Fibers Reinforced Collagen Wound Dressing Embedded with Aloe vera. Part I Preparation and Characterization - ScienceDirect
Collagen (CO)/chitosan-glucan complex (CSGC) hollow fibers encapsulated aloe vera (AV) dressing scaffold (CO/CSGC@AV) were fabricated for the first ti…
Collagen dressing versus conventional dressings in burn and chronic wounds a retrospective study. - PubMed - NCBI
No significant better results in terms of completeness of healing of burn and chronic wounds between collagen dressing and conventional dressing were found. Collagen dressing, however, may avoid the need of skin grafting, and provides additional advantage of patients' compliance and comfort.
Coined “The Mother of All Antioxidants” by Mark Hyman, MD, glutathione is one of the hottest topics in both natural health and medical circles today. Pronounced “gloota-thigh-own,” nearly 117,000 peer-reviewed scientific articles have addressed this powerhouse molecule, and experts are now recognizing that an alarming rate of people are deficient because of: Pre-mature aging Infections Chronic stress Injuries Environmental toxins So-called “health foods” Genetically modified foods Artificial sweeteners Overuse of antibiotics And radiation therapy that is all too easily given to cancer patients today. What Is Glutathione? Reduced glutathione, commonly known as glutathione or GSH, is a tripeptide consisting of L-glutamine, L-cysteine, and glycine. It is ubiquitous in living systems. Glutathione bio-synthesis can be affected by biochemical individuality and/or dietary factors. Chronic oxidative stress can also deplete cellular glutathione. Glutathione is naturally synthesized from N-Acetyl Cysteine (NAC) in the human body. Precursors to glutathione, such as whey protein, vitamin C, and glutamine, are also recommended to boost glutathione levels in the body; however, results are inconsistent. Biological individuality is such that not every body has equivalent ability to metabolize the precursor to raise glutathione.* Why Not Give Pure Glutathione? Unfortunately, most oral forms of glutathione are foul smelling, but more importantly, the majority of an oral dose is oxidized before it can be absorbed and used by the cells. Two different formula's offer a unique preparation of glutathione that overcomes these usual limitations. The stability of S-acetylglutathione and Liposomal Glutathione through the intestinal wall and the plasma is well documented. Oral intake of S-acetyl glutathione increases total glutathione and percent-reduced glutathione. Percent-reduced glutathione is a very significant biomarker of health status.* [1-5] The Two Most Absorbable Forms of Oral Glutathione* HormoneSynergy® S-acetyl glutathione or S-Acetyl Glutathione ULTRA, a lipid-like compound, is taken up intact by chylomicrons in the gut. The acetyl bond is placed on its thiol group or sulfur group, which prevents oxidation and allows the molecule to pass diffusively into the cell after absorption in the gut. The bond is then cleaved by non-specific enzymes inside the cell. Acetylation prevents the breakdown of glutathione, and S-acetyl glutathione does not require energy expenditure to be cleaved to reduced glutathione once it crosses the cell wall.* [1-8 S-Acetyl Glutathione S-Acetyl Glutathione ULTRA w/ NAC HormoneSynergy® Liposomal Glutathione Synergy provides 500 mg of pure glutathione and activated B vitamin cofactors delivered in phosphatidylcholine liposomes for optimal absorption and bioavailability support.* Liposomal Glutathione Antioxidant Activity Glutathione functions extensively in tissues and organs throughout the body. It plays critical roles in protecting the body from oxidative stress, maintaining cellular functions, and supporting healthy immune function. [1,4] Many factors can increase cellular exposure to oxidative insult, and therefore increase cellular consumption of nutrients—such as glutathione—that provide antioxidant activity. This may result in a fierce cycle of oxidative stress and challenges to detoxification. Complete bio-transformation and protection from oxidative stress are important to maintaining cellular integrity and tissue health.* [2,5]
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Our collagen, made of ONE simple ingredient is a dietary supplement with a beneficial combination of amino acids. At Great Lakes Gelatin Company, we believe that a healthy lifestyle and a balanced diet including collagen, is the cornerstone to a life well-lived. Collagen is nearly tasteless, colorless, and odorless, and it is easily digested. It will not congeal in cold liquids making it a perfect addition to cold and hot beverages, smoothies or recipes. Just mix in and enjoy!
Ingredients: Bovine Collagen Hydrolysate
Collagen Types 1 & 3
Grass-Fed & Pasture-Raised, Kosher, Paleo-Friendly, Keto-Certified
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Using a tablespoon or scoop, add 2 tablespoons of Collagen Hydrolysate and pour slowly into your beverage of choice.
Stir until dissolved. Hot liquids will dissolve the collagen more quickly, while colder liquids will take a bit longer.
Once the collagen is dissolved, enjoy your collagen-packed drink!
Many customers enjoy adding collagen to:
Coffee
Tea
Smoothies
Oatmeal
Yogurt
Orange juice
Water (with or without a lemon slice)
Soup
For more ideas visit our Recipes Page!
Collagen peptide supplementation in combination with resistance training improves body composition and increases muscle strength in elderly sarcope... - PubMed - NCBI
Protein supplementation in combination with resistance training may increase muscle mass and muscle strength in elderly subjects. The objective of this study was to assess the influence of post-exercise protein supplementation with collagen peptides v. placebo on muscle mass and muscle function foll …
Collagen peptides ameliorate intestinal epithelial barrier dysfunction in immunostimulatory Caco-2 cell monolayers via enhancing tight junctions. - PubMed - NCBI
Dysfunction of the intestinal barrier plays a key role in the pathogenesis of inflammatory bowel disease (IBD) and multiple organ failure. The effect of Alaska pollock skin-derived collagen and its 3 tryptic hydrolytic fractions, HCP (6 kDa retentate), MCP (3 kDa retentate) and LCP (3 kDa permeate) …
Nebulized Glutathione Induces Bronchoconstriction in Patients with Mild Asthma American Journal of Respiratory and Critical Care Medicine
To assess the effects on bronchial responsiveness of nebulized glutathione (GSH), one of the most efficient scavengers of oxidant substances in the airways, we studied eight patients with mild asth...