L-Arginine-Nitric Oxide-Asymmetric Dimethylarginine Pathway and the Coronary Circulation Translation of Basic Science Results to Clinical Practice
By 1980, it was thought that we already knew most of the major mechanisms regulating vascular tone. However, after the somewhat serendipity discovery that endothelium is involved in mediation of relaxation to acetylcholine, a whole new world opened up ...
The Effects of Oral l-Arginine and l-Citrulline Supplementation on Blood Pressure
Nitric oxide (NO) is a well-known vasodilator produced by the vascular endothelium via the enzyme endothelial nitric oxide synthase (eNOS). The inadequate production of NO has been linked to elevated blood pressure (BP) in both human and animal studies, ...
Uric Acid - A Pivotal Player in Metabolic Diseases - Dr. David Perlmutter
Having elevated uric acid indicates high blood pressure. New research demonstrates that lowering uric acid with allopurinol results in lower blood pressure.
Analytical techniques for serratiopeptidase A review
A review is presented on different analytical techniques used for qualitative and quantitative analysis of serratiopeptidase, a proteolytic enzyme, which has recently gained importance as an anti-inflammatory agent. Efforts have been made to collate all ...
In vitro and in vivo insulin amyloid degradation mediated by Serratiopeptidase - ScienceDirect
A transition of amyloidogenic protein by alternative folding pathway under certain conditions leads to the formation of protease resistant amyloid fib…
The role of serratiopeptidase in the resolution of inflammation - ScienceDirect
Inflammation remains a key event during most of the diseases and physiological imbalance. Acute inflammation is an essential physiological event by im…
Boluoke® (lumbrokinase) is the only fully researched oral fibrinolytic supplement on the market. Besides having in vitro studies, animal studies, toxicity studies, and pharmacokinetic studies done, Boluoke® has also been put through all phases of clinical trials (including randomized double blind controlled studies) in China. Lumbrokinase has been studied as a treatment for various clinical conditions, including acute, sub-acaute, and chronic conditions that are associated with the presence of hypercoagulation and hypoperfusion. Boluoke® seems to be beneficial for any illness that has an accompanying hypercoagulable blood state, which has been shown to be present in many chronic illnesses. Some practitioners are also recommending Boluoke® for those who choose to be on hormone replacement therapy or birth control pills, and for those who could not tolerate standard preventative pharmaceutical drugs. Recommended Use As a dietary supplement, if Boluoke® is to be
Consequence of patient substitution of nattokinase for warfarin after aortic valve replacement with a mechanical prosthesis
This report describes a patient's self-substitution of nattokinase for the vitamin K antagonist warfarin after aortic valve replacement with a mechanical prosthesis. Nattokinase is an enzyme derived from a popular fermented soybean preparation in Japan ...
Doctor's Best Lumbrokinase 20 mg 60 Veg Caps - Swanson Health Products
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Frontiers Sirt1 Activation by Post-ischemic Treatment With Lumbrokinase Protects Against Myocardial Ischemia-Reperfusion Injury Pharmacology
Lumbrokinase is used as an oral supplement to support and maintain healthy cardiovascular function, and to treat cardiovascular diseases in clinical for more than 10 years. Up until now, the mechanism of the cardioprotective effects of post-ischemic treatment with lumbrokinase has remained unclear. We therefore investigated the signaling pathways involved in the amelioration of myocardial ischemia-reperfusion (I-R) injury in rats treated with lumbrokinase 20 min after myocardial ischemia. Compared to vehicle-treated rats, post-ischemic treatment with lumbrokinase was associated with significant reductions in myocardial I-R-induced arrhythmias and myocardial damage, and an improvement in cardiac function. Moreover, lumbrokinase significantly upregulated levels of silent information regulator 1 (Sirt1). In addition, lumbrokinase significantly increased manganese-dependent superoxide dismutase expression, decreased Cleaved-Caspase-3 expression, and induced deacetylation of FoxO1. On the other hand, lumbrokinase also significantly downregulated levels of succinate dehydrogenase, cytochrome c oxidase, nuclear factor kappa B (NF-κB) and elevated levels of microtubule-associated protein light chain 3. Notably, the cardioprotective effects of lumbrokinase were abolished by administration of the specific Sirt1 inhibitor EX527. These findings demonstrate that post-ischemic treatment with lumbrokinase attenuates myocardial I-R injury through the activation of Sirt1 signaling, and thu...
Lumbrokinase For More Than Just Circulatory Health (May 2018) Townsend Letter, Alternative Medicine Magazine
Lumbrokinase An Enzyme for More Than Just Circulatory Health! by Martin Kwok, BSc, MSAOM, ND** Townsend Letter, the Examiner of Alternative Medicine alternative medicine magazine articles are written by researchers, health practitioners and patients.
Nattokinase A Promising Alternative in Prevention and Treatment of Cardiovascular Diseases
Cardiovascular disease (CVD) is the leading cause of death in the world and our approach to the control and management of CVD mortality is limited. Nattokinase (NK), the most active ingredient of natto, possesses a variety of favourable cardiovascular ...
Shop Trebinase 320,000 FU's Per Capsule - Pivotal Health Products
Trebinase contains 320,000 FU's per serving while only requiring 3 capsules per day. Trebinase contains Serrapeptase, Nattokinase and Seaprose. Trebinase is the strongest systemic Enzyme of the Market
Stop Blood Clots With Lumbrokinase (Boluoke) Institute for Progressive Medicine
[et_pb_section bb_built=”1″][et_pb_row][et_pb_column type=”4_4″][et_pb_text] Blood clots cause heart attacks, strokes, phlebitis, blockage of lung arteries, often leading to severe illness or sudden death. Persons who spend hours in sitting positions, such as in plane flights or long distance driving, are especially susceptible to blood clots forming in their legs, then breaking off and going to the […]
