Advances in treatment of ulcerative colitis with herbs From bench to bedside
Ulcerative colitis (UC), an idiopathic inflammatory disorder in the colon, has become a clinical challenge, owing to the increasing incidence and poor prognosis. The conventional treatments for UC including aminosalicylates, corticosteroids, and immunosuppressants, ...
A non-traditional use for probiotics illness in athletes Examine.com
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A single species of gut bacteria can reverse autism-related social beh (...)
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Acemannan and Fructans from Aloe vera (Aloe barbadensis Miller) plants (...)
The nutraceutical properties of Aloe vera have been attributed to a glucomannan known as acemannan. Recently information has been published about the presence of fructans in Aloe vera but there are no publications about acemannan and fructans as prebiotic compounds. This study investigated in vitro the prebiotic properties of these polysaccharides. Our results demonstrated that fructans from Aloe vera induced bacterial growth better than inulin (commercial FOS). Acemannan stimulated bacterial growth less than fructans, and as much as commercial FOS. Using qPCR to study the bacterial population of human feces fermented in a bioreactor simulating colon conditions, we found that fructans induce an increase in the population of Bifidobacterium spp. Fructans produced greater amounts of short chain fatty acids (SCFA), while the branched-chain fatty acids (BCFA) did not increase with these polysaccharides. Acemannan increased significantly acetate concentrations. Therefore, both Aloe vera polysaccharides have prebiotic potentials.
Aerobic Exercise and the Health of Your Microbiome
Now the more interesting question: if one begins a new exercise regimen, would s/he see a change, or improvement, in the diversity of bacteria in the gut.
Alterations in the mucosa-associated bacterial composition in Crohn’s (...)
Introduction Changes in the intestinal bacterial composition seem to play a major role in the pathogenesis and in the clinical course of inflammatory bowel diseases (IBD), which consist of Crohn’s disease (CD), and ulcerative colitis (UC). Mutations in the NOD2 gene are the most important genetic risk factors for the development of CD. In this study, the association between mucosal biopsies and the mucosa-associated bacterial composition from CD and UC patients regarding their genetic risk factors (mutations in the NOD2 gene), their endoscopic activity, and their medical therapy (TNF-α blocking therapy) was examined. Material and methods Seventy biopsies from routine colonoscopies from 33 IBD patients (26 CD and 7 UC) were obtained. Disease activity and clinical characteristics were assessed. Seven different bacterial strains (Bacteroides fragilis, Escherichia coli, Prevotella melaninogenica, Clostridium coccoides, Clostridium difficile, Bifidobacterium bifidum, and Faecalibacterium prausnitzii) were quantified using real-time PCR. NOD2 genotyping from patients with CD was performed. Results Five of the 24 patients were positive for at least one mutation in the NOD2 gene. The bacterial composition was different in CD compared to UC, in macroscopic healthy compared to macroscopic inflamed biopsies, in NOD2 mutated compared to NOD2 wildtype patients, and in patients receiving TNF-α blocking therapy compared to patients without this treatment. Conclusion This study further characterizes the mucosa-associated bacteria in IBD patients. Different clinical situations lead to an altered mucosa-associated bacterial composition. The analyzed bacteria could be promising targets for cost-effective surveillance or therapies in IBD patients.
Another reason to break the habit Smoking alters bacterial balance in (...)
Smoking drastically alters the oral microbiome, the mix of roughly 600 bacterial species that live in people's mouths, a new study has found. The researchers say their analysis is the most comprehensive to date to examine the effects of smoking on the make-up and action of bacterial species in the human mouth based on precise genetic testing.
Antibiotic gel squirted into the ear could provide a one dose cure for (...)
A single-application bioengineered gel, squirted in the ear canal, could deliver a full course of antibiotic therapy for middle ear infections, making treatment of this common childhood illness much easier and potentially safer, a preclinical study finds.
Antibiotic treatment for Tuberculosis induces a profound dysbiosis of (...)
Mycobacterium tuberculosis, the cause of Tuberculosis (TB), infects one third of the world's population and causes substantial mortality worldwide. In its shortest format, treatment of TB requires six months of multidrug therapy with a mixture of broad spectrum and mycobacterial specific antibiotics …
Antibiotics - A gift and a curse on the gut - YouTube
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*These statements have not been evaluated by the Food and Drug Administration. This video is not intended to diagnose, treat, cure or prevent any disease. It is strictly intended for educational purposes only. Additionally, this information is not intended to replace the advice of your physician. Dr. Osborne is not a medical doctor. He does not treat or diagnose disease. He offers nutritional support to people seeking an alternative from traditional medicine. Dr. Osborne is licensed with the Pastoral Medical Association.
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Antibiotics can be a controversial topic. While they can help tremendously for some specific infections in the body, they can also wreak havoc in the gut and beyond when overused or misused...But how far can their damage go? Can they really increase the risk of developing gluten sensitivity and celiac disease? The short answer is yes, but it’s not that simple. To understand the relationship between the two, we first need to take a look at how antibiotics impact the gut and how this can lead to complications and allergies down the road.
00:00 - Introduction to Antibiotics and Your Gut
01:00 - CDC Antibiotic Statistics
06:00 - Is it Viral, Bacterial, or Fungal?
12:00 - Impact of Antibiotics on the Gut
17:00 - Dysbiosis: Bacterial Imbalances
27:00 - Role of the Gut Microbiota
35:00 - Finding the right Probiotic
37:00 - Live Q&A
To connect with Dr. Osborne visit:
On the web: https://drpeterosborne.com/
Facebook: https://www.facebook.com/DoctorPeterO...
Pinterest: https://www.pinterest.com/docosborne/
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Twitter: https://twitter.com/glutenology
*These statements have not been evaluated by the Food and Drug Administration. This video is not intended to diagnose, treat, cure or prevent any disease. It is strictly intended for educational purposes only. Additionally, this information is not intended to replace the advice of your physician. Dr. Osborne is not a medical doctor. He does not treat or diagnose disease. He offers nutritional support to people seeking an alternative from traditional medicine. Dr. Osborne is licensed with the Pastoral Medical Association.
Antibiotics pave way for C. diff infections by killing bile acid-alter (...)
Bile acids, which are altered by bacteria normally living in the large intestine, inhibit the growth of Clostridium difficile, new research indicates. The work sheds light on the ways in which some commonly used antibiotics can promote C. diff infections by killing off the bile acid-altering microbes.
Antibiotics that kill gut bacteria also stop growth of new brain cells (...)
Antibiotics strong enough to kill off gut bacteria can also stop the growth of new brain cells in the hippocampus, a section of the brain associated with memory, reports a new study in mice. Researchers also uncovered a clue to why -- a type of white blood cell seems to act as a communicator between the brain, the immune system, and the gut.
Anticancer effects of the microbiome and its products. - PubMed - NCBI
The human gut microbiome modulates many host processes, including metabolism, inflammation, and immune and cellular responses. It is becoming increasingly apparent that the microbiome can also influence the development of cancer. In preclinical models, the host response to cancer treatment has been …
Are Your Apples Full of Antibiotic Drugs GreenMedInfo Blog Entry
Hard as you try, you may not be able to avoid antibiotics completely. In fact, you’re probably even getting a low dose of antibiotics in your apples and cabbage
Autism Symptoms Alleviated with Fecal Microbiota Transplantation Natu (...)
ReferenceKang DW, Adams JB, Gregory AC, et al. Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study. Microbiome. 2017 Jan 23;5(1):10.DesignProspective, open-label, uncontrolled pilot studyParticipantsEighteen children between the ages of 7 and 16 with an autism spectrum disorder (ASD) diagnosis and moderate to severe gastrointestinal (GI) problems.
